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NewsMOLECULAR IMMUNOLOGYSaturday, May 2, 2026 · May 2, 2026

Phillyrin attenuates TGF-β1-induced pulmonary fibrosis by modulating the Nrf2/HO-1 pathway and epithelial-mesenchymal transition.

WHY IT MATTERS

Recent peer-reviewed research on Idiopathic pulmonary fibrosis that may be relevant for patients and caregivers.

Phillyrin (Phi), a natural lignan glycoside derived from Fructus Forsythiae, has been reported to exhibit anti-inflammatory and antioxidant activities. In this study, we investigated its therapeutic potential in a TGF-β1-induced model of epithelial-mesenchymal transition (EMT) in A549 human al...

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Read the original at Molecular immunology
ResearchPubMedIdiopathic pulmonary fibrosisEpithelial-Mesenchymal TransitionHumans

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