Linear Interstitial Keratitis - A Retrospective Chart Review of a Rare Entity.
WHY IT MATTERS
This is the largest study to date on linear interstitial keratitis, providing eye doctors with new guidance on diagnosis and treatment options for a condition that previously had no agreed-upon management approach.
Linear interstitial keratitis (LIK) is a very rare eye condition where a thin line of cloudiness forms in the clear part of the eye (the cornea). This study looked at 6 patients with this condition to better understand what it looks like, how doctors can diagnose it, and what treatments work best. The researchers found that the cloudy line usually appears near the edge of the cornea and can be seen clearly with special eye imaging tools.
Linear Interstitial Keratitis - A Retrospective Chart Review of a Rare Entity. Abstract: BACKGROUND: Linear interstitial keratitis (LIK) is a rare variant of interstitial keratitis and is characterised by a sharply demarcated stromal band of opacity with uncertain pathophysiology and no consensus management. We report the largest contemporary study to characterise phenotype, diagnostics, treatment, and outcomes. METHODS: This is a retrospective, investigator-initiated study across two university hospitals. Extracted data included demographics, clinical features, microbiology/serology, anterior segment imaging, treatments and outcomes. RESULTS: Six unilateral cases were included (five males, one female). LIK presented as a sharply demarcated linear stromal opacity of variable, often near limbus-to-limbus, extent. AS-OCT commonly localised the lesion to the anterior stroma, whil Authors: Blaser et al. Journal: Klinische Monatsblatter fur Augenheilkunde MeSH: Humans, Male, Female, Retrospective Studies, Keratitis, Middle Aged, Adult, Aged, Rare Diseases, Treatment Outcome
ASK YOUR DOCTOR
If you have been diagnosed with linear interstitial keratitis or have unexplained corneal cloudiness, ask your eye doctor if they are aware of this research and whether the diagnostic and treatment approaches described might apply to your case.