What is Torsade-de-pointes syndrome with short coupling interval?
Torsade-de-pointes syndrome with short coupling interval does not yet have FDA-approved treatments tracked on UniteRare.
Key symptoms:
Sudden fainting or loss of consciousnessRapid, pounding, or fluttering heartbeat (palpitations)Dizziness or lightheadednessSeizure-like shaking episodesSudden cardiac arrest (heart stops pumping effectively)Chest discomfort before an episodeShortness of breath during an episodeWaking suddenly from sleep with a racing heart
- Inheritance
- Variable
- Can be inherited in different ways depending on the underlying gene
- Age of Onset
- Variable
- Can begin at different ages, from infancy through adulthood
Treatments
Source: openFDA + DailyMed · NDA / BLA labels with structured indications · refreshed weekly
No FDA-approved treatments are currently listed for Torsade-de-pointes syndrome with short coupling interval.
View clinical trials →Clinical Trials
View all trials with filters →Source: ClinicalTrials.gov · synced daily · phases, status, and PI names normalized at ingest
No actively recruiting trials found for Torsade-de-pointes syndrome with short coupling interval at this time.
New trials open frequently. Follow this disease to get notified.
Specialists
View all specialists →Source: NPI Registry + PubMed · trial PI roles cross-referenced with ClinicalTrials.gov · ranked by match score (publications + PI activity + community signal)
No specialists are currently listed for Torsade-de-pointes syndrome with short coupling interval.
Treatment Centers
8 centersSource: NORD Rare Disease Centers + NIH Undiagnosed Diseases Network (UDN) · centers verified active within last 12 months
Children's Hospital Colorado Rare Disease Program ↗
Children's Hospital Colorado
📍 Aurora, CO
👤 Boston Children's Hospital Rare Disease Program
🔬 UDNHarvard/MGH UDN Clinical Site ↗
Massachusetts General Hospital
📍 Boston, MA
🏥 NORDBoston Children's Hospital Rare Disease Program ↗
Boston Children's Hospital
📍 Boston, MA
👤 Boston Children's Hospital Rare Disease Program
🏥 NORDUCLA Rare Disease Day Program ↗
UCLA Health
📍 Los Angeles, CA
🏨 Children'sAnn & Robert H. Lurie Children's Hospital Genetics ↗
Lurie Children's Hospital
📍 Chicago, IL
👤 Boston Children's Hospital Rare Disease Program
🏥 NORDCincinnati Children's Hospital Medical Center ↗
Cincinnati Children's
📍 Cincinnati, OH
👤 Boston Children's Hospital Rare Disease Program
🏨 Children'sNationwide Children's Hospital Rare Disease Center ↗
Nationwide Children's Hospital
📍 Columbus, OH
👤 Boston Children's Hospital Rare Disease Program
🔬 UDNNIH Clinical Center Undiagnosed Diseases Program ↗
National Institutes of Health
📍 Bethesda, MD
Travel Grants
No travel grants are currently matched to Torsade-de-pointes syndrome with short coupling interval.
Community
No community posts yet. Be the first to share your experience with Torsade-de-pointes syndrome with short coupling interval.
Start the conversation →Latest news about Torsade-de-pointes syndrome with short coupling interval
Source: PubMed + NIH RePORTER + openFDA + clinical-journal RSS · last 30 days · disease-tagged at ingest by AI extraction with human QC
No recent news articles for Torsade-de-pointes syndrome with short coupling interval.
Follow this condition to be notified when news becomes available.
Caregiver Resources
NORD Caregiver Resources
Support, advocacy, and financial assistance for caregivers of rare disease patients.
Mental Health Support
Rare disease caregiving can be isolating. Connect with counseling and peer support.
Family & Caregiver Grants
Financial assistance programs specifically for caregivers of rare disease patients.
Social Security Disability
Learn how rare disease patients may qualify for SSDI/SSI benefits.
Questions for your doctor
Bring these to your next appointment
- Q1.Do I need an implantable defibrillator (ICD), and what are the risks and benefits for me specifically?,Should I be taking verapamil or another medication, and are there any drugs I must avoid?,Should my family members be tested or screened for this condition?,Are there any activities, sports, or situations I should avoid?,What should I or my family do if I collapse or have a cardiac arrest?,Should I have genetic testing, and what would a positive or negative result mean for me and my family?,How often do I need follow-up appointments and heart monitoring?
Common questions about Torsade-de-pointes syndrome with short coupling interval
What is Torsade-de-pointes syndrome with short coupling interval?
Torsade-de-pointes syndrome with short coupling interval (also called short-coupled torsade de pointes, or SC-TdP) is a rare and serious heart rhythm disorder. In this condition, the heart can suddenly go into a dangerous, fast, and chaotic rhythm called torsade de pointes (TdP), which means 'twisting of the points' in French — named after the way the heartbeat pattern looks on an ECG (heart tracing). What makes this form unique is that the dangerous rhythm is triggered very quickly after a normal heartbeat, with an unusually short gap between the two — this is called a 'short coupling interva
Frequently asked questions about Torsade-de-pointes syndrome with short coupling interval
Auto-generated from canonical disease facts (Orphanet, OMIM, ClinicalTrials.gov, openFDA, NPPES). Not a substitute for clinical guidance.
What is Torsade-de-pointes syndrome with short coupling interval?
Torsade-de-pointes syndrome with short coupling interval is a rare disease catalogued in international rare-disease ontologies (Orphanet ORPHA:51084, OMIM 613600). It is typically inherited as variable. Age of onset is generally variable. For verified primary sources, see the UniteRare Torsade-de-pointes syndrome with short coupling interval page.
How is Torsade-de-pointes syndrome with short coupling interval inherited?
Torsade-de-pointes syndrome with short coupling interval follows variable inheritance. Genetic counseling is recommended for affected families to understand recurrence risk in offspring and the likelihood of unaffected siblings being carriers. Variants in the underlying gene(s) may be identified via clinical genetic testing.
Are there FDA-approved treatments for Torsade-de-pointes syndrome with short coupling interval?
Approved treatments for Torsade-de-pointes syndrome with short coupling interval are tracked from openFDA and DailyMed primary sources. Many rare diseases have no specific FDA-approved therapy; for those, supportive care and management of complications form the basis of clinical care. Orphan-drug-designation status is noted where applicable.
Are there clinical trials for Torsade-de-pointes syndrome with short coupling interval?
Active clinical trials for Torsade-de-pointes syndrome with short coupling interval are tracked daily from ClinicalTrials.gov. Trial availability changes frequently; check the UniteRare trial listings for the current count and recruitment status. Sponsors of rare-disease research often welcome inquiries even when a trial is not actively recruiting at a given moment.
How do I find a specialist for Torsade-de-pointes syndrome with short coupling interval?
Verified Torsade-de-pointes syndrome with short coupling interval specialists are identified through ClinicalTrials.gov principal-investigator records, peer-reviewed publication authorship (via PubMed), and the NPPES NPI registry. NORD-designated Centers of Excellence and NIH-affiliated rare-disease clinics are also tracked. UniteRare's specialist directory is updated continuously as new evidence becomes available.
See full Torsade-de-pointes syndrome with short coupling interval page for complete clinical details, sources, and verified-specialist listings.
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