Overview
Supernumerary breasts, also known as polymastia or accessory breasts, is a congenital condition in which one or more additional breast tissues develop along the embryonic mammary ridge (milk line), which extends from the axilla (armpit) to the groin on both sides of the body. This condition results from incomplete regression of the mammary ridge during fetal development. The extra breast tissue may range from a small amount of glandular tissue without a visible nipple to a fully formed accessory breast with a nipple and areola. The most common location for supernumerary breasts is the axillary (underarm) region or just below the normal breast on the chest or abdomen. The condition affects the integumentary system and, in some cases, the underlying soft tissues of the chest or abdominal wall. Supernumerary breasts are usually present from birth but may become more noticeable during puberty, pregnancy, or lactation, when hormonal changes cause the accessory tissue to enlarge, become tender, or even produce milk. In most cases, the condition is benign and asymptomatic, though it can cause cosmetic concerns, discomfort, or psychological distress. Importantly, accessory breast tissue is subject to the same pathological conditions as normal breast tissue, including fibroadenomas, cysts, and, rarely, breast carcinoma. Therefore, clinical surveillance may be recommended, particularly if the tissue is glandular. Treatment is generally not required unless the individual experiences symptoms, cosmetic concerns, or complications. Surgical excision is the standard treatment when intervention is desired, and it is typically curative. Supernumerary breasts can occur as an isolated finding or, less commonly, in association with other congenital anomalies, including renal or urinary tract malformations, though this association remains debated in the literature.
Also known as:
Variable
Can be inherited in different ways depending on the underlying gene
Neonatal
Begins at or shortly after birth (first 4 weeks)
FDA & Trial Timeline
3 eventsKing's College London
Data sourced from FDA regulatory filings and ClinicalTrials.gov. Updated periodically.
Treatments
No FDA-approved treatments are currently listed for Supernumerary breasts.
View clinical trials →Clinical Trials
View all trials with filters →No actively recruiting trials found for Supernumerary breasts at this time.
New trials open frequently. Follow this disease to get notified.
Treatment Centers
8 centersBaylor College of Medicine Rare Disease Center ↗
Baylor College of Medicine
📍 Houston, TX
🏥 NORDStanford Medicine Rare Disease Center ↗
Stanford Medicine
📍 Stanford, CA
🔬 UDNNIH Clinical Center Undiagnosed Diseases Program ↗
National Institutes of Health
📍 Bethesda, MD
🔬 UDNUCLA UDN Clinical Site ↗
UCLA Health
📍 Los Angeles, CA
🔬 UDNBaylor College of Medicine UDN Clinical Site ↗
Baylor College of Medicine
📍 Houston, TX
🔬 UDNHarvard/MGH UDN Clinical Site ↗
Massachusetts General Hospital
📍 Boston, MA
🏥 NORDMayo Clinic Center for Individualized Medicine ↗
Mayo Clinic
📍 Rochester, MN
👤 Mayo Clinic Center for Individualized Medicine
🏥 NORDUCLA Rare Disease Day Program ↗
UCLA Health
📍 Los Angeles, CA
Travel Grants
No travel grants are currently matched to Supernumerary breasts.
Community
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Start the conversation →Latest news about Supernumerary breasts
Disease timeline:
New recruiting trial: Sensitivity of Organoids to Predict Treatment Outcome in Breast Cancer Metastases
A new clinical trial is recruiting patients for Supernumerary breasts
New recruiting trial: Motiva Flora Tissue Expander PMCF
A new clinical trial is recruiting patients for Supernumerary breasts
Caregiver Resources
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Family & Caregiver Grants
Financial assistance programs specifically for caregivers of rare disease patients.
Social Security Disability
Learn how rare disease patients may qualify for SSDI/SSI benefits.
Common questions about Supernumerary breasts
What is Supernumerary breasts?
Supernumerary breasts, also known as polymastia or accessory breasts, is a congenital condition in which one or more additional breast tissues develop along the embryonic mammary ridge (milk line), which extends from the axilla (armpit) to the groin on both sides of the body. This condition results from incomplete regression of the mammary ridge during fetal development. The extra breast tissue may range from a small amount of glandular tissue without a visible nipple to a fully formed accessory breast with a nipple and areola. The most common location for supernumerary breasts is the axillary
At what age does Supernumerary breasts typically begin?
Typical onset of Supernumerary breasts is neonatal. Age of onset can vary across affected individuals.
Which specialists treat Supernumerary breasts?
20 specialists and care centers treating Supernumerary breasts are listed on UniteRare, sourced from ClinicalTrials.gov principal investigators, published research, and the NPPES NPI registry.