What is Short stature, Brussels type?
Short stature, Brussels type does not yet have FDA-approved treatments tracked on UniteRare.
Also known as:
Key symptoms:
Short stature (being much shorter than expected)Flat faceSmall nose with a flat nasal bridgeUnderdeveloped cheekbonesShort hands and feetLoose or overly flexible jointsSkeletal abnormalitiesDelayed bone developmentBroad or short fingersMild intellectual disability in some cases
Clinical phenotype terms (10)— hover any for plain English
- Delayed epiphyseal ossificationHP:0002663
- Calcification of cartilageHP:0100593
- Inheritance
- Autosomal recessive
- Passed on when both parents carry the same gene change; often skips generations
- Age of Onset
- Childhood
- Begins in childhood, roughly ages 1 to 12
Treatments
Source: openFDA + DailyMed · NDA / BLA labels with structured indications · refreshed weekly
No FDA-approved treatments are currently listed for Short stature, Brussels type.
View clinical trials →Clinical Trials
View all trials with filters →Source: ClinicalTrials.gov · synced daily · phases, status, and PI names normalized at ingest
No actively recruiting trials found for Short stature, Brussels type at this time.
New trials open frequently. Follow this disease to get notified.
Specialists
View all specialists →Source: NPI Registry + PubMed · trial PI roles cross-referenced with ClinicalTrials.gov · ranked by match score (publications + PI activity + community signal)
No specialists are currently listed for Short stature, Brussels type.
Treatment Centers
8 centersSource: NORD Rare Disease Centers + NIH Undiagnosed Diseases Network (UDN) · centers verified active within last 12 months
Children's Hospital Colorado Rare Disease Program ↗
Children's Hospital Colorado
📍 Aurora, CO
👤 Boston Children's Hospital Rare Disease Program
🔬 UDNHarvard/MGH UDN Clinical Site ↗
Massachusetts General Hospital
📍 Boston, MA
🏥 NORDBoston Children's Hospital Rare Disease Program ↗
Boston Children's Hospital
📍 Boston, MA
👤 Boston Children's Hospital Rare Disease Program
🏥 NORDUCLA Rare Disease Day Program ↗
UCLA Health
📍 Los Angeles, CA
🏨 Children'sAnn & Robert H. Lurie Children's Hospital Genetics ↗
Lurie Children's Hospital
📍 Chicago, IL
👤 Boston Children's Hospital Rare Disease Program
🏥 NORDCincinnati Children's Hospital Medical Center ↗
Cincinnati Children's
📍 Cincinnati, OH
👤 Boston Children's Hospital Rare Disease Program
🏨 Children'sNationwide Children's Hospital Rare Disease Center ↗
Nationwide Children's Hospital
📍 Columbus, OH
👤 Boston Children's Hospital Rare Disease Program
🔬 UDNNIH Clinical Center Undiagnosed Diseases Program ↗
National Institutes of Health
📍 Bethesda, MD
Travel Grants
No travel grants are currently matched to Short stature, Brussels type.
Community
No community posts yet. Be the first to share your experience with Short stature, Brussels type.
Start the conversation →Latest news about Short stature, Brussels type
Source: PubMed + NIH RePORTER + openFDA + clinical-journal RSS · last 30 days · disease-tagged at ingest by AI extraction with human QC
No recent news articles for Short stature, Brussels type.
Follow this condition to be notified when news becomes available.
Caregiver Resources
NORD Caregiver Resources
Support, advocacy, and financial assistance for caregivers of rare disease patients.
Mental Health Support
Rare disease caregiving can be isolating. Connect with counseling and peer support.
Family & Caregiver Grants
Financial assistance programs specifically for caregivers of rare disease patients.
Social Security Disability
Learn how rare disease patients may qualify for SSDI/SSI benefits.
Questions for your doctor
Bring these to your next appointment
- Q1.What specific tests can confirm this diagnosis in my child?,Should we pursue genetic testing, and what might it tell us?,Is growth hormone therapy an option for my child?,What specialists should be part of our care team?,How often should we monitor growth and bone development?,Are there any complications we should watch for as my child grows?,What resources or support groups are available for families with rare skeletal conditions?
Common questions about Short stature, Brussels type
What is Short stature, Brussels type?
Short stature, Brussels type is an extremely rare genetic condition first described in patients from Brussels, Belgium. This condition is characterized by short stature (being significantly shorter than expected for age and sex), along with distinctive facial features and skeletal abnormalities. People with this condition may have a flat face, a small nose with a flat bridge, and underdeveloped cheekbones. The bones and joints can also be affected, with findings such as short hands and feet, joint looseness (hypermobility), and changes in the shape of the spine or other bones. Because this co
How is Short stature, Brussels type inherited?
Short stature, Brussels type follows a autosomal recessive inheritance pattern. Genetic counseling can help families understand recurrence risk and testing options.
At what age does Short stature, Brussels type typically begin?
Typical onset of Short stature, Brussels type is childhood. Age of onset can vary across affected individuals.
Frequently asked questions about Short stature, Brussels type
Auto-generated from canonical disease facts (Orphanet, OMIM, ClinicalTrials.gov, openFDA, NPPES). Not a substitute for clinical guidance.
What is Short stature, Brussels type?
Short stature, Brussels type is a rare disease catalogued in international rare-disease ontologies (Orphanet ORPHA:2867, OMIM 601350). It is typically inherited as autosomal recessive. Age of onset is generally childhood. For verified primary sources, see the UniteRare Short stature, Brussels type page.
How is Short stature, Brussels type inherited?
Short stature, Brussels type follows autosomal recessive inheritance. Genetic counseling is recommended for affected families to understand recurrence risk in offspring and the likelihood of unaffected siblings being carriers. Variants in the underlying gene(s) may be identified via clinical genetic testing.
Are there FDA-approved treatments for Short stature, Brussels type?
Approved treatments for Short stature, Brussels type are tracked from openFDA and DailyMed primary sources. Many rare diseases have no specific FDA-approved therapy; for those, supportive care and management of complications form the basis of clinical care. Orphan-drug-designation status is noted where applicable.
Are there clinical trials for Short stature, Brussels type?
Active clinical trials for Short stature, Brussels type are tracked daily from ClinicalTrials.gov. Trial availability changes frequently; check the UniteRare trial listings for the current count and recruitment status. Sponsors of rare-disease research often welcome inquiries even when a trial is not actively recruiting at a given moment.
How do I find a specialist for Short stature, Brussels type?
Verified Short stature, Brussels type specialists are identified through ClinicalTrials.gov principal-investigator records, peer-reviewed publication authorship (via PubMed), and the NPPES NPI registry. NORD-designated Centers of Excellence and NIH-affiliated rare-disease clinics are also tracked. UniteRare's specialist directory is updated continuously as new evidence becomes available.
See full Short stature, Brussels type page for complete clinical details, sources, and verified-specialist listings.
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