What is Postcardiotomy right ventricular failure?
Postcardiotomy right ventricular failure (also referred to as postcardiotomy right heart failure or post-cardiac surgery right ventricular dysfunction) is a serious complication that occurs following open-heart surgery (cardiotomy). It is characterized by the inability of the right ventricle to adequately pump blood into the pulmonary circulation after a cardiac surgical procedure. This condition can develop after various types of cardiac operations, including coronary artery bypass grafting, valve surgery, heart transplantation, or implantation of a left ventricular assist device. The right ventricle becomes unable to maintain sufficient cardiac output, leading to systemic venous congestion and inadequate blood flow to the lungs. Key clinical features include low cardiac output syndrome, systemic hypotension, elevated central venous pressure, peripheral edema, hepatic congestion, renal dysfunction, and signs of end-organ hypoperfusion. Patients may present with hemodynamic instability requiring vasopressor and inotropic support in the immediate postoperative period. Treatment involves a combination of pharmacological and mechanical support strategies. Inotropic agents (such as milrinone and dobutamine), vasopressors, and pulmonary vasodilators (including inhaled nitric oxide and prostacyclins) are commonly used to optimize right ventricular function and reduce pulmonary vascular resistance. In refractory cases, mechanical circulatory support devices such as right ventricular assist devices (RVAD) or extracorporeal membrane oxygenation (ECMO) may be required. The prognosis depends on the underlying cause, the severity of right ventricular dysfunction, and the timeliness of intervention. This condition carries significant morbidity and mortality and remains a challenging clinical scenario in postoperative cardiac care.
- Age of Onset
- Variable
- Can begin at different ages, from infancy through adulthood
Treatments
Source: openFDA + DailyMed · NDA / BLA labels with structured indications · refreshed weekly
No FDA-approved treatments are currently listed for Postcardiotomy right ventricular failure.
View clinical trials →Clinical Trials
View all trials with filters →Source: ClinicalTrials.gov · synced daily · phases, status, and PI names normalized at ingest
No actively recruiting trials found for Postcardiotomy right ventricular failure at this time.
New trials open frequently. Follow this disease to get notified.
Specialists
View all specialists →Source: NPI Registry + PubMed · trial PI roles cross-referenced with ClinicalTrials.gov · ranked by match score (publications + PI activity + community signal)
No specialists are currently listed for Postcardiotomy right ventricular failure.
Treatment Centers
8 centersSource: NORD Rare Disease Centers + NIH Undiagnosed Diseases Network (UDN) · centers verified active within last 12 months
Children's Hospital Colorado Rare Disease Program ↗
Children's Hospital Colorado
📍 Aurora, CO
👤 Boston Children's Hospital Rare Disease Program
🔬 UDNHarvard/MGH UDN Clinical Site ↗
Massachusetts General Hospital
📍 Boston, MA
🏥 NORDBoston Children's Hospital Rare Disease Program ↗
Boston Children's Hospital
📍 Boston, MA
👤 Boston Children's Hospital Rare Disease Program
🏥 NORDUCLA Rare Disease Day Program ↗
UCLA Health
📍 Los Angeles, CA
🏨 Children'sAnn & Robert H. Lurie Children's Hospital Genetics ↗
Lurie Children's Hospital
📍 Chicago, IL
👤 Boston Children's Hospital Rare Disease Program
🏥 NORDCincinnati Children's Hospital Medical Center ↗
Cincinnati Children's
📍 Cincinnati, OH
👤 Boston Children's Hospital Rare Disease Program
🏨 Children'sNationwide Children's Hospital Rare Disease Center ↗
Nationwide Children's Hospital
📍 Columbus, OH
👤 Boston Children's Hospital Rare Disease Program
🔬 UDNNIH Clinical Center Undiagnosed Diseases Program ↗
National Institutes of Health
📍 Bethesda, MD
Travel Grants
No travel grants are currently matched to Postcardiotomy right ventricular failure.
Community
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Start the conversation →Latest news about Postcardiotomy right ventricular failure
Source: PubMed + NIH RePORTER + openFDA + clinical-journal RSS · last 30 days · disease-tagged at ingest by AI extraction with human QC
No recent news articles for Postcardiotomy right ventricular failure.
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Common questions about Postcardiotomy right ventricular failure
What is Postcardiotomy right ventricular failure?
Postcardiotomy right ventricular failure (also referred to as postcardiotomy right heart failure or post-cardiac surgery right ventricular dysfunction) is a serious complication that occurs following open-heart surgery (cardiotomy). It is characterized by the inability of the right ventricle to adequately pump blood into the pulmonary circulation after a cardiac surgical procedure. This condition can develop after various types of cardiac operations, including coronary artery bypass grafting, valve surgery, heart transplantation, or implantation of a left ventricular assist device. The right
Frequently asked questions about Postcardiotomy right ventricular failure
Auto-generated from canonical disease facts (Orphanet, OMIM, ClinicalTrials.gov, openFDA, NPPES). Not a substitute for clinical guidance.
What is Postcardiotomy right ventricular failure?
Postcardiotomy right ventricular failure is a rare disease catalogued in international rare-disease ontologies (Orphanet ORPHA:263352). Inheritance pattern depends on the specific subtype. Age of onset is generally variable. For verified primary sources, see the UniteRare Postcardiotomy right ventricular failure page.
Are there FDA-approved treatments for Postcardiotomy right ventricular failure?
Approved treatments for Postcardiotomy right ventricular failure are tracked from openFDA and DailyMed primary sources. Many rare diseases have no specific FDA-approved therapy; for those, supportive care and management of complications form the basis of clinical care. Orphan-drug-designation status is noted where applicable.
Are there clinical trials for Postcardiotomy right ventricular failure?
Active clinical trials for Postcardiotomy right ventricular failure are tracked daily from ClinicalTrials.gov. Trial availability changes frequently; check the UniteRare trial listings for the current count and recruitment status. Sponsors of rare-disease research often welcome inquiries even when a trial is not actively recruiting at a given moment.
How do I find a specialist for Postcardiotomy right ventricular failure?
Verified Postcardiotomy right ventricular failure specialists are identified through ClinicalTrials.gov principal-investigator records, peer-reviewed publication authorship (via PubMed), and the NPPES NPI registry. NORD-designated Centers of Excellence and NIH-affiliated rare-disease clinics are also tracked. UniteRare's specialist directory is updated continuously as new evidence becomes available.
See full Postcardiotomy right ventricular failure page for complete clinical details, sources, and verified-specialist listings.
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