Overview
Auriculoocular anomalies-cleft lip syndrome is a very rare condition that was previously listed in medical databases but has since been marked as 'obsolete,' meaning it is no longer recognized as a distinct, separate diagnosis in current medical classification systems. The condition was described as involving a combination of ear (auricular) abnormalities, eye (ocular) abnormalities, and cleft lip — a gap or split in the upper lip that is present from birth. These types of features, when they occur together, are now more likely to be evaluated as part of other recognized syndromes or as overlapping presentations of related conditions. Because this entry has been retired from active use in rare disease registries like Orphanet, detailed clinical information is very limited. If you or a loved one has been given this diagnosis, it is strongly recommended to seek evaluation from a clinical geneticist who can reassess the diagnosis using current classification tools. Modern genetic testing may help identify a more specific underlying cause. Treatment would focus on managing each individual feature — such as surgical repair of cleft lip, hearing support for ear abnormalities, and vision care for eye concerns.
Key symptoms:
Split or gap in the upper lip (cleft lip) present at birthAbnormally shaped or positioned outer earsEye abnormalities present from birthPossible hearing difficulties related to ear structurePossible vision problems related to eye structure
Neonatal
Begins at or shortly after birth (first 4 weeks)
Treatments
No FDA-approved treatments are currently listed for OBSOLETE: Auriculoocular anomalies-cleft lip syndrome.
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Specialists
View all specialists →No specialists are currently listed for OBSOLETE: Auriculoocular anomalies-cleft lip syndrome.
Treatment Centers
8 centersBaylor College of Medicine Rare Disease Center ↗
Baylor College of Medicine
📍 Houston, TX
🏥 NORDStanford Medicine Rare Disease Center ↗
Stanford Medicine
📍 Stanford, CA
🔬 UDNNIH Clinical Center Undiagnosed Diseases Program ↗
National Institutes of Health
📍 Bethesda, MD
🔬 UDNUCLA UDN Clinical Site ↗
UCLA Health
📍 Los Angeles, CA
🔬 UDNBaylor College of Medicine UDN Clinical Site ↗
Baylor College of Medicine
📍 Houston, TX
🔬 UDNHarvard/MGH UDN Clinical Site ↗
Massachusetts General Hospital
📍 Boston, MA
🏥 NORDMayo Clinic Center for Individualized Medicine ↗
Mayo Clinic
📍 Rochester, MN
👤 Mayo Clinic Center for Individualized Medicine
🏥 NORDUCLA Rare Disease Day Program ↗
UCLA Health
📍 Los Angeles, CA
Travel Grants
No travel grants are currently matched to OBSOLETE: Auriculoocular anomalies-cleft lip syndrome.
Community
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Caregiver Resources
NORD Caregiver Resources
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Mental Health Support
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Family & Caregiver Grants
Financial assistance programs specifically for caregivers of rare disease patients.
Social Security Disability
Learn how rare disease patients may qualify for SSDI/SSI benefits.
Questions for your doctor
Bring these to your next appointment
- Q1.Is this diagnosis still considered valid, or should we be looking for a more current diagnosis?,What genetic tests would you recommend to find the underlying cause of these features?,Which specialists should be part of our care team, and how often should we see each one?,When is the best time to consider surgery for the cleft lip and any ear or eye concerns?,Are there any other health problems we should watch for given this combination of features?,What support services are available for speech, hearing, and vision development?,Are there any patient registries or research studies we could participate in?
Common questions about OBSOLETE: Auriculoocular anomalies-cleft lip syndrome
What is OBSOLETE: Auriculoocular anomalies-cleft lip syndrome?
Auriculoocular anomalies-cleft lip syndrome is a very rare condition that was previously listed in medical databases but has since been marked as 'obsolete,' meaning it is no longer recognized as a distinct, separate diagnosis in current medical classification systems. The condition was described as involving a combination of ear (auricular) abnormalities, eye (ocular) abnormalities, and cleft lip — a gap or split in the upper lip that is present from birth. These types of features, when they occur together, are now more likely to be evaluated as part of other recognized syndromes or as overla
At what age does OBSOLETE: Auriculoocular anomalies-cleft lip syndrome typically begin?
Typical onset of OBSOLETE: Auriculoocular anomalies-cleft lip syndrome is neonatal. Age of onset can vary across affected individuals.