What is NON RARE IN EUROPE: Fibromyalgia?
Fibromyalgia is a long-term condition that causes widespread pain throughout the body, along with extreme tiredness and problems with sleep and memory. It is sometimes called fibromyalgia syndrome (FMS). Unlike arthritis, fibromyalgia does not damage joints or tissues — instead, it changes the way the brain and nervous system process pain signals, making the body feel pain more intensely than normal. This is sometimes called 'central sensitization.' The condition affects muscles, tendons, and soft tissues all over the body. People with fibromyalgia often describe a constant dull ache, burning, or stiffness that can shift from place to place. Many also experience headaches, irritable bowel symptoms, anxiety, depression, and a foggy feeling sometimes called 'fibro fog' that makes it hard to concentrate or remember things. There is no cure for fibromyalgia, but many treatments can help manage symptoms. These include medications like duloxetine (Cymbalta), milnacipran (Savella), and pregabalin (Lyrica), which are FDA-approved for fibromyalgia. Exercise, cognitive behavioral therapy (CBT), sleep management, and stress reduction also play a big role in improving quality of life. With the right combination of treatments, many people are able to manage their symptoms and live active lives.
Key symptoms:
Widespread body pain or aching that lasts for monthsExtreme tiredness or fatigue that does not improve with restSleep problems, including waking up feeling unrefreshedMemory and concentration difficulties ('fibro fog')Morning stiffness in muscles and jointsHeadaches or migrainesIrritable bowel syndrome (stomach cramps, bloating, diarrhea or constipation)Sensitivity to touch, light, noise, or temperatureAnxiety or depressionNumbness or tingling in hands and feetPainful menstrual periods in womenRestless legs syndromeJaw pain or temporomandibular joint (TMJ) problems
- Inheritance
- Multifactorial
- Caused by a mix of several genes and environmental factors
- Age of Onset
- Adult
- Begins in adulthood (age 18 or older)
FDA & Trial Timeline
10 eventsVrije Universiteit Brussel — NA
Kanuni Sultan Suleyman Training and Research Hospital
University of California, Irvine — NA
Universidad Francisco de Vitoria — PHASE1
I.R.C.C.S Ospedale Galeazzi-Sant'Ambrogio
Hacettepe University
Kirsehir Ahi Evran Universitesi
Hospital Universitari Vall d'Hebron Research Institute — NA
Data is compiled from FDA regulatory filings and ClinicalTrials.gov, then processed through automated extraction; event classifications and dates may occasionally be misclassified. Verify against the linked FDA filing or trial record before clinical decisions. Updated periodically.
Treatments
Source: openFDA + DailyMed · NDA / BLA labels with structured indications · refreshed weekly
No FDA-approved treatments are currently listed for NON RARE IN EUROPE: Fibromyalgia.
14 clinical trialsare actively recruiting — trials can provide access to cutting-edge therapies.
View clinical trials →Source: ClinicalTrials.gov · synced daily · phases, status, and PI names normalized at ingest
Specialists
View all specialists →Source: NPI Registry + PubMed · trial PI roles cross-referenced with ClinicalTrials.gov · ranked by match score (publications + PI activity + community signal)
No specialists are currently listed for NON RARE IN EUROPE: Fibromyalgia.
Treatment Centers
8 centersSource: NORD Rare Disease Centers + NIH Undiagnosed Diseases Network (UDN) · centers verified active within last 12 months
Children's Hospital Colorado Rare Disease Program ↗
Children's Hospital Colorado
📍 Aurora, CO
👤 Boston Children's Hospital Rare Disease Program
🔬 UDNHarvard/MGH UDN Clinical Site ↗
Massachusetts General Hospital
📍 Boston, MA
🏥 NORDBoston Children's Hospital Rare Disease Program ↗
Boston Children's Hospital
📍 Boston, MA
👤 Boston Children's Hospital Rare Disease Program
🏥 NORDUCLA Rare Disease Day Program ↗
UCLA Health
📍 Los Angeles, CA
🏨 Children'sAnn & Robert H. Lurie Children's Hospital Genetics ↗
Lurie Children's Hospital
📍 Chicago, IL
👤 Boston Children's Hospital Rare Disease Program
🏥 NORDCincinnati Children's Hospital Medical Center ↗
Cincinnati Children's
📍 Cincinnati, OH
👤 Boston Children's Hospital Rare Disease Program
🏨 Children'sNationwide Children's Hospital Rare Disease Center ↗
Nationwide Children's Hospital
📍 Columbus, OH
👤 Boston Children's Hospital Rare Disease Program
🔬 UDNNIH Clinical Center Undiagnosed Diseases Program ↗
National Institutes of Health
📍 Bethesda, MD
Travel Grants
No travel grants are currently matched to NON RARE IN EUROPE: Fibromyalgia.
Community
No community posts yet. Be the first to share your experience with NON RARE IN EUROPE: Fibromyalgia.
Start the conversation →Latest news about NON RARE IN EUROPE: Fibromyalgia
Source: PubMed + NIH RePORTER + openFDA + clinical-journal RSS · last 30 days · disease-tagged at ingest by AI extraction with human QC
No recent news articles for NON RARE IN EUROPE: Fibromyalgia.
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Caregiver Resources
NORD Caregiver Resources
Support, advocacy, and financial assistance for caregivers of rare disease patients.
Mental Health Support
Rare disease caregiving can be isolating. Connect with counseling and peer support.
Family & Caregiver Grants
Financial assistance programs specifically for caregivers of rare disease patients.
Social Security Disability
Learn how rare disease patients may qualify for SSDI/SSI benefits.
Questions for your doctor
Bring these to your next appointment
- Q1.What tests do I need to rule out other conditions that could be causing my symptoms?,Which treatment — medication, therapy, or exercise — should I start with first?,Are there FDA-approved medications for fibromyalgia that might be right for me?,How do I know if my treatment is working, and how long should I give it before trying something else?,What type of exercise is safe for me to start with, given my current pain levels?,Should I see a psychologist or therapist as part of my treatment plan?,Are there any support groups or patient resources you recommend for people with fibromyalgia?
Common questions about NON RARE IN EUROPE: Fibromyalgia
What is NON RARE IN EUROPE: Fibromyalgia?
Fibromyalgia is a long-term condition that causes widespread pain throughout the body, along with extreme tiredness and problems with sleep and memory. It is sometimes called fibromyalgia syndrome (FMS). Unlike arthritis, fibromyalgia does not damage joints or tissues — instead, it changes the way the brain and nervous system process pain signals, making the body feel pain more intensely than normal. This is sometimes called 'central sensitization.' The condition affects muscles, tendons, and soft tissues all over the body. People with fibromyalgia often describe a constant dull ache, burning
How is NON RARE IN EUROPE: Fibromyalgia inherited?
NON RARE IN EUROPE: Fibromyalgia follows a multifactorial inheritance pattern. Genetic counseling can help families understand recurrence risk and testing options.
At what age does NON RARE IN EUROPE: Fibromyalgia typically begin?
Typical onset of NON RARE IN EUROPE: Fibromyalgia is adult. Age of onset can vary across affected individuals.
Are there clinical trials for NON RARE IN EUROPE: Fibromyalgia?
Yes — 14 recruiting clinical trials are currently listed for NON RARE IN EUROPE: Fibromyalgia on UniteRare. See the clinical trials section on this page for phase, sponsor, and site details sourced from ClinicalTrials.gov.
Frequently asked questions about NON RARE IN EUROPE: Fibromyalgia
Auto-generated from canonical disease facts (Orphanet, OMIM, ClinicalTrials.gov, openFDA, NPPES). Not a substitute for clinical guidance.
What is NON RARE IN EUROPE: Fibromyalgia?
NON RARE IN EUROPE: Fibromyalgia is a rare disease catalogued in international rare-disease ontologies (Orphanet ORPHA:41842). It is typically inherited as multifactorial. Age of onset is generally adult. For verified primary sources, see the UniteRare NON RARE IN EUROPE: Fibromyalgia page.
How is NON RARE IN EUROPE: Fibromyalgia inherited?
NON RARE IN EUROPE: Fibromyalgia follows multifactorial inheritance. Genetic counseling is recommended for affected families to understand recurrence risk in offspring and the likelihood of unaffected siblings being carriers. Variants in the underlying gene(s) may be identified via clinical genetic testing.
Are there FDA-approved treatments for NON RARE IN EUROPE: Fibromyalgia?
Approved treatments for NON RARE IN EUROPE: Fibromyalgia are tracked from openFDA and DailyMed primary sources. Many rare diseases have no specific FDA-approved therapy; for those, supportive care and management of complications form the basis of clinical care. Orphan-drug-designation status is noted where applicable.
Are there clinical trials recruiting for NON RARE IN EUROPE: Fibromyalgia?
UniteRare currently lists 14 clinical trials relevant to NON RARE IN EUROPE: Fibromyalgia sourced from ClinicalTrials.gov. Each trial entry includes recruitment status, eligibility criteria summary, principal-investigator information, and study locations. Patients should discuss eligibility with their healthcare provider before enrolling.
How do I find a specialist for NON RARE IN EUROPE: Fibromyalgia?
Verified NON RARE IN EUROPE: Fibromyalgia specialists are identified through ClinicalTrials.gov principal-investigator records, peer-reviewed publication authorship (via PubMed), and the NPPES NPI registry. NORD-designated Centers of Excellence and NIH-affiliated rare-disease clinics are also tracked. UniteRare's specialist directory is updated continuously as new evidence becomes available.
See full NON RARE IN EUROPE: Fibromyalgia page for complete clinical details, sources, and verified-specialist listings.
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