NON RARE IN EUROPE: Anorexia nervosa

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12Active trials8Treatment centers

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What is NON RARE IN EUROPE: Anorexia nervosa?

Anorexia nervosa is a serious eating disorder where a person severely limits how much they eat, often because of an intense fear of gaining weight and a distorted view of their own body. Even when someone is dangerously underweight, they may still see themselves as too heavy. The condition affects the whole body — the heart, bones, hormones, digestive system, and brain can all be harmed by not getting enough nutrition over time. Common signs include extreme weight loss, refusing to eat enough, obsessive thoughts about food and body image, and in people who menstruate, loss of their monthly period. Anorexia nervosa (sometimes called AN) is one of the most medically serious mental health conditions. It has one of the highest death rates of any psychiatric disorder, both from physical complications and from suicide. However, recovery is absolutely possible, especially with early treatment. Treatment usually involves a team of specialists working together — doctors to manage physical health, therapists to address thoughts and emotions, and dietitians to help restore healthy eating. For young people, a family-based approach is often very effective. There is no single medication that cures anorexia, but some medicines can help with related anxiety or depression. The road to recovery can be long, but many people do fully recover and go on to live healthy, fulfilling lives.

Key symptoms:

Extreme weight loss or being significantly underweightRefusing to eat enough food or severely restricting caloriesIntense fear of gaining weight, even when already underweightSeeing yourself as overweight even when you are notLoss of menstrual periods in people who menstruateFeeling cold all the time due to loss of body fatFine downy hair growing on the body (called lanugo) as the body tries to stay warmThinning hair or hair falling outDizziness or fainting, especially when standing upFatigue and weaknessConstipation or stomach painDry or yellowish skinBrittle nailsSwollen cheeks or jaw pain (if purging behaviors are also present)Mood changes, depression, anxiety, or irritability

Inheritance
Multifactorial
Caused by a mix of several genes and environmental factors
Age of Onset
Juvenile
Begins in the teen years
Orphanet ↗NORD ↗

FDA & Trial Timeline

10 events
Jun 2026Building Healthy Eating and Self-Esteem Together for University Students

University of Kansas — NA

TrialRECRUITING
Jul 2025Overview of Knowledge and Practices Among Healthcare Professionals Treating Eating Disorders

University Hospital, Strasbourg, France

TrialRECRUITING
Jul 2025Recovery in Telling Life Stories

University of Aarhus — NA

TrialRECRUITING
Jun 2025Non-invasive Cranial Electrical Stimulation for Mealtime Anxiety in Adults With Eating Disorders

Rogers Behavioral Health — NA

TrialRECRUITING
Jan 2025Diabetes Body Project 2

Joslin Diabetes Center — NA

TrialRECRUITING
Nov 2024Study on the Effectiveness of Journaling as an add-on to Cognitive Behavioral Therapy

University Hospital Tuebingen — NA

TrialENROLLING BY INVITATION
Nov 2024INTERconNEcT-Eds: a Guided Self-help Mobile App to Improve Outcome in Eating Disorders

University of Palermo — NA

TrialRECRUITING
Nov 2024Barrett's Esophagitis in Anorexia Nervosa Binge/Purge Subtype

Denver Health and Hospital Authority

TrialRECRUITING
Jul 2023Precursors of Binge Eating Disorder in a Clinical Sample of Adolescents With Obesity

Fundació Sant Joan de Déu

TrialRECRUITING
May 2023Novel Targetable BIOmarkers in ANorexia NervosA

University Hospital, Basel, Switzerland

TrialRECRUITING

Data is compiled from FDA regulatory filings and ClinicalTrials.gov, then processed through automated extraction; event classifications and dates may occasionally be misclassified. Verify against the linked FDA filing or trial record before clinical decisions. Updated periodically.

Treatments

Source: openFDA + DailyMed · NDA / BLA labels with structured indications · refreshed weekly

No FDA-approved treatments are currently listed for NON RARE IN EUROPE: Anorexia nervosa.

12 clinical trialsare actively recruiting — trials can provide access to cutting-edge therapies.

View clinical trials →

Clinical Trials

12 recruitingView all trials with filters →

Source: ClinicalTrials.gov · synced daily · phases, status, and PI names normalized at ingest

Phase 22 trials
Co-Feedback Action of Growth Hormone, PP and PYY on Ghrelin in Bulimia
Phase 2
Enrolling by Invitation
PI: Kvido Smitka, M.D., Ph.D. (Charles University, Czech Republic) · Age: 18–30 yrs
Transdermal Estrogen in Women With Anorexia Nervosa
Phase 2
Actively Recruiting
PI: Pouneh Fazeli, MD (University of Pittsburgh) · Sites: Pittsburgh, Pennsylvania · Age: 19–45 yrs
N/A6 trials
Non-invasive Cranial Electrical Stimulation for Mealtime Anxiety in Adults With Eating Disorders
N/A
Actively Recruiting
· Sites: Oconomowoc, Wisconsin · Age: 18–30 yrs
INTERconNEcT-Eds: a Guided Self-help Mobile App to Improve Outcome in Eating Disorders
N/A
Actively Recruiting
PI: Gianluca Lo Coco (University of Palermo) · Sites: Catanzaro · Age: 18+ years
Recovery in Telling Life Stories
N/A
Actively Recruiting
PI: Dorthe K. Thomsen, PhD (University of Aarhus) · Sites: Aarhus C · Age: 18–65 yrs
Building Healthy Eating and Self-Esteem Together for University Students
N/A
Actively Recruiting
PI: Kelsie Forbush, PhD (University of Kansas) · Sites: Lawrence, Kansas · Age: 18–65 yrs
Study on the Effectiveness of Journaling as an add-on to Cognitive Behavioral Therapy
N/A
Enrolling by Invitation
PI: Ann-Christine Ehlis, Dr. (University Hospital Tübingen Department of Psychia) · Sites: Tübingen · Age: 18–65 yrs
Diabetes Body Project 2
N/A
Actively Recruiting
PI: Christine Slyne · Sites: Boston, Massachusetts · Age: 18–40 yrs
Other4 trials
Novel Targetable BIOmarkers in ANorexia NervosA
Actively Recruiting
PI: Katharina Timper, Prof. (University Hospital, Basel, Switzerland) · Sites: Basel · Age: 18–60 yrs
Barrett's Esophagitis in Anorexia Nervosa Binge/Purge Subtype
Actively Recruiting
PI: Allison Nitsch, MD (Denver Health and Hospital Authority) · Sites: Denver, Colorado; Denver, Colorado +1 more · Age: 18–65 yrs
Overview of Knowledge and Practices Among Healthcare Professionals Treating Eating Disorders
Actively Recruiting
· Sites: Strasbourg · Age: 18+ years
Precursors of Binge Eating Disorder in a Clinical Sample of Adolescents With Obesity
Actively Recruiting
PI: Esther Via, PhD (Hospital Sant Joan de Deu) · Sites: Esplugues de Llobregat, Barcelona · Age: 12–16 yrs

Source: NPI Registry + PubMed · trial PI roles cross-referenced with ClinicalTrials.gov · ranked by match score (publications + PI activity + community signal)

No specialists are currently listed for NON RARE IN EUROPE: Anorexia nervosa.

View NORD Rare Disease Centers ↗Undiagnosed Disease Network ↗

Treatment Centers

8 centers

Source: NORD Rare Disease Centers + NIH Undiagnosed Diseases Network (UDN) · centers verified active within last 12 months

🏨 Children's

Children's Hospital Colorado Rare Disease Program

Children's Hospital Colorado

📍 Aurora, CO

👤 Boston Children's Hospital Rare Disease Program

🔬 UDN

Harvard/MGH UDN Clinical Site

Massachusetts General Hospital

📍 Boston, MA

🏥 NORD

Boston Children's Hospital Rare Disease Program

Boston Children's Hospital

📍 Boston, MA

👤 Boston Children's Hospital Rare Disease Program

🏥 NORD

UCLA Rare Disease Day Program

UCLA Health

📍 Los Angeles, CA

🏨 Children's

Ann & Robert H. Lurie Children's Hospital Genetics

Lurie Children's Hospital

📍 Chicago, IL

👤 Boston Children's Hospital Rare Disease Program

🏥 NORD

Cincinnati Children's Hospital Medical Center

Cincinnati Children's

📍 Cincinnati, OH

👤 Boston Children's Hospital Rare Disease Program

🏨 Children's

Nationwide Children's Hospital Rare Disease Center

Nationwide Children's Hospital

📍 Columbus, OH

👤 Boston Children's Hospital Rare Disease Program

🔬 UDN

NIH Clinical Center Undiagnosed Diseases Program

National Institutes of Health

📍 Bethesda, MD

Travel Grants

No travel grants are currently matched to NON RARE IN EUROPE: Anorexia nervosa.

Search all travel grants →NORD Financial Assistance ↗

Community

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Latest news about NON RARE IN EUROPE: Anorexia nervosa

Source: PubMed + NIH RePORTER + openFDA + clinical-journal RSS · last 30 days · disease-tagged at ingest by AI extraction with human QC

No recent news articles for NON RARE IN EUROPE: Anorexia nervosa.

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Caregiver Resources

NORD Caregiver Resources

Support, advocacy, and financial assistance for caregivers of rare disease patients.

Mental Health Support

Rare disease caregiving can be isolating. Connect with counseling and peer support.

Family & Caregiver Grants

Financial assistance programs specifically for caregivers of rare disease patients.

Social Security Disability

Learn how rare disease patients may qualify for SSDI/SSI benefits.

Questions for your doctor

Bring these to your next appointment

  • Q1.What level of care do I need right now — outpatient, day program, or inpatient treatment?,What type of therapy do you recommend for me, and how long will it take?,Are there any dangerous physical complications I need to be treated for right away?,Should I be taking any medications, and what are the benefits and side effects?,How will we know if treatment is working, and what does recovery look like?,What should I do if I feel like I am getting worse or having a crisis?,Are there support groups or resources for my family or caregivers?

Common questions about NON RARE IN EUROPE: Anorexia nervosa

What is NON RARE IN EUROPE: Anorexia nervosa?

Anorexia nervosa is a serious eating disorder where a person severely limits how much they eat, often because of an intense fear of gaining weight and a distorted view of their own body. Even when someone is dangerously underweight, they may still see themselves as too heavy. The condition affects the whole body — the heart, bones, hormones, digestive system, and brain can all be harmed by not getting enough nutrition over time. Common signs include extreme weight loss, refusing to eat enough, obsessive thoughts about food and body image, and in people who menstruate, loss of their monthly per

How is NON RARE IN EUROPE: Anorexia nervosa inherited?

NON RARE IN EUROPE: Anorexia nervosa follows a multifactorial inheritance pattern. Genetic counseling can help families understand recurrence risk and testing options.

At what age does NON RARE IN EUROPE: Anorexia nervosa typically begin?

Typical onset of NON RARE IN EUROPE: Anorexia nervosa is juvenile. Age of onset can vary across affected individuals.

Are there clinical trials for NON RARE IN EUROPE: Anorexia nervosa?

Yes — 12 recruiting clinical trials are currently listed for NON RARE IN EUROPE: Anorexia nervosa on UniteRare. See the clinical trials section on this page for phase, sponsor, and site details sourced from ClinicalTrials.gov.

Frequently asked questions about NON RARE IN EUROPE: Anorexia nervosa

Auto-generated from canonical disease facts (Orphanet, OMIM, ClinicalTrials.gov, openFDA, NPPES). Not a substitute for clinical guidance.

  1. What is NON RARE IN EUROPE: Anorexia nervosa?

    NON RARE IN EUROPE: Anorexia nervosa is a rare disease catalogued in international rare-disease ontologies (Orphanet ORPHA:36297). It is typically inherited as multifactorial. Age of onset is generally juvenile. For verified primary sources, see the UniteRare NON RARE IN EUROPE: Anorexia nervosa page.

  2. How is NON RARE IN EUROPE: Anorexia nervosa inherited?

    NON RARE IN EUROPE: Anorexia nervosa follows multifactorial inheritance. Genetic counseling is recommended for affected families to understand recurrence risk in offspring and the likelihood of unaffected siblings being carriers. Variants in the underlying gene(s) may be identified via clinical genetic testing.

  3. Are there FDA-approved treatments for NON RARE IN EUROPE: Anorexia nervosa?

    Approved treatments for NON RARE IN EUROPE: Anorexia nervosa are tracked from openFDA and DailyMed primary sources. Many rare diseases have no specific FDA-approved therapy; for those, supportive care and management of complications form the basis of clinical care. Orphan-drug-designation status is noted where applicable.

  4. Are there clinical trials recruiting for NON RARE IN EUROPE: Anorexia nervosa?

    UniteRare currently lists 12 clinical trials relevant to NON RARE IN EUROPE: Anorexia nervosa sourced from ClinicalTrials.gov. Each trial entry includes recruitment status, eligibility criteria summary, principal-investigator information, and study locations. Patients should discuss eligibility with their healthcare provider before enrolling.

  5. How do I find a specialist for NON RARE IN EUROPE: Anorexia nervosa?

    Verified NON RARE IN EUROPE: Anorexia nervosa specialists are identified through ClinicalTrials.gov principal-investigator records, peer-reviewed publication authorship (via PubMed), and the NPPES NPI registry. NORD-designated Centers of Excellence and NIH-affiliated rare-disease clinics are also tracked. UniteRare's specialist directory is updated continuously as new evidence becomes available.

See full NON RARE IN EUROPE: Anorexia nervosa page for complete clinical details, sources, and verified-specialist listings.

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