What is Neuhauser anomaly?
Neuhauser anomaly, also known as megalodolichobasilar anomaly or Neuhauser syndrome, is a rare condition involving an abnormality of the blood vessels at the base of the brain. Specifically, it refers to an unusually enlarged and elongated basilar artery, which is one of the main arteries supplying blood to the brain. This condition falls under the broader category of aortic arch anomalies as classified by ICD-10 code Q25.4, though it primarily involves the intracranial vasculature. The enlarged basilar artery can press on nearby brain structures, particularly the cranial nerves, brainstem, and surrounding tissues. This pressure can lead to a range of neurological symptoms including hearing loss, facial numbness or weakness, difficulty swallowing, dizziness, and problems with balance. In some cases, the abnormal artery may also increase the risk of stroke or transient ischemic attacks (mini-strokes) due to altered blood flow patterns. Treatment for Neuhauser anomaly is primarily supportive and symptom-based, as there is no cure for the underlying vascular malformation. Management may include medications to control blood pressure and reduce stroke risk, as well as therapies to address specific neurological symptoms. In rare cases, surgical or endovascular interventions may be considered if there is a significant risk of complications. Regular monitoring with brain imaging is important to track any changes in the artery over time.
Key symptoms:
Hearing lossDizziness or vertigoDifficulty with balanceFacial numbness or tinglingFacial weaknessDifficulty swallowingHeadachesVision problems such as double visionRinging in the ears (tinnitus)Weakness or numbness in arms or legsSpeech difficultiesStroke-like episodes
- Age of Onset
- Variable
- Can begin at different ages, from infancy through adulthood
Treatments
Source: openFDA + DailyMed · NDA / BLA labels with structured indications · refreshed weekly
No FDA-approved treatments are currently listed for Neuhauser anomaly.
View clinical trials →Clinical Trials
View all trials with filters →Source: ClinicalTrials.gov · synced daily · phases, status, and PI names normalized at ingest
No actively recruiting trials found for Neuhauser anomaly at this time.
New trials open frequently. Follow this disease to get notified.
Specialists
View all specialists →Source: NPI Registry + PubMed · trial PI roles cross-referenced with ClinicalTrials.gov · ranked by match score (publications + PI activity + community signal)
No specialists are currently listed for Neuhauser anomaly.
Treatment Centers
8 centersSource: NORD Rare Disease Centers + NIH Undiagnosed Diseases Network (UDN) · centers verified active within last 12 months
Children's Hospital Colorado Rare Disease Program ↗
Children's Hospital Colorado
📍 Aurora, CO
👤 Boston Children's Hospital Rare Disease Program
🔬 UDNHarvard/MGH UDN Clinical Site ↗
Massachusetts General Hospital
📍 Boston, MA
🏥 NORDBoston Children's Hospital Rare Disease Program ↗
Boston Children's Hospital
📍 Boston, MA
👤 Boston Children's Hospital Rare Disease Program
🏥 NORDUCLA Rare Disease Day Program ↗
UCLA Health
📍 Los Angeles, CA
🏨 Children'sAnn & Robert H. Lurie Children's Hospital Genetics ↗
Lurie Children's Hospital
📍 Chicago, IL
👤 Boston Children's Hospital Rare Disease Program
🏥 NORDCincinnati Children's Hospital Medical Center ↗
Cincinnati Children's
📍 Cincinnati, OH
👤 Boston Children's Hospital Rare Disease Program
🏨 Children'sNationwide Children's Hospital Rare Disease Center ↗
Nationwide Children's Hospital
📍 Columbus, OH
👤 Boston Children's Hospital Rare Disease Program
🔬 UDNNIH Clinical Center Undiagnosed Diseases Program ↗
National Institutes of Health
📍 Bethesda, MD
Travel Grants
No travel grants are currently matched to Neuhauser anomaly.
Community
No community posts yet. Be the first to share your experience with Neuhauser anomaly.
Start the conversation →Latest news about Neuhauser anomaly
Source: PubMed + NIH RePORTER + openFDA + clinical-journal RSS · last 30 days · disease-tagged at ingest by AI extraction with human QC
No recent news articles for Neuhauser anomaly.
Follow this condition to be notified when news becomes available.
Caregiver Resources
NORD Caregiver Resources
Support, advocacy, and financial assistance for caregivers of rare disease patients.
Mental Health Support
Rare disease caregiving can be isolating. Connect with counseling and peer support.
Family & Caregiver Grants
Financial assistance programs specifically for caregivers of rare disease patients.
Social Security Disability
Learn how rare disease patients may qualify for SSDI/SSI benefits.
Questions for your doctor
Bring these to your next appointment
- Q1.How large is the basilar artery abnormality, and is it pressing on any brain structures?,What is my risk of stroke or other serious complications?,How often should I have brain imaging to monitor the condition?,What medications should I take to reduce my risk of complications?,Are there any activities or lifestyle changes I should avoid?,What symptoms should prompt me to seek emergency care?,Should my family members be screened for this condition?
Common questions about Neuhauser anomaly
What is Neuhauser anomaly?
Neuhauser anomaly, also known as megalodolichobasilar anomaly or Neuhauser syndrome, is a rare condition involving an abnormality of the blood vessels at the base of the brain. Specifically, it refers to an unusually enlarged and elongated basilar artery, which is one of the main arteries supplying blood to the brain. This condition falls under the broader category of aortic arch anomalies as classified by ICD-10 code Q25.4, though it primarily involves the intracranial vasculature. The enlarged basilar artery can press on nearby brain structures, particularly the cranial nerves, brainstem, a
Frequently asked questions about Neuhauser anomaly
Auto-generated from canonical disease facts (Orphanet, OMIM, ClinicalTrials.gov, openFDA, NPPES). Not a substitute for clinical guidance.
What is Neuhauser anomaly?
Neuhauser anomaly is a rare disease catalogued in international rare-disease ontologies (Orphanet ORPHA:99078). Inheritance pattern depends on the specific subtype. Age of onset is generally variable. For verified primary sources, see the UniteRare Neuhauser anomaly page.
Are there FDA-approved treatments for Neuhauser anomaly?
Approved treatments for Neuhauser anomaly are tracked from openFDA and DailyMed primary sources. Many rare diseases have no specific FDA-approved therapy; for those, supportive care and management of complications form the basis of clinical care. Orphan-drug-designation status is noted where applicable.
Are there clinical trials for Neuhauser anomaly?
Active clinical trials for Neuhauser anomaly are tracked daily from ClinicalTrials.gov. Trial availability changes frequently; check the UniteRare trial listings for the current count and recruitment status. Sponsors of rare-disease research often welcome inquiries even when a trial is not actively recruiting at a given moment.
How do I find a specialist for Neuhauser anomaly?
Verified Neuhauser anomaly specialists are identified through ClinicalTrials.gov principal-investigator records, peer-reviewed publication authorship (via PubMed), and the NPPES NPI registry. NORD-designated Centers of Excellence and NIH-affiliated rare-disease clinics are also tracked. UniteRare's specialist directory is updated continuously as new evidence becomes available.
See full Neuhauser anomaly page for complete clinical details, sources, and verified-specialist listings.
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