What is Nasal dorsum fistula?
Nasal dorsum fistula is a rare congenital anomaly classified among other specified congenital malformations of the face and neck. It presents as an abnormal opening (fistula) or sinus tract along the dorsum (bridge) of the nose, typically noticed at birth or in early childhood. This condition is thought to arise from incomplete closure of embryological structures during nasal development, specifically related to the prenasal space or dermal sinus tracts that form during fusion of the frontonasal process. The fistula may appear as a small pit or opening on the nasal bridge, sometimes with intermittent discharge of mucoid or sebaceous material, and can be associated with a subcutaneous cyst or tract that may extend toward deeper nasal or intracranial structures. Recurrent local infections may occur if the tract becomes obstructed or colonized by bacteria. The primary body system affected is the craniofacial region, specifically the external nose and potentially the underlying nasal cartilage and bone. Treatment is primarily surgical, involving complete excision of the fistulous tract and any associated cyst to prevent recurrence and infection. Preoperative imaging, such as MRI or CT scan, may be recommended to delineate the full extent of the tract and to rule out intracranial extension before surgical intervention. Prognosis after complete surgical excision is generally excellent, with low recurrence rates when the entire tract is removed.
- Inheritance
- Sporadic
- Usually appears on its own, not inherited from a parent
- Age of Onset
- Neonatal
- Begins at or shortly after birth (first 4 weeks)
Treatments
Source: openFDA + DailyMed · NDA / BLA labels with structured indications · refreshed weekly
No FDA-approved treatments are currently listed for Nasal dorsum fistula.
View clinical trials →Clinical Trials
View all trials with filters →Source: ClinicalTrials.gov · synced daily · phases, status, and PI names normalized at ingest
No actively recruiting trials found for Nasal dorsum fistula at this time.
New trials open frequently. Follow this disease to get notified.
Specialists
View all specialists →Source: NPI Registry + PubMed · trial PI roles cross-referenced with ClinicalTrials.gov · ranked by match score (publications + PI activity + community signal)
No specialists are currently listed for Nasal dorsum fistula.
Treatment Centers
8 centersSource: NORD Rare Disease Centers + NIH Undiagnosed Diseases Network (UDN) · centers verified active within last 12 months
Children's Hospital Colorado Rare Disease Program ↗
Children's Hospital Colorado
📍 Aurora, CO
👤 Boston Children's Hospital Rare Disease Program
🔬 UDNHarvard/MGH UDN Clinical Site ↗
Massachusetts General Hospital
📍 Boston, MA
🏥 NORDBoston Children's Hospital Rare Disease Program ↗
Boston Children's Hospital
📍 Boston, MA
👤 Boston Children's Hospital Rare Disease Program
🏥 NORDUCLA Rare Disease Day Program ↗
UCLA Health
📍 Los Angeles, CA
🏨 Children'sAnn & Robert H. Lurie Children's Hospital Genetics ↗
Lurie Children's Hospital
📍 Chicago, IL
👤 Boston Children's Hospital Rare Disease Program
🏥 NORDCincinnati Children's Hospital Medical Center ↗
Cincinnati Children's
📍 Cincinnati, OH
👤 Boston Children's Hospital Rare Disease Program
🏨 Children'sNationwide Children's Hospital Rare Disease Center ↗
Nationwide Children's Hospital
📍 Columbus, OH
👤 Boston Children's Hospital Rare Disease Program
🔬 UDNNIH Clinical Center Undiagnosed Diseases Program ↗
National Institutes of Health
📍 Bethesda, MD
Travel Grants
No travel grants are currently matched to Nasal dorsum fistula.
Community
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Start the conversation →Latest news about Nasal dorsum fistula
Source: PubMed + NIH RePORTER + openFDA + clinical-journal RSS · last 30 days · disease-tagged at ingest by AI extraction with human QC
No recent news articles for Nasal dorsum fistula.
Follow this condition to be notified when news becomes available.
Caregiver Resources
NORD Caregiver Resources
Support, advocacy, and financial assistance for caregivers of rare disease patients.
Mental Health Support
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Family & Caregiver Grants
Financial assistance programs specifically for caregivers of rare disease patients.
Social Security Disability
Learn how rare disease patients may qualify for SSDI/SSI benefits.
Common questions about Nasal dorsum fistula
What is Nasal dorsum fistula?
Nasal dorsum fistula is a rare congenital anomaly classified among other specified congenital malformations of the face and neck. It presents as an abnormal opening (fistula) or sinus tract along the dorsum (bridge) of the nose, typically noticed at birth or in early childhood. This condition is thought to arise from incomplete closure of embryological structures during nasal development, specifically related to the prenasal space or dermal sinus tracts that form during fusion of the frontonasal process. The fistula may appear as a small pit or opening on the nasal bridge, sometimes with inter
How is Nasal dorsum fistula inherited?
Nasal dorsum fistula follows a sporadic inheritance pattern. Genetic counseling can help families understand recurrence risk and testing options.
At what age does Nasal dorsum fistula typically begin?
Typical onset of Nasal dorsum fistula is neonatal. Age of onset can vary across affected individuals.
Frequently asked questions about Nasal dorsum fistula
Auto-generated from canonical disease facts (Orphanet, OMIM, ClinicalTrials.gov, openFDA, NPPES). Not a substitute for clinical guidance.
What is Nasal dorsum fistula?
Nasal dorsum fistula is a rare disease catalogued in international rare-disease ontologies (Orphanet ORPHA:141219). It is typically inherited as sporadic. Age of onset is generally neonatal. For verified primary sources, see the UniteRare Nasal dorsum fistula page.
How is Nasal dorsum fistula inherited?
Nasal dorsum fistula follows sporadic inheritance. Genetic counseling is recommended for affected families to understand recurrence risk in offspring and the likelihood of unaffected siblings being carriers. Variants in the underlying gene(s) may be identified via clinical genetic testing.
Are there FDA-approved treatments for Nasal dorsum fistula?
Approved treatments for Nasal dorsum fistula are tracked from openFDA and DailyMed primary sources. Many rare diseases have no specific FDA-approved therapy; for those, supportive care and management of complications form the basis of clinical care. Orphan-drug-designation status is noted where applicable.
Are there clinical trials for Nasal dorsum fistula?
Active clinical trials for Nasal dorsum fistula are tracked daily from ClinicalTrials.gov. Trial availability changes frequently; check the UniteRare trial listings for the current count and recruitment status. Sponsors of rare-disease research often welcome inquiries even when a trial is not actively recruiting at a given moment.
How do I find a specialist for Nasal dorsum fistula?
Verified Nasal dorsum fistula specialists are identified through ClinicalTrials.gov principal-investigator records, peer-reviewed publication authorship (via PubMed), and the NPPES NPI registry. NORD-designated Centers of Excellence and NIH-affiliated rare-disease clinics are also tracked. UniteRare's specialist directory is updated continuously as new evidence becomes available.
See full Nasal dorsum fistula page for complete clinical details, sources, and verified-specialist listings.
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