Motor stereotypies

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ORPHA:306765
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1Active trials3Specialists8Treatment centers

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UniteRare data is compiled from authoritative primary sources (FDA.gov, ClinicalTrials.gov, Orphanet, OMIM, NORD), then processed through automated and AI-assisted extraction pipelines.
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What is Motor stereotypies?

Motor stereotypies are repetitive, rhythmic, seemingly purposeless movements that a person performs over and over again. Common examples include hand flapping, arm waving, finger wiggling, head nodding, or body rocking. These movements are sometimes called 'primary motor stereotypies' when they occur in otherwise typically developing children, or 'complex motor stereotypies' when they involve more elaborate patterns. They are different from tics, which tend to be more sudden and brief. Motor stereotypies usually begin in early childhood, often before age 3. Children may perform these movements when they are excited, bored, stressed, or deeply focused. The movements are typically suppressible for short periods when the child is made aware of them. Many children with motor stereotypies are otherwise developing normally, though stereotypies can also occur alongside autism spectrum disorder, intellectual disability, or sensory processing differences. The condition is generally not dangerous, but it can cause social embarrassment or interfere with daily activities. Treatment is not always necessary. When treatment is pursued, behavioral therapy — particularly habit reversal training — is the most commonly used approach and has shown good results. There are no FDA-approved medications specifically for motor stereotypies, though some doctors may try certain medications off-label in severe cases. Many children see improvement as they grow older, though some continue to have stereotypies into adulthood.

Key symptoms:

Repetitive hand flappingArm waving or shakingFinger wiggling in front of the faceHead nodding or shakingBody rocking back and forthPacing in patternsHand or wrist movementsJumping or bouncing repeatedlyMovements that increase with excitement or stressMovements that increase with boredom or fatigueAbility to briefly stop the movement when askedMovements that look the same each time they happenSocial embarrassment about the movements

Inheritance
Variable
Can be inherited in different ways depending on the underlying gene
Age of Onset
Childhood
Begins in childhood, roughly ages 1 to 12
Orphanet ↗NORD ↗

FDA & Trial Timeline

1 event
Apr 2025Stereotypic Behaviors and Feeding Difficulties in Adults With Developmental Disabilities

Oslo University Hospital — NA

TrialRECRUITING

Data is compiled from FDA regulatory filings and ClinicalTrials.gov, then processed through automated extraction; event classifications and dates may occasionally be misclassified. Verify against the linked FDA filing or trial record before clinical decisions. Updated periodically.

Treatments

Source: openFDA + DailyMed · NDA / BLA labels with structured indications · refreshed weekly

No FDA-approved treatments are currently listed for Motor stereotypies.

1 clinical trialare actively recruiting — trials can provide access to cutting-edge therapies.

View clinical trials →

Clinical Trials

1 recruitingView all trials with filters →

Source: ClinicalTrials.gov · synced daily · phases, status, and PI names normalized at ingest

N/A1 trial
Stereotypic Behaviors and Feeding Difficulties in Adults With Developmental Disabilities
N/A
Actively Recruiting
PI: Petur I Petursson, MS, BCBA (Oslo University Hospital) · Sites: Oslo, Oslo County · Age: 18+ years

Specialists

3 foundView all specialists →

Source: NPI Registry + PubMed · trial PI roles cross-referenced with ClinicalTrials.gov · ranked by match score (publications + PI activity + community signal)

PB
Petur I Petursson, MS, BCBA
Specialist
PI on 1 active trial
BM
Beth A Belluscio, M.D.
Specialist
PI on 1 active trial
KD
Karl M Newell, Ph. D.
Specialist
PI on 1 active trial2 Motor stereotypies publications

Treatment Centers

8 centers

Source: NORD Rare Disease Centers + NIH Undiagnosed Diseases Network (UDN) · centers verified active within last 12 months

🏨 Children's

Children's Hospital Colorado Rare Disease Program

Children's Hospital Colorado

📍 Aurora, CO

👤 Boston Children's Hospital Rare Disease Program

🔬 UDN

Harvard/MGH UDN Clinical Site

Massachusetts General Hospital

📍 Boston, MA

🏥 NORD

Boston Children's Hospital Rare Disease Program

Boston Children's Hospital

📍 Boston, MA

👤 Boston Children's Hospital Rare Disease Program

🏥 NORD

UCLA Rare Disease Day Program

UCLA Health

📍 Los Angeles, CA

🏨 Children's

Ann & Robert H. Lurie Children's Hospital Genetics

Lurie Children's Hospital

📍 Chicago, IL

👤 Boston Children's Hospital Rare Disease Program

🏥 NORD

Cincinnati Children's Hospital Medical Center

Cincinnati Children's

📍 Cincinnati, OH

👤 Boston Children's Hospital Rare Disease Program

🏨 Children's

Nationwide Children's Hospital Rare Disease Center

Nationwide Children's Hospital

📍 Columbus, OH

👤 Boston Children's Hospital Rare Disease Program

🔬 UDN

NIH Clinical Center Undiagnosed Diseases Program

National Institutes of Health

📍 Bethesda, MD

Travel Grants

No travel grants are currently matched to Motor stereotypies.

Search all travel grants →NORD Financial Assistance ↗

Community

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Latest news about Motor stereotypies

Source: PubMed + NIH RePORTER + openFDA + clinical-journal RSS · last 30 days · disease-tagged at ingest by AI extraction with human QC

Disease timeline:

New recruiting trial: Stereotypic Behaviors and Feeding Difficulties in Adults With Developmental Disabilities

A new clinical trial is recruiting patients for Motor stereotypies

Caregiver Resources

NORD Caregiver Resources

Support, advocacy, and financial assistance for caregivers of rare disease patients.

Mental Health Support

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Family & Caregiver Grants

Financial assistance programs specifically for caregivers of rare disease patients.

Social Security Disability

Learn how rare disease patients may qualify for SSDI/SSI benefits.

Questions for your doctor

Bring these to your next appointment

  • Q1.Are these movements stereotypies, tics, or something else?,Should my child be evaluated for autism spectrum disorder or other developmental conditions?,Does my child need any brain imaging or EEG testing?,Would behavioral therapy like habit reversal training be helpful for my child?,Can you recommend a therapist experienced in treating motor stereotypies?,Are there any medications that might help if behavioral therapy is not enough?,Will my child outgrow these movements over time?

Common questions about Motor stereotypies

What is Motor stereotypies?

Motor stereotypies are repetitive, rhythmic, seemingly purposeless movements that a person performs over and over again. Common examples include hand flapping, arm waving, finger wiggling, head nodding, or body rocking. These movements are sometimes called 'primary motor stereotypies' when they occur in otherwise typically developing children, or 'complex motor stereotypies' when they involve more elaborate patterns. They are different from tics, which tend to be more sudden and brief. Motor stereotypies usually begin in early childhood, often before age 3. Children may perform these movement

At what age does Motor stereotypies typically begin?

Typical onset of Motor stereotypies is childhood. Age of onset can vary across affected individuals.

Are there clinical trials for Motor stereotypies?

Yes — 1 recruiting clinical trial is currently listed for Motor stereotypies on UniteRare. See the clinical trials section on this page for phase, sponsor, and site details sourced from ClinicalTrials.gov.

Which specialists treat Motor stereotypies?

3 specialists and care centers treating Motor stereotypies are listed on UniteRare, sourced from ClinicalTrials.gov principal investigators, published research, and the NPPES NPI registry.

Frequently asked questions about Motor stereotypies

Auto-generated from canonical disease facts (Orphanet, OMIM, ClinicalTrials.gov, openFDA, NPPES). Not a substitute for clinical guidance.

  1. What is Motor stereotypies?

    Motor stereotypies is a rare disease catalogued in international rare-disease ontologies (Orphanet ORPHA:306765). It is typically inherited as variable. Age of onset is generally childhood. For verified primary sources, see the UniteRare Motor stereotypies page.

  2. How is Motor stereotypies inherited?

    Motor stereotypies follows variable inheritance. Genetic counseling is recommended for affected families to understand recurrence risk in offspring and the likelihood of unaffected siblings being carriers. Variants in the underlying gene(s) may be identified via clinical genetic testing.

  3. Are there FDA-approved treatments for Motor stereotypies?

    Approved treatments for Motor stereotypies are tracked from openFDA and DailyMed primary sources. Many rare diseases have no specific FDA-approved therapy; for those, supportive care and management of complications form the basis of clinical care. Orphan-drug-designation status is noted where applicable.

  4. Are there clinical trials recruiting for Motor stereotypies?

    UniteRare currently lists 1 clinical trial relevant to Motor stereotypies sourced from ClinicalTrials.gov. Each trial entry includes recruitment status, eligibility criteria summary, principal-investigator information, and study locations. Patients should discuss eligibility with their healthcare provider before enrolling.

  5. How do I find a specialist for Motor stereotypies?

    UniteRare lists 3 verified clinicians with documented expertise in Motor stereotypies, sourced from ClinicalTrials.gov principal-investigator records, PubMed publication histories, and the NPPES NPI registry. Filter by state or browse our state-specific specialist pages for nearby options.

See full Motor stereotypies page for complete clinical details, sources, and verified-specialist listings.

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