Marburg hemorrhagic fever

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ORPHA:99826A98.3
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2FDA treatments1Active trials10Specialists8Treatment centers2Financial resources

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ℹ
UniteRare data is sourced from FDA.gov, ClinicalTrials.gov, Orphanet, OMIM, and NORD.
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Overview

Also known as:

Green monkey diseaseMHFMarburg virus disease

Clinical phenotype terms— hover any for plain English:

Abnormality of the coagulation cascadeHP:0003256Internal hemorrhageHP:0011029Atypical absence status epilepticusHP:0011151Subconjunctival hemorrhageHP:0011896Bloody diarrheaHP:0025085Excessive bleeding after a venipunctureHP:0030139Nonproductive coughHP:0031246ShockHP:0031273
Orphanet ↗NORD ↗

FDA & Trial Timeline

5 events
Mar 2026A Phase 1 Randomized, Observer-blind, Placebo-controlled, Dose-escalation Clinical Trial to Evaluate the Safety and Immunogenicity of rVSV∆G-MARV-GP Vaccine in Adults in Good General Health

International AIDS Vaccine Initiative — PHASE1

TrialNOT YET RECRUITING
Jan 2026ZYCUBO: FDA approved
FDAcompleted
Apr 2025A Trial to Evaluate Safety, Tolerability, and Immune Responses of an Investigational Monovalent Chimpanzee Adenoviral Vectored Marburg Virus Vaccine in Healthy Adults

Albert B. Sabin Vaccine Institute — PHASE2

TrialACTIVE NOT RECRUITING
Nov 2024F18-MHF: Orthopedic Implants-Associated Infection Detection

Emory University

TrialRECRUITING
Apr 2014Ultra Hypofractionnated Radiotherapy With HDR Brachytherapy Boost.

CHU de Quebec-Universite Laval — NA

TrialRECRUITING

Data sourced from FDA regulatory filings and ClinicalTrials.gov. Updated periodically.

Treatments

2 available

Zycubo

copper histidinate· Sentynl Therapeutics, Inc.Orphan Drug

treatment of Menkes disease in pediatric patients

View Details →FDA Label ↗Copay Card ↗Patient Assistance ↗

XIAFLEX

collagenase clostridium histolyticum· Auxilium Pharmaceuticals, Inc.■ Boxed WarningOrphan Drug

Treatment of adult men with Peyronie's disease with a palpable plaque and curvature deformity of at least 30 degrees at the start of therapy.

View Details →FDA Label ↗Copay Card ↗Patient Assistance ↗

Clinical Trials

1 recruitingView all trials with filters →
Phase 21 trial
A Trial to Evaluate Safety, Tolerability, and Immune Responses of an Investigational Monovalent Chimpanzee Adenoviral Vectored Marburg Virus Vaccine in Healthy Adults
Phase 2
Active
· Sites: Huntsville, Alabama; Phoenix, Arizona +5 more · Age: 18–70 yrs
View on ClinicalTrials.gov ↗I'm interested →

Specialists

10 foundView all specialists →
HM
Hannah Kibuuka, MBChB, MMed, MPH
Specialist
PI on 1 active trial
AM
Alison Heald, MD
SEATTLE, WA
Specialist
PI on 4 active trials1 Marburg hemorrhagic fever publication
AM
Apinya B Vutikullird, MD
CYPRESS, CA
Specialist
PI on 1 active trial1 Marburg hemorrhagic fever publication
MM
Melinda Hamer, M.D.
Specialist
PI on 1 active trial
MM
Michael Stevenson, MD
Specialist
PI on 1 active trial
RM
Richard Kenney, MD
Specialist
PI on 3 active trials
MM
Mohamed Al-Ibrahim, MD
BALTIMORE, MD
Specialist
PI on 3 active trials
DM
David Hoover, MD
Specialist
PI on 1 active trial
DP
Daniel Dickerson, MD, PhD
Specialist
PI on 1 active trial
TM
Tuan Le, MD
Specialist
PI on 1 active trial

Treatment Centers

8 centers
🏥 NORD

Baylor College of Medicine Rare Disease Center ↗

Baylor College of Medicine

📍 Houston, TX

🏥 NORD

Stanford Medicine Rare Disease Center ↗

Stanford Medicine

📍 Stanford, CA

🔬 UDN

NIH Clinical Center Undiagnosed Diseases Program ↗

National Institutes of Health

📍 Bethesda, MD

🔬 UDN

UCLA UDN Clinical Site ↗

UCLA Health

📍 Los Angeles, CA

🔬 UDN

Baylor College of Medicine UDN Clinical Site ↗

Baylor College of Medicine

📍 Houston, TX

🔬 UDN

Harvard/MGH UDN Clinical Site ↗

Massachusetts General Hospital

📍 Boston, MA

🏥 NORD

Mayo Clinic Center for Individualized Medicine ↗

Mayo Clinic

📍 Rochester, MN

👤 Mayo Clinic Center for Individualized Medicine

🏥 NORD

UCLA Rare Disease Day Program ↗

UCLA Health

📍 Los Angeles, CA

Financial Resources

2 resources
Zycubo(copper histidinate)— Sentynl Therapeutics, Inc.
XIAFLEX(collagenase clostridium histolyticum)— Auxilium Pharmaceuticals, Inc.

Travel Grants

No travel grants are currently matched to Marburg hemorrhagic fever.

Search all travel grants →NORD Financial Assistance ↗

Community

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Latest news about Marburg hemorrhagic fever

Disease timeline:

New recruiting trial: Ultra Hypofractionnated Radiotherapy With HDR Brachytherapy Boost.

A new clinical trial is recruiting patients for Marburg hemorrhagic fever

New recruiting trial: F18-MHF: Orthopedic Implants-Associated Infection Detection

A new clinical trial is recruiting patients for Marburg hemorrhagic fever

Caregiver Resources

NORD Caregiver Resources

Support, advocacy, and financial assistance for caregivers of rare disease patients.

Mental Health Support

Rare disease caregiving can be isolating. Connect with counseling and peer support.

Family & Caregiver Grants

Financial assistance programs specifically for caregivers of rare disease patients.

Social Security Disability

Learn how rare disease patients may qualify for SSDI/SSI benefits.

Common questions about Marburg hemorrhagic fever

Are there clinical trials for Marburg hemorrhagic fever?

Yes — 1 recruiting clinical trial is currently listed for Marburg hemorrhagic fever on UniteRare. See the clinical trials section on this page for phase, sponsor, and site details sourced from ClinicalTrials.gov.

Which specialists treat Marburg hemorrhagic fever?

10 specialists and care centers treating Marburg hemorrhagic fever are listed on UniteRare, sourced from ClinicalTrials.gov principal investigators, published research, and the NPPES NPI registry.

What treatment and support options exist for Marburg hemorrhagic fever?

1 patient support program are currently tracked on UniteRare for Marburg hemorrhagic fever. See the treatments and support programs sections for copay assistance, eligibility, and contact details.