What is Klinefelter Syndrome?
Klinefelter Syndrome is treated with 1 medication in our database, including Jatenzo. 1 of these has manufacturer assistance programs available to help reduce out-of-pocket costs. Medications are manufactured by Tolmar. Patients and caregivers can find copay cards, patient assistance programs, and travel grants for Klinefelter Syndrome treatment below.
- Inheritance
- Sporadic
- Usually appears on its own, not inherited from a parent
- Age of Onset
- Variable
- Can begin at different ages, from infancy through adulthood
FDA & Trial Timeline
1 eventGeorgios Papadakis — PHASE3
Data is compiled from FDA regulatory filings and ClinicalTrials.gov, then processed through automated extraction; event classifications and dates may occasionally be misclassified. Verify against the linked FDA filing or trial record before clinical decisions. Updated periodically.
Treatments
0 FDA-approved · 1 other trackedSource: openFDA + DailyMed · NDA / BLA labels with structured indications · refreshed weekly
Other tracked therapies (1)
Medications tracked in our therapeutics database that are not FDA-approved for Klinefelter Syndrome via a labelled indication. May include investigational, off-label, or supportive therapies. Always verify with a clinician before use.
Jatenzo
* Patient Copay Amount: As little as $0 per month for eligible patients with commercial insurance. * Maximum Annual Benefit Limit: Not Publicly Available (The program covers up to $393 for a 1-month s
Source: ClinicalTrials.gov · synced daily · phases, status, and PI names normalized at ingest
Source: NPI Registry + PubMed · trial PI roles cross-referenced with ClinicalTrials.gov · ranked by match score (publications + PI activity + community signal)
Specialty unconfirmed
University College London Hospitals NHS Foundation Trust
Specialty unconfirmed
University College London Hospitals NHS Foundation Trust
Specialty unconfirmed
University College London Hospitals NHS Foundation Trust
Rare Disease Specialist
Service of Endocrinology, Diabetes & Metabolism
Specialty unconfirmed
Alder Hey Children's Hospital
Specialty unconfirmed
Aarhus University Hospital
Specialty unconfirmed
Sapienza University of Rome
Specialty unconfirmed
University College London Hospitals
Specialty unconfirmed
Alder Hey Children's Hospital
Specialty unconfirmed
Alder Hey Children's Hospital
Specialty unconfirmed
University Hospital of Padova
Specialty unconfirmed
Alder Hey Children's Hospital
Specialty unconfirmed
Sapienza University of Rome
Specialty unconfirmed
University College London Hospitals NHS Foundation Trust
Specialty unconfirmed
Liverpool Women's NHS Foundation Trust
Specialty unconfirmed
Centrum für Reproduktionsmedizin und Andrologie/klinische Andrologie
Treatment Centers
8 centersSource: NORD Rare Disease Centers + NIH Undiagnosed Diseases Network (UDN) · centers verified active within last 12 months
Children's Hospital Colorado Rare Disease Program ↗
Children's Hospital Colorado
📍 Aurora, CO
👤 Boston Children's Hospital Rare Disease Program
🔬 UDNHarvard/MGH UDN Clinical Site ↗
Massachusetts General Hospital
📍 Boston, MA
🏥 NORDBoston Children's Hospital Rare Disease Program ↗
Boston Children's Hospital
📍 Boston, MA
👤 Boston Children's Hospital Rare Disease Program
🏥 NORDUCLA Rare Disease Day Program ↗
UCLA Health
📍 Los Angeles, CA
🏨 Children'sAnn & Robert H. Lurie Children's Hospital Genetics ↗
Lurie Children's Hospital
📍 Chicago, IL
👤 Boston Children's Hospital Rare Disease Program
🏥 NORDCincinnati Children's Hospital Medical Center ↗
Cincinnati Children's
📍 Cincinnati, OH
👤 Boston Children's Hospital Rare Disease Program
🏨 Children'sNationwide Children's Hospital Rare Disease Center ↗
Nationwide Children's Hospital
📍 Columbus, OH
👤 Boston Children's Hospital Rare Disease Program
🔬 UDNNIH Clinical Center Undiagnosed Diseases Program ↗
National Institutes of Health
📍 Bethesda, MD
Travel Grants
No travel grants are currently matched to Klinefelter Syndrome.
Community
No community posts yet. Be the first to share your experience with Klinefelter Syndrome.
Start the conversation →Latest news about Klinefelter Syndrome
Source: PubMed + NIH RePORTER + openFDA + clinical-journal RSS · last 30 days · disease-tagged at ingest by AI extraction with human QC
Disease timeline:
New trial: Sex Steroids Balance for Metabolic and Reproductive Health in Klinefelter Syndrome
Phase PHASE3 trial recruiting. Anastrozole
Caregiver Resources
NORD Caregiver Resources
Support, advocacy, and financial assistance for caregivers of rare disease patients.
Mental Health Support
Rare disease caregiving can be isolating. Connect with counseling and peer support.
Family & Caregiver Grants
Financial assistance programs specifically for caregivers of rare disease patients.
Social Security Disability
Learn how rare disease patients may qualify for SSDI/SSI benefits.
Common questions about Klinefelter Syndrome
What is Klinefelter Syndrome?
Klinefelter Syndrome is treated with 1 medication in our database, including Jatenzo. 1 of these has manufacturer assistance programs available to help reduce out-of-pocket costs. Medications are manufactured by Tolmar. Patients and caregivers can find copay cards, patient assistance programs, and travel grants for Klinefelter Syndrome treatment below.
How is Klinefelter Syndrome inherited?
Klinefelter Syndrome follows a sporadic inheritance pattern. Genetic counseling can help families understand recurrence risk and testing options.
Are there clinical trials for Klinefelter Syndrome?
Yes — 1 recruiting clinical trial is currently listed for Klinefelter Syndrome on UniteRare. See the clinical trials section on this page for phase, sponsor, and site details sourced from ClinicalTrials.gov.
Which specialists treat Klinefelter Syndrome?
16 specialists and care centers treating Klinefelter Syndrome are listed on UniteRare, sourced from ClinicalTrials.gov principal investigators, published research, and the NPPES NPI registry.
What treatment and support options exist for Klinefelter Syndrome?
1 FDA-approved treatment are currently tracked on UniteRare for Klinefelter Syndrome. See the treatments and support programs sections for copay assistance, eligibility, and contact details.
Frequently asked questions about Klinefelter Syndrome
Auto-generated from canonical disease facts (Orphanet, OMIM, ClinicalTrials.gov, openFDA, NPPES). Not a substitute for clinical guidance.
What is Klinefelter Syndrome?
Klinefelter Syndrome is a rare disease catalogued in international rare-disease ontologies. It is typically inherited as sporadic. Age of onset is generally variable. For verified primary sources, see the UniteRare Klinefelter Syndrome page.
How is Klinefelter Syndrome inherited?
Klinefelter Syndrome follows sporadic inheritance. Genetic counseling is recommended for affected families to understand recurrence risk in offspring and the likelihood of unaffected siblings being carriers. Variants in the underlying gene(s) may be identified via clinical genetic testing.
Are there FDA-approved treatments for Klinefelter Syndrome?
Yes — UniteRare tracks 1 FDA-approved treatment with indications relevant to Klinefelter Syndrome. Each entry includes prescribing information, orphan-drug-designation status where applicable, and the FDA application number for verification.
Are there clinical trials recruiting for Klinefelter Syndrome?
UniteRare currently lists 1 clinical trial relevant to Klinefelter Syndrome sourced from ClinicalTrials.gov. Each trial entry includes recruitment status, eligibility criteria summary, principal-investigator information, and study locations. Patients should discuss eligibility with their healthcare provider before enrolling.
How do I find a specialist for Klinefelter Syndrome?
UniteRare lists 16 verified clinicians with documented expertise in Klinefelter Syndrome, sourced from ClinicalTrials.gov principal-investigator records, PubMed publication histories, and the NPPES NPI registry. Filter by state or browse our state-specific specialist pages for nearby options.
See full Klinefelter Syndrome page for complete clinical details, sources, and verified-specialist listings.
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