Overview
Genetic tumor of hematopoietic and lymphoid tissues is a broad category of rare cancers that arise in the blood-forming (hematopoietic) and immune system (lymphoid) cells due to inherited genetic changes. Unlike most blood cancers that develop from random mutations over a lifetime, these tumors have a genetic basis, meaning a person is born with or inherits gene changes that significantly increase their risk of developing these cancers. The blood and immune system are affected, which can lead to problems with normal blood cell production, immune function, and the growth of abnormal cells in the bone marrow, lymph nodes, spleen, and other organs. Symptoms can vary widely depending on the specific type of tumor but often include unexplained fatigue, frequent infections, easy bruising or bleeding, swollen lymph nodes, fevers, night sweats, and unintended weight loss. Some people may have enlarged spleens or livers. Because these conditions have a genetic component, multiple family members may be affected across generations. Treatment depends on the specific subtype and may include chemotherapy, targeted therapies, immunotherapy, radiation, and stem cell (bone marrow) transplantation. Advances in genetic testing have improved the ability to identify at-risk individuals early and tailor treatments. Ongoing research continues to uncover new targeted therapies that address the specific genetic drivers of these tumors.
Key symptoms:
Unexplained fatigue and weaknessFrequent or severe infectionsEasy bruising or unusual bleedingSwollen lymph nodesUnexplained feversNight sweatsUnintended weight lossEnlarged spleen or liverBone or joint painPale skin or anemiaShortness of breathSkin rashes or lumpsFeeling full quickly due to enlarged organsRecurrent nosebleeds or bleeding gums
Variable
Can be inherited in different ways depending on the underlying gene
Variable
Can begin at different ages, from infancy through adulthood
Treatments
No FDA-approved treatments are currently listed for Genetic tumor of hematopoietic and lymphoid tissues.
View clinical trials →Clinical Trials
View all trials with filters →No actively recruiting trials found for Genetic tumor of hematopoietic and lymphoid tissues at this time.
New trials open frequently. Follow this disease to get notified.
Treatment Centers
8 centersBaylor College of Medicine Rare Disease Center ↗
Baylor College of Medicine
📍 Houston, TX
🏥 NORDStanford Medicine Rare Disease Center ↗
Stanford Medicine
📍 Stanford, CA
🔬 UDNNIH Clinical Center Undiagnosed Diseases Program ↗
National Institutes of Health
📍 Bethesda, MD
🔬 UDNUCLA UDN Clinical Site ↗
UCLA Health
📍 Los Angeles, CA
🔬 UDNBaylor College of Medicine UDN Clinical Site ↗
Baylor College of Medicine
📍 Houston, TX
🔬 UDNHarvard/MGH UDN Clinical Site ↗
Massachusetts General Hospital
📍 Boston, MA
🏥 NORDMayo Clinic Center for Individualized Medicine ↗
Mayo Clinic
📍 Rochester, MN
👤 Mayo Clinic Center for Individualized Medicine
🏥 NORDUCLA Rare Disease Day Program ↗
UCLA Health
📍 Los Angeles, CA
Travel Grants
No travel grants are currently matched to Genetic tumor of hematopoietic and lymphoid tissues.
Community
No community posts yet. Be the first to share your experience with Genetic tumor of hematopoietic and lymphoid tissues.
Start the conversation →Latest news about Genetic tumor of hematopoietic and lymphoid tissues
No recent news articles for Genetic tumor of hematopoietic and lymphoid tissues.
Follow this condition to be notified when news becomes available.
Caregiver Resources
NORD Caregiver Resources
Support, advocacy, and financial assistance for caregivers of rare disease patients.
Mental Health Support
Rare disease caregiving can be isolating. Connect with counseling and peer support.
Family & Caregiver Grants
Financial assistance programs specifically for caregivers of rare disease patients.
Social Security Disability
Learn how rare disease patients may qualify for SSDI/SSI benefits.
Questions for your doctor
Bring these to your next appointment
- Q1.What specific genetic change is causing my condition, and what does it mean for my treatment?,Should my family members be tested for the same genetic change?,What are my treatment options, and which do you recommend for my specific subtype?,Am I a candidate for stem cell transplantation?,What surveillance or monitoring plan should I follow going forward?,Are there any clinical trials available for my specific genetic subtype?,What signs or symptoms should prompt me to seek emergency care?
Common questions about Genetic tumor of hematopoietic and lymphoid tissues
What is Genetic tumor of hematopoietic and lymphoid tissues?
Genetic tumor of hematopoietic and lymphoid tissues is a broad category of rare cancers that arise in the blood-forming (hematopoietic) and immune system (lymphoid) cells due to inherited genetic changes. Unlike most blood cancers that develop from random mutations over a lifetime, these tumors have a genetic basis, meaning a person is born with or inherits gene changes that significantly increase their risk of developing these cancers. The blood and immune system are affected, which can lead to problems with normal blood cell production, immune function, and the growth of abnormal cells in th
Which specialists treat Genetic tumor of hematopoietic and lymphoid tissues?
3 specialists and care centers treating Genetic tumor of hematopoietic and lymphoid tissues are listed on UniteRare, sourced from ClinicalTrials.gov principal investigators, published research, and the NPPES NPI registry.