Gastrointestinal stromal tumorNews & Research
15 curated articles for Gastrointestinal stromal tumor — FDA updates, peer-reviewed research, clinical-trial milestones, and sponsor press releases. Sorted newest-first.
- Endoscopy May 8, 2026
Endoscopic submucosal tunneling resection via a transantral approach for duodenal bulb gastrointestinal stromal tumor.
Endoscopic submucosal tunneling resection via a transantral approach for duodenal bulb gastrointestinal stromal tumor.
Why it matters: Recent peer-reviewed research on Gastrointestinal stromal tumor that may be relevant for patients and caregivers.
- Gan to kagaku ryoho. Cancer & chemotherapy May 7, 2026
[A Case of Epithelioid-Type Small Intestinal Gastrointestinal Stromal Tumor with Positive PDGFRA Discovered Because of Small Intestinal Intussusception].
Adult intussusception is a rare condition, accounting for approximately 5% of all intussusception cases, and is often caused by organic lesions, such as tumors. We report a rare case of a small intestinal gastrointestinal stromal tumor(GIST)presenting with intussusception. The patient was an older a...
Why it matters: Recent peer-reviewed research on Gastrointestinal stromal tumor that may be relevant for patients and caregivers.
- Digestive diseases (Basel, Switzerland) May 7, 2026
Prediction Model of Malignant Risk of Gastrointestinal Stromal Tumor Based on Endoscopic Ultrasonography.
Gastrointestinal stromal tumors (GISTs) are clinically heterogeneous mesenchymal tumors, and accurate assessment of their malignancy is crucial for determining treatment strategies and predicting patient prognosis. This study aims to establish and validate a preoperative prediction model for the mal...
Why it matters: Recent peer-reviewed research on Gastrointestinal stromal tumor that may be relevant for patients and caregivers.
- Annals of medicine and surgery (2012) May 4, 2026
Small bowel volvulus revealing advanced jejunal gastrointestinal stromal tumor with diffuse metastases: a case report.
Gastrointestinal stromal tumors (GISTs) are the most common mesenchymal tumors of the gastrointestinal tract, with 25-30% arising from the small intestine. While GISTs commonly present with abdominal pain or gastrointestinal bleeding, they may rarely manifest as acute surgical emergencies such as sm...
Why it matters: Recent peer-reviewed research on Gastrointestinal stromal tumor that may be relevant for patients and caregivers.
- Digestive diseases and sciences May 3, 2026
Rectal Gastrointestinal Stromal Tumor Resected by Endoscopic Submucosal Dissection.
Rectal Gastrointestinal Stromal Tumor Resected by Endoscopic Submucosal Dissection.
Why it matters: Recent peer-reviewed research on Gastrointestinal stromal tumor that may be relevant for patients and caregivers.
- Current treatment options in oncology Apr 24, 2026
Imaging Strategies and Research Advances in Gastrointestinal Stromal Tumors.
Imaging Strategies and Research Advances in Gastrointestinal Stromal Tumors.
Why it matters: Recent peer-reviewed research on Gastrointestinal stromal tumor that may be relevant for patients and caregivers.
- Journal of medicinal chemistry Apr 23, 2026
Design and Synthesis of BLU-654, a Potent and Selective Mutant KIT V654A Inhibitor for the Treatment of Imatinib-Resistant GIST.
Gastrointestinal stromal tumor (GIST) is the most common type of sarcoma of the gastrointestinal tract, with approximately 5000 new cases annually in the USA. Approximately 80% of GIST cases are driven by activating mutations in KIT in exon 9 or 11. Resistance to present therapies like imatinib ofte...
Why it matters: Recent peer-reviewed research on Gastrointestinal stromal tumor that may be relevant for patients and caregivers.
- Annals of surgical oncology Apr 13, 2026
Optimizing Surgical Strategies and Prognostic Outcomes in Duodenal Gastrointestinal Stromal Tumors.
Duodenal gastrointestinal stromal tumors (GISTs) are rare, and evidence regarding optimal surgical strategy, perioperative imatinib use, and long-term outcomes remains limited. This study evaluated clinicopathologic characteristics, prognostic factors, and survival outcomes in a large single-center ...
Why it matters: Recent peer-reviewed research on Gastrointestinal stromal tumor that may be relevant for patients and caregivers.
- Drug design, development and therapy Apr 6, 2026
Targeted Therapy for Advanced Gastrointestinal Stromal Tumors: Evolution and Future Directions.
Gastrointestinal stromal tumor (GIST) is the most common mesenchymal tumor of the gastrointestinal tract, with its pathogenesis primarily linked to activating mutations in the KIT or platelet derived growth factor receptor alpha ( PDGFRA ) genes. Surgical resection remains the standard curative trea...
Why it matters: Recent peer-reviewed research on Gastrointestinal stromal tumor that may be relevant for patients and caregivers.
- Anticancer research Mar 27, 2026
Feasibility of Elastography for Preoperative Prediction of Malignancy of Gastrointestinal Stromal Tumor of the Stomach.
There are several well-known classifications for determining the grade of malignancy of gastrointestinal stromal tumor (GIST), but these classifications depend exclusively on invasive methods, including biopsy. Therefore, a minimally invasive examination modality is needed to preoperatively predict ...
Why it matters: Recent peer-reviewed research on Gastrointestinal stromal tumor that may be relevant for patients and caregivers.
- Cureus Mar 13, 2026
Large Pancreatic Gastrointestinal Stromal Tumor: A Diagnostic Quandary.
Gastrointestinal stromal tumors (GISTs) are rare mesenchymal neoplasms typically arising from the gastrointestinal tract, most often in the stomach or small intestine. Primary pancreatic GIST is exceedingly rare, with fewer than 50 cases reported in the literature. We present a unique case of a 77-y...
Why it matters: Recent peer-reviewed research on Gastrointestinal stromal tumor that may be relevant for patients and caregivers.
- BioMed research international Mar 11, 2026
Beyond Laparotomy: Multimodal Strategies and Emerging Evidence in Minimally Invasive Management of Gastric Gastrointestinal Stromal Tumors.
Gastrointestinal stromal tumor (GIST) is a type of potentially malignant mesenchymal tumor, thought to arise from the interstitial cells of the gut. More than half of all GIST cases occur primarily in the stomach. Currently, radical resection remains the only curative treatment for this disease. Thi...
Why it matters: Recent peer-reviewed research on Gastrointestinal stromal tumor that may be relevant for patients and caregivers.
- Surgical oncology Mar 8, 2026
Surgical management of gastrointestinal stromal tumor (GIST)-Induced sarcomatosis (GISTOSIS).
The optimal management of intra-abdominal dissemination of gastrointestinal stromal tumor (GISTosis) remains unclear. We performed a multi-institutional retrospective review of patients undergoing cytoreductive surgery (CRS) to evaluate overall (OS) and recurrence-free survival (RFS), and the impact...
Why it matters: Recent peer-reviewed research on Gastrointestinal stromal tumor that may be relevant for patients and caregivers.
- Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract Feb 19, 2026
The efficacy of immunotherapy in the treatment of tyrosine kinase inhibitor-refractory gastrointestinal stromal tumors: a systematic review and meta-analysis.
Gastrointestinal stromal tumors (GISTs) are the most common mesenchymal neoplasms of the gastrointestinal tract. The advent of tyrosine kinase inhibitors (TKIs), such as imatinib, has significantly improved clinical outcomes in patients with GISTs by delaying metastasis and prolonging survival. Howe...
Why it matters: Recent peer-reviewed research on Gastrointestinal stromal tumor that may be relevant for patients and caregivers.
- Journal of surgical case reports Feb 16, 2026
Incidental finding of gastrointestinal stromal tumor in appendix.
In the present case report, we have described the incidental finding of a gastrointestinal stromal tumor (GIST) in the appendix following surgical evaluation of a possible closed loop small bowel obstruction in the right lower quadrant. Upon exploration inside the abdomen, the distal ileum and proxi...
Why it matters: Recent peer-reviewed research on Gastrointestinal stromal tumor that may be relevant for patients and caregivers.
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Articles aggregated from peer-reviewed journals (PubMed), sponsor press releases, SEC 8-K filings, and FDA announcements. Original-source links are preserved on each article page. Editorial tags (Breaking / Notable / Update) reflect UniteRare's curation-time priority assessment.