Facial dermoid cyst

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2Specialists8Treatment centers

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Overview

A facial dermoid cyst is a benign congenital developmental cyst that occurs on the face, most commonly near the eyebrows (particularly at the lateral brow near the frontzygomatic suture), the nasal bridge, or along embryonic fusion lines. These cysts arise from ectodermal tissue that becomes trapped beneath the skin surface during embryonic development when facial processes fuse together. They are lined by keratinized stratified squamous epithelium and may contain skin appendages such as hair follicles, sebaceous glands, and sweat glands, along with keratin, hair, and sometimes fatty material. Facial dermoid cysts typically present at birth or during early childhood as a firm, non-tender, subcutaneous nodule that is usually painless and slow-growing. The most common location is the lateral eyebrow region, but they can also occur at the nasal root, midline of the nose, or other facial sites along embryonic fusion lines. While most are superficial, some dermoid cysts — particularly those located at the nasal bridge or midline — may extend deeper through bone and potentially communicate with intracranial structures, which necessitates imaging (CT or MRI) prior to surgical intervention to evaluate the full extent of the lesion. The primary treatment for facial dermoid cysts is complete surgical excision, which is both diagnostic and curative. Surgery is generally recommended to prevent complications such as infection, rupture (which can cause an inflammatory reaction), or progressive enlargement that may lead to cosmetic deformity or pressure effects on surrounding structures including the orbit. Incomplete excision may result in recurrence. The prognosis following complete surgical removal is excellent, with low recurrence rates. Facial dermoid cysts are not associated with malignant transformation.

Also known as:

Inheritance

Sporadic

Usually appears on its own, not inherited from a parent

Age of Onset

Neonatal

Begins at or shortly after birth (first 4 weeks)

Orphanet ↗NORD ↗

Treatments

No FDA-approved treatments are currently listed for Facial dermoid cyst.

View clinical trials →

No actively recruiting trials found for Facial dermoid cyst at this time.

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Specialists

2 foundView all specialists →
MP
Matthew L Speltz, PhD
SEATTLE, WA
Specialist
PI on 1 active trial
CM
Carrie L Heike, MD, MS
SEATTLE, WA
Specialist
PI on 1 active trial

Treatment Centers

8 centers
🏥 NORD

Baylor College of Medicine Rare Disease Center

Baylor College of Medicine

📍 Houston, TX

🏥 NORD

Stanford Medicine Rare Disease Center

Stanford Medicine

📍 Stanford, CA

🔬 UDN

NIH Clinical Center Undiagnosed Diseases Program

National Institutes of Health

📍 Bethesda, MD

🔬 UDN

UCLA UDN Clinical Site

UCLA Health

📍 Los Angeles, CA

🔬 UDN

Baylor College of Medicine UDN Clinical Site

Baylor College of Medicine

📍 Houston, TX

🔬 UDN

Harvard/MGH UDN Clinical Site

Massachusetts General Hospital

📍 Boston, MA

🏥 NORD

Mayo Clinic Center for Individualized Medicine

Mayo Clinic

📍 Rochester, MN

👤 Mayo Clinic Center for Individualized Medicine

🏥 NORD

UCLA Rare Disease Day Program

UCLA Health

📍 Los Angeles, CA

Travel Grants

No travel grants are currently matched to Facial dermoid cyst.

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Community

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Latest news about Facial dermoid cyst

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Caregiver Resources

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Financial assistance programs specifically for caregivers of rare disease patients.

Social Security Disability

Learn how rare disease patients may qualify for SSDI/SSI benefits.

Common questions about Facial dermoid cyst

What is Facial dermoid cyst?

A facial dermoid cyst is a benign congenital developmental cyst that occurs on the face, most commonly near the eyebrows (particularly at the lateral brow near the frontzygomatic suture), the nasal bridge, or along embryonic fusion lines. These cysts arise from ectodermal tissue that becomes trapped beneath the skin surface during embryonic development when facial processes fuse together. They are lined by keratinized stratified squamous epithelium and may contain skin appendages such as hair follicles, sebaceous glands, and sweat glands, along with keratin, hair, and sometimes fatty material.

How is Facial dermoid cyst inherited?

Facial dermoid cyst follows a sporadic inheritance pattern. Genetic counseling can help families understand recurrence risk and testing options.

At what age does Facial dermoid cyst typically begin?

Typical onset of Facial dermoid cyst is neonatal. Age of onset can vary across affected individuals.

Which specialists treat Facial dermoid cyst?

2 specialists and care centers treating Facial dermoid cyst are listed on UniteRare, sourced from ClinicalTrials.gov principal investigators, published research, and the NPPES NPI registry.