Clinical trials for Cystic fibrosis
100 recruiting or active trials synced from ClinicalTrials.gov.
ℹ
Clinical trial records are synced from ClinicalTrials.gov through automated extraction.
Report missing data- RECRUITINGPhase 1NCT07437105Dose Escalation Study Evaluating the Safety and Pharmacokinetics of VX-272 in Healthy ParticipantsVertex Pharmaceuticals Incorporated
- RECRUITINGN/ANCT07436351ACT With CF Self-Help ToolkitThomas Jefferson University
- RECRUITINGNCT07369414Environmental Reservoirs of Non-tuberculous Mycobacteria in Cystic Fibrosis Households: A Case-control Study of Exposure Risk at HomeResearch Center Borstel · PI: Alexander Mischnik, Prof. Dr. med.
- RECRUITINGN/ANCT07314229Prevalence of Exercise-induced Ventilatory Limitation and Associated Factors in Patients With Cystic Fibrosis Receiving Elexacaftor-Tezacaftor-IvacaftorUniversity Hospital, Lille
- RECRUITINGNCT07083557Routine Validation and Reproducibility Testing of Laboratory Assays and Research Techniques Used for Endocrine, Cardiometabolic, and Musculoskeletal Disorder Research (VALD)Bettina Mittendorfer · PI: Bettina Mittendorfer, PhD
- RECRUITINGNCT07505797ATUSA Ultrasound Diagnostic Imaging for Breast Lesions Evaluation (AUDIBLE)iSono Health, Inc.
- RECRUITINGPhase 1NCT07283770Dose Escalation Study Evaluating the Safety and Pharmacokinetics of VX-581 in Healthy ParticipantsVertex Pharmaceuticals Incorporated · PI: Medical Information
- RECRUITINGNCT07363304Impact of Elexacaftor-Tezacaftor-Ivacaftor Treatment on Metabolic, Epigenetic and Fecal Microbiota Profiles in People With Cystic Fibrosis.Meyer Children's Hospital IRCCS
- RECRUITINGN/ANCT07508904Exercises' Effect on Muscle Strength, Aerobic Capacity and Respiratory Functions in Cystic FibrosisRiphah International University · PI: Danish Hassan, PhD
- ACTIVE NOT RECRUITINGPhase 2NCT07108153Proof-of-concept Study to Evaluate the Safety, Tolerability, Pharmacodynamics, and Pharmacokinetics of SION-719 When Added to TrikaftaSionna Therapeutics Inc. · PI: Medical Director
- RECRUITINGNCT07245407A Translational Study for Phenotyping and Endotyping Chinese Patients With NCFBEAstraZeneca · PI: Jinfu Xu, Doctor
- RECRUITINGNCT07342920Study of the Prevalence of Active/Passive Smoking and Vaping Among Patients With Cystic FibrosisUniversity Hospital, Strasbourg, France
- RECRUITINGN/ANCT07484607Understanding Inflammation, InFection and Interventions in Severe Exacerbations of Cystic FibrosisAlexander Horsley · PI: Alexander Horsley, MA MBChB MRCP PhD FERS
- RECRUITINGN/ANCT07289100Novel Sensors and Artificial Intelligence for Detection of Acute Pulmonary Exacerbations in Cystic Fibrosis and BronchiectasisPapworth Hospital NHS Foundation Trust · PI: Andres Floto
- RECRUITINGNCT06837181Studying the Presence of CFRD Complications With Thoughtful Recruitment (SPeCTRuM)Jaeb Center for Health Research
- RECRUITINGNCT06984679Physical Impairments in Children With Cystic FibrosisIzmir Democracy University · PI: Gülşah Barğı, Assoc Prof
- RECRUITINGPhase 1NCT07035990Safety, Tolerability, and Pharmacokinetics of Multiple Dose Combinations of SION-451 and Complementary Modulators SION-2222 and SION-109 in Healthy Participants.Sionna Therapeutics Inc. · PI: Philip Ryan, MBBS, BMedSc, PhD, DPM, FFPM
- RECRUITINGPhase 3NCT06996951Sinonasal Therapies and Histologic Correlations of Patients With Cystic Fibrosis in the Era of Highly Effective Modulator TherapyIndiana University · PI: Elisa Illing, MD
- RECRUITINGNCT0606672319F MRI in Healthy Children and Children With Mild Cystic Fibrosis Lung DiseaseUniversity of North Carolina, Chapel Hill · PI: Jennifer L Goralski, MD
- RECRUITINGN/ANCT06642610CGM Dynamic Index for Predicting Prediabetes in Cystic FibrosisIndiana University · PI: Eslam Montaser, PhD
- RECRUITINGNCT06797206A Study of Females With CF Throughout Pregnancy and Post-partum, and Follow up of Their OffspringRoyal Brompton & Harefield NHS Foundation Trust · PI: Imogen Felton
- RECRUITINGN/ANCT07304362The School-Age Children With Cystic Fibrosis and Their Parents on Health LiteracyUniversity of Yalova · PI: DUYGU DEMİR Associate Professor
- RECRUITINGPhase 4NCT07148739Ensuring Access to Optimal Therapy in CF: The ENACT StudyArkansas Children's Hospital Research Institute · PI: Jennifer S Guimbellot, Medical Degree and License
- RECRUITINGNCT07048574TIDES 2.0: Prevalence and Longitudinal Course of Depression, Anxiety, and Behavior Problems in Children With Cystic Fibrosis Under 12 Years of AgeState University of New York at Buffalo
- RECRUITINGPhase 3NCT06810167Assessing Tenapanor as a Treatment of CF-related Constipation.Massachusetts General Hospital · PI: Christoher D Velez, MD
- ACTIVE NOT RECRUITINGPHASE1, PHASE2NCT06962852A Long-term Study to Monitor the Health Status of People With Cystic Fibrosis Who Took Part in a Previous Study With BI 3720931 (Lenticlair™-ON)Boehringer Ingelheim
- RECRUITINGNCT06940531Identifying the Causes and Risk Factors of Pulmonary Exacerbations in Cystic FibrosisAlexander Horsley
- ACTIVE NOT RECRUITINGNCT07022327Ivacaftor Impact in an Adolescent Without a Cystic Fibrosis-Associated CFTR (Cystic Fibrosis Transmembrane Conductance Regulator) Mutation for Chronic Pancreatitis: Single-Patient Study Tracking Flare Frequency and Health Data Compared to Historical Records.Mission: Cure · PI: Nicholas Schork, PhD
- ENROLLING BY INVITATIONN/ANCT07417267Clean Air for Rare MUcociliary Clearance dIsordersUniversity of Cyprus
- RECRUITINGNCT06356246Oral Health Status of Cystic Fibrosis Patients. An Online Survey in Collaboration With the Vaincre la Mucoviscidose Patient Association.Assistance Publique - Hôpitaux de Paris
- RECRUITINGN/ANCT06616857Personalized Mobile Health Platform to Promote Physical Activity in Adolescents and Young Adults With Cystic FibrosisNemours Children's Clinic
- RECRUITINGN/ANCT06487273Long-term Evaluation of the SIMEOX Device at Home in Non-cystic Fibrosis BronchiectasisPhysio-Assist · PI: Sylvie Leroy, MD
- RECRUITINGPhase 2NCT06775340Study of RSS0343 Tablets in Patients With Non-cystic Fibrosis BronchiectasisJiangsu HengRui Medicine Co., Ltd.
- RECRUITINGN/ANCT06560463Continuous Glucose Monitoring and OGTT Screen for Cystic Fibrosis Related Diabetes in Cystic FibrosisMedical College of Wisconsin · PI: julie A. Biller, MD
- RECRUITINGNCT06595420Kidney Function in People With Cystic Fibrosis in the Era of HEMTUniversity of Virginia
- RECRUITINGN/ANCT06836453Evaluation of New Device for Beta-adrenergic Sweat Test in the Context of Stratification of Patient With Cystic FibrosisCliniques universitaires Saint-Luc- Université Catholique de Louvain · PI: Sophie Gohy
- RECRUITINGPhase 2NCT06747858Safety, Tolerability and Efficacy Study of ARCT-032 in People With Cystic FibrosisArcturus Therapeutics, Inc.
- RECRUITINGN/ANCT06654752Streamlined Treatment of Pulmonary Exacerbations in PediatricsUniversity of Washington, the Collaborative Health Studies Coordinating Center · PI: D. B. Sanders, MD, MS
- RECRUITINGN/ANCT06457451Impact of a Coordinated Dietetic-adapted Physical Activity Program on the Percentage of Lean Body Mass in Adults With Cystic Fibrosis Treated With Elexacaftor-Tezacaftor-Ivacaftor: Multicentre Randomised Controlled TrialUniversity Hospital, Tours · PI: Julie MANKIKIAN, MD
- ACTIVE NOT RECRUITINGPhase 3NCT06460506Evaluation of Long-term Safety and Efficacy of ELX/TEZ/IVA in Cystic Fibrosis Participants 12 Months of Age and OlderVertex Pharmaceuticals Incorporated
- RECRUITINGN/ANCT06617013GERD in Children With Cystic FibrosisDuke University · PI: Shatha Yousef
- RECRUITINGPhase 4NCT06242795Hypertonic Saline in NCFBUniversity of North Carolina, Chapel Hill · PI: Katherine A. Despotes, MD
- RECRUITINGNCT06915961Epididymis Protein 4 and Pulmonary Function With Quality Improvement Protocol Among Cystic Fibrosis PatientsAin Shams University · PI: Eman Fawzy
- RECRUITINGN/ANCT06313827e-Health Program to Prevent Exacerbations in the Cystic Fibrosis PopulationUniversity of Valencia
- RECRUITINGPhase 3NCT06660992A Study to Assess the Efficacy and Safety of HSK31858 in Participants With Non-Cystic Fibrosis BronchiectasisHaisco Pharmaceutical Group Co., Ltd.
- RECRUITINGPhase 3NCT06449677Bionic Pancreas in CFRDJaeb Center for Health Research · PI: Melissa Putman, MD
- RECRUITINGN/ANCT06504589A Research Study to Advance the CF Therapeutics Pipeline for People Without ModulatorsNicole Hamblett · PI: Deepika Polineni, MD, MPH
- RECRUITINGNCT06602869Cellular Markers in Treated or Untreated Non-tuberculous Mycobacterial Respiratory Infection in Patients With Cystic FibrosisUniversity Hospital, Montpellier · PI: Raphael CHIRON, MD
- RECRUITINGPhase 1NCT06526923A Phase 1/2 Trial of SP-101 for the Treatment of Cystic Fibrosis (CF)Spirovant Sciences, Inc. · PI: Jessica Lee, MPH
- RECRUITINGN/ANCT05998629Skin-interfaced Colorimetric Bifluidic Sweat Sensor Device for the Diagnosis of Cystic Fibrosis (CF)Milton S. Hershey Medical Center · PI: Robert Vender
- RECRUITINGPHASE2, PHASE3NCT06413368Maralixibat in Patients With Cystic Fibrosis and Constipation, A Within-Subjects Pilot StudyChildren's Hospital Los Angeles · PI: Jaya Punati, MD
- RECRUITINGPhase 2NCT06429176Safety, Tolerability, Pharmacokinetics, and Preliminary Efficacy of SPL84 in Patients with Cystic FibrosisSpliSense Ltd.
- RECRUITINGN/ANCT06370962Circadian Rhythm Disorders in Children With Cystic Fibrosis Under CFTR (Cystic Fibrosis Transmembrane Conductance Regulator) ModulatorsHospices Civils de Lyon · PI: Laurianne COUTIER, MD
- ACTIVE NOT RECRUITINGN/ANCT06120465YOGA-CF (Yoga Outcomes Get Assessed in Cystic Fibrosis)Royal Brompton & Harefield NHS Foundation Trust · PI: Nicholas Simmonds
- RECRUITINGPHASE1, PHASE2NCT06016088A Double-Blind, Active-Controlled, Multiple-Ascending Dose Study of Aerosolized RSP-1502 in Subjects With CF and Chronic PA Lung InfectionRespirion Pharmaceuticals Pty Ltd
- RECRUITINGNCT06216704Skeletal Health and Bone Marrow Composition in Adolescents With Cystic FibrosisMassachusetts General Hospital · PI: Rebecca Gordon, MD
- RECRUITINGNCT06302270CFTR Modulators in Pregnancy and PostpartumRegion Stockholm
- ACTIVE NOT RECRUITINGN/ANCT06322446Exercise in People With Cystic Fibrosis on CFTR Modulator TherapyUniversidad Politecnica de Madrid · PI: Margarita Perez Ruiz, PhD
- RECRUITINGN/ANCT07192679MAGNIFY - Pulmonary Magnetic Resonance Imaging for Cystic FibrosisSheffield Teaching Hospitals NHS Foundation Trust · PI: Jim Wild, Professor
- ENROLLING BY INVITATIONNCT06262282Mycobacteriophage Treatment of Non-tuberculosis MycobacteriaNational Jewish Health · PI: Jerry Nick, MD
- RECRUITINGPhase 2NCT06237335A Phase 2 Study Evaluating Safety and Tolerability of RCT2100 (CFTR mRNA) in Healthy Participants and in Participants With CFReCode Therapeutics · PI: John Matthews, MBBS, MCRP, PhD
- ACTIVE NOT RECRUITINGPHASE2, PHASE3NCT06149793SGLT2 Inhibitor Therapy in Cystic Fibrosis-related DiabetesUniversity of Minnesota
- RECRUITINGEarly Phase 1NCT06339593Regional Monitoring of CF Lung DiseaseChildren's Hospital Medical Center, Cincinnati · PI: Jason C Woods, PhD
- RECRUITINGN/ANCT06284577Quality of Life and Gut Health in Pediatric Patients With Cystic FibrosisOslo University Hospital
- RECRUITINGNCT05982795Impact of Highly Effective Modulator Therapy on the Cystic Fibrosis MicrobiomeDartmouth-Hitchcock Medical Center · PI: Ryan E Little, MD
- ACTIVE NOT RECRUITINGN/ANCT06030206Lung Transplant READY CF 2: A Multi-site RCTUniversity of Washington · PI: Kathleen Ramos, MD, MSc
- RECRUITINGNCT06599892CF Organization of Care in the Era of Highly Effective Modulator.Hospices Civils de Lyon · PI: Philippe REIX, Professor
- RECRUITINGN/ANCT05723445The Effects of a Low Glycemic Load Diet on Dysglycemia and Body Composition in Adults With Cystic Fibrosis-Related DiabetesRhode Island Hospital · PI: Kevin J Scully, MB BCh BAO
- ENROLLING BY INVITATIONPhase 3NCT05844449Evaluation of Long-Term Safety and Efficacy of Vanzacaftor/Tezacaftor/Deutivacaftor in Cystic Fibrosis Participants 1 Year of Age and OlderVertex Pharmaceuticals Incorporated
- RECRUITINGN/ANCT05766774FEED-Cystic Fibrosis (FEED-CF)Emory University · PI: Jessica A Alvarez, PhD, RD
- RECRUITINGN/ANCT05818319Cystic Fibrosis in the Kidney: Monitoring the Effectiveness of Elexacaftor/tezacaftor/ivacaftor in Urine After a Short Pause of TherapyUniversity of Aarhus · PI: Jens G. Leipziger
- ACTIVE NOT RECRUITINGN/ANCT05562492Closed-loop for People Living With Cystic Fibrosis Related DiabetesUniversity of Cambridge
- RECRUITINGEarly Phase 1NCT06163482Hormonal Responses to a Mixed Meal in People With Cystic FibrosisUniversity of Cincinnati · PI: Jason Winnick, PhD
- RECRUITINGPhase 1NCT05802264Study to Assess Amphotericin B Cystetic for Inhalation (ABCI) Doses in Healthy Volunteers & People with Cystic FibrosisCystetic Medicines, Inc. · PI: Martin Burke, MD, PhD
- RECRUITINGPHASE1, PHASE2NCT05668741A Phase 1/2 Study of VX-522 in Participants With Cystic Fibrosis (CF)Vertex Pharmaceuticals Incorporated
- ACTIVE NOT RECRUITINGN/ANCT06084468Cardiac Structure and Function in Patients with Cystic FibrosisHerlev and Gentofte Hospital · PI: Tor Biering-Sørensen, Professor MD PhD MPH
- ACTIVE NOT RECRUITINGPhase 3NCT05331183Study to Evaluate Elexacaftor/Tezacaftor/Ivacaftor (ELX/TEZ/IVA) Long-term Safety and Efficacy in Subjects Without F508delVertex Pharmaceuticals Incorporated
- ACTIVE NOT RECRUITINGN/ANCT05206097Determinants of Daily Physical Activity Level in Patients With Cystic Fibrosis - Pilot Study ProtocolUniversity Hospital, Limoges
- ACTIVE NOT RECRUITINGN/ANCT05362344Colorectal Cancer Screening in Cystic FibrosisUniversity of Washington, the Collaborative Health Studies Coordinating Center · PI: Christine Hachem, MD
- RECRUITINGN/ANCT05463289ACCESS 2: AI for pediatriC diabetiC Eye examS Study 2Johns Hopkins University · PI: Risa M Wolf, MD
- RECRUITINGPhase 3NCT05422222Evaluation of VX-121/Tezacaftor/Deutivacaftor in Cystic Fibrosis (CF) Participants 1 Through 11 Years of AgeVertex Pharmaceuticals Incorporated · PI: Medical Information
- RECRUITINGPhase 4NCT05517655BEGIN Novel ImagiNG BiomarkersChildren's Hospital Medical Center, Cincinnati · PI: Jason Woods, PhD
- RECRUITINGPhase 2NCT052482304D-710 in Adult Patients With Cystic Fibrosis4D Molecular Therapeutics · PI: Sam Moskowitz MD
- RECRUITINGN/ANCT04137133Patienthèque of Finisterian (South of Brittany) Children With Cystic Fibrosis in the Time of Precision MedicineUniversity Hospital, Brest
- ACTIVE NOT RECRUITINGEarly Phase 1NCT03435939Effect of Losartan in Cystic Fibrosis (CF)-NIH Grant #133240University of Kansas Medical Center · PI: Matthias Salathe, MD
- ACTIVE NOT RECRUITINGNCT05074680COVID-19 Antibody Responses In Cystic FibrosisInsel Gruppe AG, University Hospital Bern · PI: Reta Fischer Biner, MD
- ACTIVE NOT RECRUITINGN/ANCT06964074PEP and O-PEP Device for Nebulization in Cystic FibrosisNational Institute for Tuberculosis and Lung Diseases, Poland · PI: Katarzyna Warzeszak
- ACTIVE NOT RECRUITINGN/ANCT06057558Airway Microbiome of Cystic Fibrosis PatientsUniversity Hospital, Antwerp · PI: Kim Van Hoorenbeeck
- RECRUITINGNCT05099939Identification of Dysglycemia With Continuous Glucose Monitoring to Assess Clinical Evolution in Cystic FibrosisInstitut de Recherches Cliniques de Montreal · PI: Rémi Rabasa-Lhoret
- RECRUITINGNCT05279040Trikafta Exercise Study in Cystic FibrosisUniversity of British Columbia · PI: Jordan A Guenette, PhD
- RECRUITINGN/ANCT05200429Canadian Observational Study Evaluating the Long-term IMPACT of Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) Modulators on People With CFUniversity of British Columbia · PI: Jonathan Rayment, MDCM
- ACTIVE NOT RECRUITINGNCT05052294COVID-19 Antibody Responses in Cystic FibrosisUniversity Hospital, Motol · PI: Pavel Drevinek, MD
- RECRUITINGPhase 4NCT03921060Markers of Osteoporosis in Cystic FibrosisUniversity of Texas Southwestern Medical Center
- RECRUITINGPhase 2NCT04731272GLP-1 Agonist Therapy in Cystic Fibrosis-Related Glucose IntoleranceUniversity of Pennsylvania · PI: Michael R Rickels, MD, MS
- RECRUITINGN/ANCT04580368Testing Drug Efficacy in Cystic Fibrosis Through N-of-1 TrialsChildren's Hospital Medical Center, Cincinnati · PI: John Brewington, MD
- RECRUITINGNCT06413459Identification of New Biological Markers for the Progression of Mycobacterium Abscessus-induced Lung Disease in Cystic FibrosisOspedale San Raffaele
- RECRUITINGN/ANCT04793867Regional Phenotyping of CF and Non-CF BronchiectasisChildren's Hospital Medical Center, Cincinnati · PI: Zackary I Cleveland, PhD
- RECRUITINGNCT06057714Quantitation and Spatial Registration of Airways Dysfunction With Dynamic 19F MRI in Cystic FibrosisUniversity of North Carolina, Chapel Hill · PI: Jennifer L Goralski, MD
- ENROLLING BY INVITATIONNCT04579211Prospective Analysis of Urine LAM to Eliminate NTM Sputum ScreeningJerry A. Nick, M.D. · PI: Jerry A. Nick, MD
- RECRUITINGNCT05017766NCCR AntiResist:: New Approaches to Combat Antibiotic-resistant BacteriaUniversity Hospital, Basel, Switzerland · PI: Nina Khanna, Prof.