Arterial duct anomaly

Last reviewed

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ORPHA:95485
Who is this for?
Show terms as
1FDA treatments9Active trials55Specialists8Treatment centers1Financial resources

Where are you in your journey?

UniteRare data is sourced from FDA.gov, ClinicalTrials.gov, Orphanet, OMIM, and NORD.
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Overview

Also known as:

Orphanet ↗NORD ↗

FDA & Trial Timeline

10 events
Dec 2025Starlight Cardiovascular Lifeline Ductus Arteriosus Stent IDE Study

Starlight Cardiovascular Inc — NA

TrialRECRUITING
May 2025Prophylactic IV Paracetamol in Extremely Premature Infants

Al-Quds University — PHASE2, PHASE3

TrialENROLLING BY INVITATION
Apr 2025Dynamic Changes of Ductus Arteriosus in < 31 Weeks Preterm Infants: an Observational Study

Daping Hospital and the Research Institute of Surgery of the Third Military Medical University

TrialACTIVE NOT RECRUITING
Mar 2025PREEMIE: Study for Treatment of PDA in Premature Infants

Merit Medical Systems, Inc. — NA

TrialRECRUITING
Feb 2025Early Hydrocortisone Versus Regular Treatment in Shock in Extremely Preterm Neonates - an Open Randomized Controlled Trial

Coordinación de Investigación en Salud, Mexico — PHASE4

TrialACTIVE NOT RECRUITING
Dec 2024PDA for Kidneys Study

University of Wisconsin, Madison

TrialRECRUITING
Oct 2024Outcome of Transcatheter Closure of Patent Ductus Arteriosus in Pediatric Cardiology Unit in 3 Years Duration

Assiut University — NA

TrialNOT YET RECRUITING
Oct 2024NeoDoppler: New Ultrasound Technology for Continuous Monitoring of Cerebral Circulation Pilot

St. Olavs Hospital

TrialRECRUITING
Sep 2024Study of Thoracic Ultrasound As a Response to the Closure of Hemodynamically Significant Patent Ductus Arteriosus in Premature Infants

Fondazione Policlinico Universitario Agostino Gemelli IRCCS

TrialRECRUITING
Jul 2024Precision Dosing of Oral Ibuprofen for PDA, A Pilot RCT

Hamilton Health Sciences Corporation — PHASE2

TrialRECRUITING

Data sourced from FDA regulatory filings and ClinicalTrials.gov. Updated periodically.

Treatments

1 available

NeoProfen

Ibuprofen lysine· Lundbeck, Inc.
NeoProfen is indicated to close a clinically significant patent ductus arteriosus (PDA) in premature infants weighing between 500 and 1500 g, who are no more than 32 weeks gestational age when usual m

NeoProfen is indicated to close a clinically significant patent ductus arteriosus (PDA) in premature infants weighing between 500 and 1500 g, who are no more than 32 weeks gestational age when usual medical management (e.g., fluid restriction, diuretics, respiratory support, etc.) is ineffective.

Clinical Trials

9 recruitingView all trials with filters →
Phase 31 trial
Management of the PDA Trial
Phase 3
Active
· Sites: Birmingham, Alabama; Palo Alto, California +17 more
Phase 21 trial
Precision Dosing of Oral Ibuprofen for PDA, A Pilot RCT
Phase 2
Actively Recruiting
PI: Samira Samiee-Zafarghandy, MD, FRCPC (McMaster University) · Sites: Hamilton, Ontario
N/A1 trial
Improving Care for Children With Congenital Heart Disease.
N/A
Enrolling by Invitation
PI: Henning Clausen, MD (Children's Heart Centre, University Hospital of Lu) · Sites: Lund, Skåne County · Age: 017 yrs
Other6 trials
Early Prediction of Spontaneous Patent Ductus Arteriosus (PDA) Closure and PDA-Associated Outcomes
Active
PI: Jonathan L Slaughter, MD, MPH (Nationwide Children's Hospital/The Ohio State Univ) · Sites: Columbus, Ohio; Columbus, Ohio +2 more
NeoDoppler: New Ultrasound Technology for Continuous Monitoring of Cerebral Circulation Pilot
Actively Recruiting
PI: Siri Ann Nyrnes, MD, PhD (Childrens Clinic, St. Olavs University Hospital an) · Sites: Trondheim
Post Marketing Clinical Follow Up Study to Evaluate Efficacy and Safety of the Occlutech PDA Occluder in Patients With Patent Ductus Arteriosus Defects
Actively Recruiting
· Sites: Montreal; Lille +13 more
Dynamic Changes of Ductus Arteriosus in < 31 Weeks Preterm Infants: an Observational Study
Active
· Sites: Chongqing, Chongqing Municipality
Amplatzer Piccolo Occluder Japan Post-marketing Database Surveillance
Active
· Sites: Tokyo
PDA for Kidneys Study
Actively Recruiting
PI: Matthew Harer, MD (University of Wisconsin, Madison) · Sites: Madison, Wisconsin

Specialists

Showing 25 of 55View all specialists →
JP
Jacob V Aranda, MD, PhD
DETROIT, MI
Specialist
PI on 2 active trials
WM
Wu Shiun Hsieh, M.D
Specialist
PI on 1 active trial
MM
Moshe Dotan, MD
Specialist
PI on 1 active trial
EM
Evan Zahn, MD
NEW HAVEN, CT
Specialist
PI on 1 active trial
MM
Mehmet Yekta Oncel, MD
PORT JEFFERSON, NY
Specialist
PI on 2 active trials
JM
J Lauren Ruoss, MD
GAINESVILLE, FL
Specialist
PI on 1 active trial
DP
Dmytro Dobryanskyy, MD, PhD
Specialist
PI on 1 active trial
WP
Willem P de Boode, MD PhD
Specialist
PI on 1 active trial
OE
Omer Ephrat
Specialist
PI on 1 active trial
CM
Curt DeGroff, MD
GAINESVILLE, FL
Specialist
PI on 1 active trial
MM
Matthew Harer, MD
MADISON, WI
Specialist
PI on 2 active trials
SM
Se In Sung, M.D.
Specialist
PI on 1 active trial
RM
Ronald Clyman, MD
SAN FRANCISCO, CA
Specialist
PI on 1 active trial
MM
Mariana Baserga, MD
SALT LAKE CITY, UT
Specialist
PI on 4 active trials
JM
Jeffrey Feinstein, MD, MPH
WESTMONT, IL
Specialist
PI on 1 active trial
AP
Amish Jain, MD PhD
STANFORD, CA
Specialist
PI on 1 active trial
CM
Christoph Czernik, MD
Specialist
PI on 2 active trials
TD
Timo Saarela, M.D., Ph. D.
Specialist
PI on 1 active trial1 Arterial duct anomaly publication
JZ
Jennifer Zeitlin
NEW YORK, NY
Specialist
PI on 1 active trial29 Arterial duct anomaly publications
GP
Guy KONGOLO, PhD
Specialist
PI on 1 active trial
AM
Augustina Jankauskiene, MD
Specialist
PI on 1 active trial1 Arterial duct anomaly publication
NG
Nilufer Guzoglu
Specialist
PI on 1 active trial3 Arterial duct anomaly publications
IS
Ilene RS Sosenko
MIAMI, FL
Specialist
PI on 1 active trial

Treatment Centers

8 centers
🏥 NORD

Baylor College of Medicine Rare Disease Center

Baylor College of Medicine

📍 Houston, TX

🏥 NORD

Stanford Medicine Rare Disease Center

Stanford Medicine

📍 Stanford, CA

🔬 UDN

NIH Clinical Center Undiagnosed Diseases Program

National Institutes of Health

📍 Bethesda, MD

🔬 UDN

UCLA UDN Clinical Site

UCLA Health

📍 Los Angeles, CA

🔬 UDN

Baylor College of Medicine UDN Clinical Site

Baylor College of Medicine

📍 Houston, TX

🔬 UDN

Harvard/MGH UDN Clinical Site

Massachusetts General Hospital

📍 Boston, MA

🏥 NORD

Mayo Clinic Center for Individualized Medicine

Mayo Clinic

📍 Rochester, MN

👤 Mayo Clinic Center for Individualized Medicine

🏥 NORD

UCLA Rare Disease Day Program

UCLA Health

📍 Los Angeles, CA

Financial Resources

1 resources
NeoProfen(Ibuprofen lysine)Lundbeck, Inc.

Travel Grants

No travel grants are currently matched to Arterial duct anomaly.

Search all travel grants →NORD Financial Assistance ↗

Community

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Latest news about Arterial duct anomaly

Disease timeline:

New recruiting trial: Percutaneous Intervention Versus Observational Trial of Arterial Ductus in Low Weight Infants

A new clinical trial is recruiting patients for Arterial duct anomaly

New recruiting trial: Post Marketing Clinical Follow Up Study to Evaluate Efficacy and Safety of the Occlutech PDA Occluder in Patients With Patent Ductus Arteriosus Defects

A new clinical trial is recruiting patients for Arterial duct anomaly

New recruiting trial: PREEMIE: Study for Treatment of PDA in Premature Infants

A new clinical trial is recruiting patients for Arterial duct anomaly

New recruiting trial: Postnatal Steroids Effects on Cardiac Function in Extremely Preterm

A new clinical trial is recruiting patients for Arterial duct anomaly

New recruiting trial: PDA for Kidneys Study

A new clinical trial is recruiting patients for Arterial duct anomaly

New recruiting trial: Long Term Follow-up of the TREOCAPA Study (TREOCAPA-LT)

A new clinical trial is recruiting patients for Arterial duct anomaly

New recruiting trial: Study of Thoracic Ultrasound As a Response to the Closure of Hemodynamically Significant Patent Ductus Arteriosus in Premature Infants

A new clinical trial is recruiting patients for Arterial duct anomaly

New recruiting trial: Starlight Cardiovascular Lifeline Ductus Arteriosus Stent IDE Study

A new clinical trial is recruiting patients for Arterial duct anomaly

New recruiting trial: Precision Dosing of Oral Ibuprofen for PDA, A Pilot RCT

A new clinical trial is recruiting patients for Arterial duct anomaly

New recruiting trial: NeoDoppler: New Ultrasound Technology for Continuous Monitoring of Cerebral Circulation Pilot

A new clinical trial is recruiting patients for Arterial duct anomaly

Caregiver Resources

NORD Caregiver Resources

Support, advocacy, and financial assistance for caregivers of rare disease patients.

Mental Health Support

Rare disease caregiving can be isolating. Connect with counseling and peer support.

Family & Caregiver Grants

Financial assistance programs specifically for caregivers of rare disease patients.

Social Security Disability

Learn how rare disease patients may qualify for SSDI/SSI benefits.

Common questions about Arterial duct anomaly

Are there clinical trials for Arterial duct anomaly?

Yes — 9 recruiting clinical trials are currently listed for Arterial duct anomaly on UniteRare. See the clinical trials section on this page for phase, sponsor, and site details sourced from ClinicalTrials.gov.

Which specialists treat Arterial duct anomaly?

25 specialists and care centers treating Arterial duct anomaly are listed on UniteRare, sourced from ClinicalTrials.gov principal investigators, published research, and the NPPES NPI registry.

What treatment and support options exist for Arterial duct anomaly?

1 patient support program are currently tracked on UniteRare for Arterial duct anomaly. See the treatments and support programs sections for copay assistance, eligibility, and contact details.