Pulmonary arterial hypertension

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At a Glance

Live from database

Regulatory Watchboard

10 events
Apr 2026

BOSENTAN: New indication approved

FDAcompleted
Apr 2026

BOSENTAN: New indication approved

FDAcompleted
Apr 2026TYVASO: New indication approved
FDAcompleted
Apr 2026

BOSENTAN: New indication approved

FDAcompleted
Mar 2026WINREVAIR: New indication approved
FDAcompleted
Mar 2026

BOSENTAN: New indication approved

FDAcompleted
Mar 2026

BOSENTAN: New indication approved

FDAcompleted
Mar 2026TRACLEER: New indication approved
FDAcompleted
Mar 2026TRACLEER: New indication approved
FDAcompleted
Mar 2026

BOSENTAN: New indication approved

FDAcompleted

Data from FDA regulatory filings and ClinicalTrials.gov. Updated periodically.

Financial Assistance

26 programs

FINANCIAL LANDSCAPE SUMMARY

26

Total programs

22

Open now

7

Foundation grants

13

Copay cards

6

Travel grants

Foundation Grants7

PAN Foundation — Pulmonary arterial hypertension

PAN Foundation

OpenContact for detailsApply ↗

NORD Patient Assistance — Pulmonary arterial hypertension

NORD Patient Assistance

OpenContact for detailsApply ↗

Good Days — Pulmonary arterial hypertension

Good Days

OpenContact for detailsApply ↗

HealthWell Foundation — Pulmonary arterial hypertension

HealthWell Foundation

OpenContact for detailsApply ↗

The Assistance Fund — Pulmonary arterial hypertension

The Assistance Fund

OpenContact for detailsApply ↗

Patient Advocate Foundation — Pulmonary arterial hypertension

Patient Advocate Foundation

OpenContact for detailsApply ↗

Patient Services Inc — Pulmonary arterial hypertension

Patient Services Inc

OpenContact for detailsApply ↗

Copay Assistance13

Treprostinil

United Therapeutics

OpenContact for detailsApply ↗

Ambrisentan

Gilead

OpenContact for detailsApply ↗

Ventavis

CoTherix, Inc.

OpenContact for details

TADALAFIL

Eli Lilly

OpenContact for detailsApply ↗

Sterile Diluent For Treprostinil

Dr.Reddy's Laboratories Inc.,

OpenContact for details

Uptravi

Janssen

OpenContact for details

Epoprostenol

GlaxoSmithKline

OpenContact for detailsApply ↗

SILDENAFIL CITRATE

Pfizer

OpenContact for detailsApply ↗

TYVASO

United Therapeutics

OpenContact for detailsApply ↗

Sildenafil

Pfizer

OpenContact for detailsApply ↗

Tyvaso DPI

United Therapeutics

OpenContact for detailsApply ↗

FLOLAN

GlaxoSmithKline

OpenContact for detailsApply ↗

OPSYNVI

Janssen

OpenContact for detailsApply ↗

Travel Grants6

GSK for You Patient Assistance Program

GSK

Contact for detailsApply ↗

ONWARD Patient Support Program

UCB

OpenContact for detailsApply ↗

Opsumit Patient Assistance Enrollment Form

Contact for detailsApply ↗

PAN Foundation Pulmonary Hypertension Copay Grant

PAN Foundation

ClosedUp to $14K/yrApply ↗

QuickRx Specialty Pharmacy Tyvaso Copay Assistance

QuickRx Specialty Pharmacy

OpenContact for detailsApply ↗

Tyvaso Patient Assistance Program

Contact for detailsApply ↗

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Approved Treatments

8 FDA-approved

Opsynvi

(MACITENTAN AND TADALAFIL)Orphan drug

Actelion Pharmaceuticals US, Inc.

Endothelin Receptor Antagonist [EPC]

12.1 Mechanism of Action Macitentan Endothelin (ET)-1 and its receptors (ETA and ETB) mediate a variety of deleterious effects, such as vasoconstricti...

Approved Mar 2024FDA label ↗

Tyvaso DPI

(treprostinil inhalation powder)Orphan drug

United Therapeutics Corporation

Prostacycline Vasodilator [EPC]

12.1 Mechanism of Action Treprostinil is a prostacyclin analogue. The major pharmacologic actions of treprostinil are direct vasodilation of pulmonary...

Approved May 2022FDA label ↗

Uptravi

(selexipag)Orphan drug

Janssen

Prostacyclin Receptor Agonist [EPC]

12.1 Mechanism of Action Selexipag is a prostacyclin receptor (IP receptor) agonist that is structurally distinct from prostacyclin. Selexipag is hydr...

Approved Dec 2015FDA label ↗

Opsumit

(macitentan)Orphan drug

Janssen

Endothelin Receptor Antagonist [EPC]

12.1 Mechanism of Action Endothelin (ET)-1 and its receptors (ET A and ET B ) mediate a variety of deleterious effects, such as vasoconstriction, fibr...

Approved Oct 2013FDA label ↗

Tyvaso

(treprostinil)Orphan drug

United Therapeutics

Prostacycline Vasodilator [EPC]

12.1 Mechanism of Action Treprostinil is a prostacyclin analogue. The major pharmacologic actions of treprostinil are direct vasodilation of pulmonary...

Approved Jul 2009FDA label ↗

Tadalafil

(TADALAFIL)Orphan drug

Northwind Health Company, LLC

Phosphodiesterase 5 Inhibitor [EPC]

12.1 Mechanism of Action Tadalafil is an inhibitor of phosphodiesterase type 5 (PDE5), the enzyme responsible for the degradation of cyclic guanosine ...

Approved May 2009FDA label ↗

Ambrisentan

(AMBRISENTAN)Orphan drug

Cipla USA Inc.

Endothelin Receptor Antagonist [EPC]

12.1 Mechanism of Action Endothelin-1 (ET-1) is a potent autocrine and paracrine peptide. Two receptor subtypes, ET A and ET B , mediate the effects o...

Approved Jun 2007FDA label ↗

Ventavis

(Iloprost inhalation solution)Orphan drug

CoTherix, Inc.

Approved Dec 2004

View full treatment details on disease page →

Clinical Trial Landscape

1 active trial
1N/A
1Total recruiting
Search clinical trials for Pulmonary arterial hypertension

Recent News & Research

6 articles
The Journal of heart and lung transplantation : the official publication of the International Society for Heart TransplantationApr 22, 2026

First longitudinal spatial transcriptomics analysis in pulmonary arterial hypertension.

First longitudinal spatial transcriptomics analysis in pulmonary arterial hypertension.

Read ↗
Future cardiologyApr 20, 2026

Evaluating sotatercept in the treatment of pulmonary arterial hypertension.

Pulmonary arterial hypertension (PAH) is a progressive disease characterized by pulmonary vascular remodeling, right ventricular overload, and premature death. Despite advances achieved through endoth...

Read ↗
Respiratory researchApr 11, 2026

Update on pulmonary hypertension.

The hemodynamic definition of pulmonary hypertension including a mean pulmonary arterial pressure > 20 mmHg is evidence based, but the threshold of 15 mmHg for the pulmonary...

Read ↗
Journal of hypertensionMar 25, 2026

Targeting the Hippo pathway in pulmonary arterial hypertension: emerging pharmacological strategies.

Pulmonary arterial hypertension (PAH) is a severe, progressive disease characterized by pulmonary vascular remodeling and increased resistance, ultimately leading to right heart failure and high morta...

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Journal of the American College of CardiologyMar 11, 2026

Pulmonary Hypertension Associated With Left Heart Disease: Challenges, Emerging Strategies, and Future Directions.

Pulmonary hypertension (PH) associated with left heart disease (LHD) is the most prevalent form of PH and is associated with substantial morbidity and mortality risk. Diagnosis is challenging because ...

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European heart journalMar 8, 2026

EP4/ANXA2 axis in pulmonary arterial hypertension: therapeutic implications.

Pulmonary arterial hypertension (PAH) is a progressive condition marked by the abnormal proliferation of pulmonary artery smooth muscle cells (PASMCs), leading to significant remodelling of the pulmon...

Read ↗

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Specialist Network

Top 6 by expertise

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