NON RARE IN EUROPE: Non-small cell lung cancer

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At a Glance

Live from database

Regulatory Watchboard

10 events
Mar 2026TILs Therapy for Multiple Primary Early-Stage NSCLC

Tianjin Medical University General Hospital — EARLY_PHASE1

TrialNOT YET RECRUITING
Mar 2026MEKINIST: New indication approved
FDAcompleted
Mar 2026MEKINIST: New indication approved
FDAcompleted
Mar 2026Anesthesia Comparison in Early-stage Small NSCLC: A Multicenter RCT

Tang-Du Hospital — NA

TrialNOT YET RECRUITING
Mar 2026Study on the Efficacy and Safety of JSKN016 as Neoadjuvant Therapy in Resectable Stage II-III Non-small Cell Lung Cancer Patients

Shanghai Pulmonary Hospital, Shanghai, China — PHASE2

TrialNOT YET RECRUITING
Feb 2026BRAFTOVI: New indication approved
FDAcompleted
Jan 2026Toripalimab Combined With Platinum-based Chemotherapy With or Without H1 Receptor Antagonist in the Perioperative Treatment of Resectable Non-small Cell Lung Cancer

Tianjin Medical University Cancer Institute and Hospital — PHASE2

TrialNOT YET RECRUITING
Jan 2026LORBRENA: New indication approved
FDAcompleted
Jan 2026Post-operative Radiotherapy After Neodjuvant Chemo-immunotherapy and Surgery in Stage III NSCLC

Centre hospitalier de l'Université de Montréal (CHUM) — PHASE2

TrialRECRUITING
Jan 2026Lidocaine Decreases Postoperative Lung Cancer Reoccurance and Metatasis Risk

First Affiliated Hospital of Ningbo University — NA

TrialNOT YET RECRUITING

Data from FDA regulatory filings and ClinicalTrials.gov. Updated periodically.

Financial Assistance

15 programs

FINANCIAL LANDSCAPE SUMMARY

15

Total programs

15

Open now

Patient Assistance Programs15

Alecensa

Hoffmann-La Roche, Inc. (c/o Genentech, Inc.)

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Ibtrozi

Nuvation Bio Inc.

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Alunbrig

Takeda Development Center Americas, Inc.

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ZYKADIA

Novartis Pharmaceuticals Corp.

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Avastin

Genentech, Inc.

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Iressa

AstraZeneca Pharmaceuticals LP

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Yervoy

Bristol-Myers Squibb Company

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Tagrisso

AstraZeneca Pharmaceuticals LP

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Lumakras

Amgen Inc.

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ROZLYTREK

Genentech, Inc.

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TAFINLAR

Novartis Pharmaceuticals Corp.

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VIZIMPRO

Pfizer, Inc.

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LORBRENA

Pfizer, Inc.

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GAVRETO�

Rigel Pharmaceuticals, Inc.

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Tepmetko

EMD Serono, Inc.

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Approved Treatments

8 FDA-approved

Ibtrozi

(taletrectinib)Orphan drug

Nuvation Bio Inc.

12.1 Mechanism of Action Taletrectinib is an inhibitor of tyrosine kinase ROS1, including ROS1 resistance mutations. Taletrectinib also showed inhibit...

Approved Jun 2025FDA label ↗

Augtyro

(repotrectinib)Orphan drug

Bristol Myers Squibb Company

Kinase Inhibitor [EPC]

12.1 Mechanism of Action Repotrectinib is an inhibitor of proto-oncogene tyrosine-protein kinase ROS1 (ROS1) and of the tropomyosin receptor tyrosine ...

Approved Nov 2023FDA label ↗

Braftovi

(encorafenib)Orphan drug

Array BioPharma Inc. (a wholly owned subsidiary of Pfizer Inc.)

12.1 Mechanism of Action Encorafenib is a kinase inhibitor that targets BRAF V600E, as well as wild-type BRAF and CRAF in in vitro cell-free assays wi...

Approved Oct 2023FDA label ↗

Tepmetko

(tepotinib)Orphan drug

EMD Serono, Inc.

12.1 Mechanism of Action Tepotinib is a kinase inhibitor that targets MET, including variants with exon 14 skipping alterations. Tepotinib inhibits he...

Approved Feb 2021FDA label ↗

LORBRENA

(Lorlatinib)Orphan drug

Pfizer, Inc.

Kinase Inhibitor [EPC]

12.1 Mechanism of Action Lorlatinib is a kinase inhibitor with in vitro activity against ALK and ROS1 as well as TYK1, FER, FPS, TRKA, TRKB, TRKC, FAK...

Approved Nov 2018FDA label ↗

VIZIMPRO

(dacomitinib)Orphan drug

Pfizer, Inc.

12.1 Mechanism of Action Dacomitinib is an irreversible inhibitor of the kinase activity of the human EGFR family (EGFR/HER1, HER2, and HER4) and cert...

Approved Sep 2018FDA label ↗

Gilotrif

(afatinib)Orphan drug

Boehringer Ingelheim Pharmaceuticals, Inc.

Kinase Inhibitor [EPC]

12.1 Mechanism of Action Afatinib covalently binds to the kinase domains of EGFR (ErbB1), HER2 (ErbB2), and HER4 (ErbB4) and irreversibly inhibits tyr...

Approved Jan 2018FDA label ↗

Alecensa

(alectinib)Orphan drug

Hoffmann-La Roche, Inc. (c/o Genentech, Inc.)

12.1 Mechanism of Action Alectinib is a tyrosine kinase inhibitor that targets ALK and RET. In nonclinical studies, alectinib inhibited ALK phosphoryl...

Approved Nov 2017FDA label ↗

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Clinical Trial Landscape

68 active trials
10Phase 3
1Phase 4
18Phase 2
8Phase 1
8N/A
16Unknown
7PHASE1, PHASE2
68Total recruiting
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