Diffuse intrinsic pontine glioma

Advocacy intelligence hub — real-time data for patient organizations

View full disease page →Search clinical trials →
Download CSV

At a Glance

Live from database

Regulatory Watchboard

10 events
Dec 2026Engineered HSV-1 M032 for the Treatment of Children and Adults With Newly Diagnosed Diffuse Midline Glioma After Standard of Care Radiation

M.D. Anderson Cancer Center — PHASE1

TrialNOT YET RECRUITING
Apr 2026PEP-CMV + Nivolumab for Newly Diagnosed Diffuse Midline Glioma/High-grade Glioma and Recurrent Diffuse Midline Glioma/High-grade Glioma, Medulloblastoma, and Ependymoma

Washington University School of Medicine — PHASE1, PHASE2

TrialNOT YET RECRUITING
Mar 2026H3K27M-specific Immune Effector Cells Targeting DMG/DIPG

Shenzhen Geno-Immune Medical Institute — PHASE1, PHASE2

TrialRECRUITING
Mar 2026Study of Tovorafenib in High-Grade Glioma and Diffuse Intrinsic Pontine Glioma (DIPG)

Nationwide Children's Hospital — PHASE2

TrialNOT YET RECRUITING
Jul 2025ACT001 for the Treatment of Diffuse Intrinsic Pontine Gliomas and H3K27-altered High Grade Gliomas

Nationwide Children's Hospital — PHASE2

TrialRECRUITING
Mar 2024CD200AR-L and Allogeneic Tumor Lysate Vaccine Immunotherapy for Recurrent HGG and Newly Diagnosed DMG/DIPG in Children and Young Adults

OX2 Therapeutics — PHASE1

TrialRECRUITING
Mar 2024Safety and Efficacy of Loco-regional B7H3 IL-7Ra CAR T Cell in DIPG

Chulalongkorn University — PHASE1

TrialRECRUITING
Oct 2023RE-irradiation of Diffuse MIdline Glioma paTients

Rigshospitalet, Denmark — NA

TrialNOT YET RECRUITING
Aug 2023CAR T Cells to Target GD2 for DMG

University College, London — PHASE1

TrialRECRUITING
Jun 2023FUS Etoposide for DMG

Columbia University — PHASE1

TrialRECRUITING

Data from FDA regulatory filings and ClinicalTrials.gov. Updated periodically.

Financial Assistance

FINANCIAL LANDSCAPE SUMMARY

0

Total programs

No financial assistance programs currently listed for Diffuse intrinsic pontine glioma.
Check the disease page for updates →

Approved Treatments

1 FDA-approved

Modeyso

(dordaviprone)Orphan drug

Chimerix, Inc.

12.1 Mechanism of Action Dordaviprone is a protease activator of the mitochondrial caseinolytic protease P (ClpP). Dordaviprone also inhibits the dopa...

FDA label ↗

View full treatment details on disease page →

Clinical Trial Landscape

27 active trials
1Phase 3
4Phase 2
13Phase 1
3Unknown
6PHASE1, PHASE2
27Total recruiting
Search clinical trials for Diffuse intrinsic pontine glioma

Recent News & Research

No recent news articles indexed yet for Diffuse intrinsic pontine glioma.
Search PubMed for Diffuse intrinsic pontine glioma

Browse all Diffuse intrinsic pontine glioma news →

Specialist Network

Top 6 by expertise

View all Diffuse intrinsic pontine glioma specialists →

Quick Actions