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Showing 20 of 23 recruiting trials for “diffuse-intrinsic-pontine-glioma

Phase 1, PHASE2RecruitingNCT07501156

H3K27M-specific Immune Effector Cells Targeting DMG/DIPG

🏥 Shenzhen Geno-Immune Medical Institute📍 1 site📅 Started Mar 2026View details ↗
Phase 2RecruitingNCT06838676

ACT001 for the Treatment of Diffuse Intrinsic Pontine Gliomas and H3K27-altered High Grade Gliomas

👨‍⚕️ David S. Ziegler, MD, FRACP, Sydney Children's Hospitals Network📍 20 sites📅 Started Jul 2025View details ↗
Phase 1RecruitingNCT06305910

CD200AR-L and Allogeneic Tumor Lysate Vaccine Immunotherapy for Recurrent HGG and Newly Diagnosed DMG/DIPG in Children and Young Adults

🏥 OX2 Therapeutics📍 1 site📅 Started Mar 2024View details ↗
Phase 1RecruitingNCT06221553

Safety and Efficacy of Loco-regional B7H3 IL-7Ra CAR T Cell in DIPG

👨‍⚕️ Piti Techavichit, MD, Chulalongkorn University📍 1 site📅 Started Mar 2024View details ↗
Phase 1RecruitingNCT05544526

CAR T Cells to Target GD2 for DMG

🏥 University College, London📍 1 site📅 Started Aug 2023View details ↗
Phase 1RecruitingNCT05762419

FUS Etoposide for DMG

👨‍⚕️ Stergios Zacharoulis, MD, Columbia University📍 1 site📅 Started Jun 2023View details ↗
Phase 1, PHASE2RecruitingNCT05630209

Blood Brain Barrier (BBB) Disruption Using Exablate Focused Ultrasound With Doxorubicin for Treatment of Pediatric Diffuse Intrinsic Pontine Gliomas (DIPG)

🏥 InSightec📍 3 sites📅 Started Jan 2023View details ↗
Phase 1RecruitingNCT05717712

Oncolytic Virus Ad-TD-nsIL12 for Primary Pediatric Diffuse Intrinsic Pontine Glioma

👨‍⚕️ Hongwei Zhang, Prof., Capital Medical University📍 1 site📅 Started Jan 2023View details ↗
Phase 1RecruitingNCT05717699

Oncolytic Virus Ad-TD-nsIL12 for Progressive Pediatric Diffuse Intrinsic Pontine Glioma

👨‍⚕️ Hongwei Zhang, Prof., Capital Medical University📍 1 site📅 Started Jan 2023View details ↗
Phase 1, PHASE2RecruitingNCT05615623

Blood Brain Barrier (BBB) Disruption Using Exablate Focused Ultrasound With Doxorubicin for Treatment of Pediatric DIPG

🏥 InSightec📍 1 site📅 Started Jan 2023View details ↗
Phase 3RecruitingNCT05476939

Biological Medicine for Diffuse Intrinsic Pontine Glioma (DIPG) Eradication 2.0

👨‍⚕️ Jacques GRILL, MD, PhD, Gustave Roussy, Cancer Campus, Grand Paris📍 50 sites📅 Started Sep 2022View details ↗
Phase 1, PHASE2RecruitingNCT05099003

A Study of the Drug Selinexor With Radiation Therapy in Patients With Newly-Diagnosed Diffuse Intrinsic Pontine (DIPG) Glioma and High-Grade Glioma (HGG)

👨‍⚕️ Adam L Green, Children's Oncology Group📍 127 sites📅 Started May 2022View details ↗
Phase 1, PHASE2RecruitingNCT04870944

CBL0137 for the Treatment of Relapsed or Refractory Solid Tumors, Including CNS Tumors and Lymphoma

👨‍⚕️ David S Ziegler, Pediatric Early Phase Clinical Trial Network📍 34 sites📅 Started Jan 2022View details ↗
Phase 1RecruitingNCT04943848

rHSC-DIPGVax Plus Checkpoint Blockade for the Treatment of Newly Diagnosed DIPG and DMG

👨‍⚕️ Ashley Plant-Fox, MD, Ann and Robert H. Lurie Children's Hospital📍 3 sites📅 Started Jan 2022View details ↗
Phase 2RecruitingNCT05009992

Combination Therapy for the Treatment of Diffuse Midline Gliomas

👨‍⚕️ Sabine Mueller, MD, PhD, University of California, San Francisco📍 20 sites📅 Started Oct 2021View details ↗
Phase 2RecruitingNCT05077735

Stereotactic Biopsy Split-Course Radiation Therapy in Diffuse Midline Glioma, SPORT-DMG Study

👨‍⚕️ Roman O. Kowalchuk, MD, Mayo Clinic in Rochester📍 2 sites📅 Started Oct 2021View details ↗
Phase 1RecruitingNCT04732065

ONC206 for Treatment of Newly Diagnosed, Recurrent Diffuse Midline Gliomas, and Other Recurrent Malignant CNS Tumors

👨‍⚕️ Sabine Mueller, MD, PhD, University of California, San Francisco📍 6 sites📅 Started Aug 2021View details ↗
Phase 1RecruitingNCT04196413

GD2 CAR T Cells in Diffuse Intrinsic Pontine Gliomas (DIPG) & Spinal Diffuse Midline Glioma(DMG)

👨‍⚕️ Michelle Monje, Stanford University📍 1 site📅 Started Jun 2020View details ↗
Phase 2RecruitingNCT04250064

A Study of Low Dose Bevacizumab With Conventional Radiotherapy Alone in Diffuse Intrinsic Pontine Glioma

👨‍⚕️ Rahul Krishnatry, Dr, Tata Memorial Hospital📍 1 site📅 Started Feb 2020View details ↗
Phase 1RecruitingNCT04099797

C7R-GD2.CAR T Cells for Patients With GD2-expressing Brain Tumors (GAIL-B)

👨‍⚕️ Jasia Mahdi, MD, Baylor College of Medicine📍 1 site📅 Started Feb 2020View details ↗
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