Amyotrophic Lateral Sclerosis (ALS)

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At a Glance

Live from database

Regulatory Watchboard

7 events
Jan 2026Intestinal Microbiome Transplant in ALS

Duke University — PHASE1, PHASE2

TrialRECRUITING
Dec 2024Transcranial Static Magnetic Stimulation (tSMS) and Potential Theranostic Biomarkers in Amyotrophic Lateral Sclerosis.

Campus Bio-Medico University — NA

TrialRECRUITING
Dec 2023A Phase 1, SAD and MAD Study to Evaluate the Safety and Tolerability of FB418

1ST Biotherapeutics, Inc. — PHASE1

TrialRECRUITING
Sep 2022

Relyvrio: FDA approved

Treatment of amyotrophic lateral sclerosis (ALS) in adults

FDAcompleted
Dec 2019

Tiglutik: FDA approved

TIGLUTIK is indicated for the treatment of amyotrophic lateral sclerosis (ALS).

FDAcompleted
Nov 2019

EXSERVAN: FDA approved

EXSERVAN is indicated for the treatment of amyotrophic lateral sclerosis (ALS).

FDAcompleted
May 2017

Radicava: FDA approved

Treatment of amyotrophic lateral sclerosis (ALS)

FDAcompleted

Data from FDA regulatory filings and ClinicalTrials.gov. Updated periodically.

Financial Assistance

3 programs

FINANCIAL LANDSCAPE SUMMARY

3

Total programs

3

Open now

3

Copay cards

Copay Assistance3

Radicava

Tanabe Pharma America Inc.

OpenContact for details

Relyvrio

Amylyx Pharmaceuticals, Inc.

OpenContact for details

EXSERVAN

Aquestive Therapeutics

OpenContact for details

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Approved Treatments

4 FDA-approved

Tiglutik

(riluzole oral suspension)Orphan drug

Italfarmaco SpA

Benzothiazole [EPC]

12.1 Mechanism of Action The mechanism by which riluzole exerts its therapeutic effects in patients with ALS is unknown.

Approved Dec 2019FDA label ↗

EXSERVAN

(riluzole oral film)Orphan drug

Aquestive Therapeutics

Approved Nov 2019

Radicava

(edaravone)Orphan drug

Tanabe Pharma America Inc.

12.1 Mechanism of Action The mechanism by which RADICAVA and RADICAVA ORS exert their therapeutic effect in patients with ALS is unknown.

Approved May 2017FDA label ↗

Qalsody

(tofersen)Orphan drugaccelerated

Biogen Inc.

Antisense Oligonucleotide [EPC]

12.1. Mechanism of Action Tofersen is an antisense oligonucleotide that causes degradation of SOD1 mRNA through binding to SOD1 mRNA, which results in...

FDA label ↗

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Clinical Trial Landscape

3 active trials
1Phase 1
1N/A
1PHASE1, PHASE2
3Total recruiting
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Recent News & Research

No recent news articles indexed yet for Amyotrophic Lateral Sclerosis (ALS).
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Specialist Network

Top 6 by expertise

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