Acquired generalized lipodystrophy

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At a Glance

Live from database

Regulatory Watchboard

10 events
Mar 2026Efficacy and Safety of Mibavademab in Adult and Pediatric Patients With Generalized Lipodystrophy

Regeneron Pharmaceuticals — PHASE3

TrialRECRUITING
May 2025Open-label Study to Evaluate Metreleptin in Children Under 6 Years of Age With Generalised Lipodystrophy

Amryt Pharma — PHASE3

TrialRECRUITING
Apr 2025Granzyme B-targeted PET Imaging Monitoring Tumor Responses to Immunotherapy

Zhongnan Hospital

TrialNOT YET RECRUITING
Mar 2025The Value of PET Imaging Targeting Granzyme B in Predicting Efficacy and Prognosis in T-NK Cell Lymphoma

Ruijin Hospital

TrialNOT YET RECRUITING
Dec 2024A Study of the Safety of Mibavademab in Pediatric and Adult Participants Switching From Metreleptin to Mibavademab for the Treatment of Generalized Lipodystrophy (GLD)

Regeneron Pharmaceuticals — PHASE3

TrialACTIVE NOT RECRUITING
Nov 2024GzmB-PET/CT to Evaluate Neoadjuvant Therapy Efficacy in Breast Cancer

Shanghai Jiao Tong University School of Medicine

TrialRECRUITING
May 202364Cu-GRIP B in Patients With Advanced Malignancies

Rahul Aggarwal — PHASE1, PHASE2

TrialRECRUITING
Aug 2020Pulmonary Hypertension Biorepository and Registry

University of Kansas Medical Center

TrialRECRUITING
Apr 2019Cyclophosphamide in the Treatment of Associated Acquired Lipodystrophy Syndrome With Type 1 Diabetes

Children's Hospital of Fudan University — NA

TrialACTIVE NOT RECRUITING
Dec 2017Registry for Patients With Lipodystrophy

University of Ulm

TrialRECRUITING

Data from FDA regulatory filings and ClinicalTrials.gov. Updated periodically.

Financial Assistance

1 program

FINANCIAL LANDSCAPE SUMMARY

1

Total programs

1

Open now

Patient Assistance Programs1

MYALEPT

Chiesi Farmaceutici S.p.A.

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Approved Treatments

1 FDA-approved

MYALEPT

(metreleptin)Orphan drugstandard

Chiesi Farmaceutici S.p.A.

Leptin Analog [EPC]

12.1 Mechanism of Action Adipocytes store lipids to meet the fuel requirements of non-adipose tissues during fasting. In patients with generalized lip...

FDA label ↗

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Clinical Trial Landscape

6 active trials
4Phase 3
1N/A
1Unknown
6Total recruiting
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Recent News & Research

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Specialist Network

Top 6 by expertise

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