🧪 UPDATED DAILY FROM CLINICALTRIALS.GOVSynced Apr 1

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52+ recruiting trials across all rare diseases. Filter by phase, location, and condition.

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Showing 20 of 52 recruiting trials for “primary-localized-amyloidosis

Phase 3RecruitingNCT06963216

A Study Investigating Coagadex in the Treatment AFXD Associated With AL Amyloidosis

👨‍⚕️ Mirella Calcinai, MD, Medical Director, Clinical Development📍 3 sites📅 Started Feb 2026View details ↗
Phase 3RecruitingNCT07388602

A Study to Evaluate the Safety and Efficacy of SCTC21C in Combination With Bortezomib, Cyclophosphamide, and Dexamethasone in Patients With Newly Diagnosed Systemic Light-Chain Amyloidosis (NDSLCA)

🏥 Sinocelltech Ltd.📍 1 site📅 Started Jan 2026View details ↗
Phase 1, PHASE2RecruitingNCT07266116

Assessment of the Efficacy and Safety of Injectable TQB2934 (Subcutaneous Injection) in Systemic Light Chain Amyloidosis Patients

🏥 Shanghai Chia Tai Tianqing Pharmaceutical Technology Development Co., Ltd.📍 23 sites📅 Started Dec 2025View details ↗
RecruitingNCT07448935

One Gene, Two Diseases: the Pathologic Role of IGLV1-44 in AL Amyloidosis and POEMS

🏥 Fondazione IRCCS Policlinico San Matteo di Pavia📍 1 site📅 Started Nov 2025View details ↗
RecruitingNCT07448779

Investigating the Pathogenic Role of N-glycosylation in AL Amyloidosis: Molecular Bases, Diagnosis, and Treatment

🏥 Fondazione IRCCS Policlinico San Matteo di Pavia📍 1 site📅 Started Nov 2025View details ↗
Phase 2RecruitingNCT07110844

Teclistamab-Daratumumab in AL Amyloidosis

👨‍⚕️ Suzanne Lentzsch, MD, PhD, Columbia University📍 1 site📅 Started Nov 2025View details ↗
Phase 1RecruitingNCT07250269

Study of GC012F, CAR-T Therapy Targeting CD19 and BCMA in Chinese Participants With Relapsed or Refractory AL Amyloidosis

🏥 Gracell Biotechnologies (Shanghai) Co., Ltd.📍 9 sites📅 Started Oct 2025View details ↗
RecruitingNCT07172243

BE.Amycon Biobank & Data Registry UZ Leuven

👨‍⚕️ Michel Delforge, UZ Leuven Gasthuisberg📍 2 sites📅 Started Sep 2025View details ↗
Phase 1RecruitingNCT06974877

Repeat PET/CT Imaging in People With CAPS and Anakinra-Induced Amyloidosis Using an Amyloid-Reactive Peptide to Measure Changes in Organ-Specific Amyloid Load

👨‍⚕️ Sara Alehashemi, M.D., National Institute of Allergy and Infectious Diseases (NIAID)📍 1 site📅 Started Sep 2025View details ↗
Phase 2RecruitingNCT07151690

BCMA/CD3 Bispecific Antibody Treatment for Newly Diagnosed Amyloidosis

🏥 Institute of Hematology & Blood Diseases Hospital, China📍 1 site📅 Started Sep 2025View details ↗
Phase 1, PHASE2RecruitingNCT07081646

A Phase 1b/2 Study of CAR T Cell Therapy Targeting CD19 and BCMA in Participants With Relapsed or Refractory AL Amyloidosis.

🏥 Alexion Pharmaceuticals, Inc.📍 18 sites📅 Started Aug 2025View details ↗
Phase 2RecruitingNCT07039578

Study Evaluating the Efficacy and Safety of CM336 Injection in the Treatment of Light-Chain Amyloidosis

👨‍⚕️ Jian Li, Peking Union Medical College Hospital📍 2 sites📅 Started Jul 2025View details ↗
RecruitingNCT07232459

[18F]FT8 PET Imaging in Immunoglobulin Light Chain Amyloidosis

🏥 Tianjin Medical University📍 2 sites📅 Started Jul 2025View details ↗
Phase 2RecruitingNCT06649695

A Phase II Trial of Teclistamab in Participants With Previously Treated Immunoglobulin Light-chain (AL) Amyloidosis

👨‍⚕️ Murielle Roussel, MD, CHU Limoges📍 10 sites📅 Started Jul 2025View details ↗
Phase 2RecruitingNCT07079423

Teclistamab in Newly Diagnosed Mayo Stage IIIB AL Amyloidosis

🏥 Peking Union Medical College Hospital📍 1 site📅 Started Jun 2025View details ↗
EARLY_Phase 1RecruitingNCT07085559

Safety and Efficacy of Metabolically Armed BCMA CAR-T Cells (Meta10-BCMA) in the Treatment of r/r Plasma Cell Neoplasms Clinical Research

🏥 Anhui Provincial Hospital📍 1 site📅 Started Jun 2025View details ↗
Phase 2RecruitingNCT06935162

Teclistamab in Previously Treated AL Amyloidosis

🏥 Peking Union Medical College Hospital📍 1 site📅 Started May 2025View details ↗
NARecruitingNCT06699394

Prospective Study of Teclistamab in the Treatment of Systemic AL Amyloidosis

👨‍⚕️ Jin Lu, M.D., Peking University People's Hospital📍 2 sites📅 Started Mar 2025View details ↗
Phase 2RecruitingNCT06971380

Study of HBI0101 (NXC-201) CAR-T Therapy in Multiple Myeloma and Light-Chain Amyloidosis

🏥 Polina Stepensky📍 1 site📅 Started Mar 2025View details ↗
RecruitingNCT06354322

Unclassified GENotypes of Autoinflammatory Diseases and AA Amyloidosis

🏥 Assistance Publique - Hôpitaux de Paris📍 1 site📅 Started Feb 2025View details ↗
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