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25+ recruiting trials across all rare diseases. Filter by phase, location, and condition.

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Showing 20 of 25 recruiting trials for “high-grade-astrocytoma

Phase 2RecruitingNCT07417761

Tuvusertib in Astrocytoma With ATRX Mutation

👨‍⚕️ Estela Pineda, M.D.; Ph.D., Medical Oncology, Hospital Clínic de Barcelona📍 10 sites📅 Started Dec 2025View details ↗
NARecruitingNCT06930846

HOBSCOTCH-CA (HOme-Based Self-management and COgnitive Training CHanges Lives in Brain CAncer)

👨‍⚕️ Elaine T Kiriakopoulos, MD, MPH, MSc, Dartmouth-Health/Dartmouth-Hitchcock, Dartmouth College📍 1 site📅 Started Nov 2025View details ↗
Phase 2RecruitingNCT06776250

Study of How Safe and Effective Tarlatamab is in Brain Cancers

👨‍⚕️ Eric Chen, MD, Princess Margaret Cancer Centre/University Health Network📍 1 site📅 Started Aug 2025View details ↗
EARLY_Phase 1RecruitingNCT06333899

Lorlatinib for Newly-Diagnosed High-Grade Glioma With ROS or ALK Fusion

👨‍⚕️ Hamza Gorsi, MD, Children's Hospital of Michigan📍 18 sites📅 Started Aug 2025View details ↗
Phase 1, PHASE2RecruitingNCT05956821

Treatment of Relapsed/Refractory Intracranial Glioma in Patients Under 22 Years of Age

👨‍⚕️ Heather McCrea, MD, University of Miami📍 1 site📅 Started Jun 2025View details ↗
Phase 1RecruitingNCT06894979

Testing the Addition of an Anti-Cancer Drug, AZD1390, During Radiation Therapy for Newly Diagnosed High Grade Glioma, Diffuse Midline Glioma, or Diffuse Intrinsic Pontine Glioma

👨‍⚕️ Erin K Barr, Pediatric Early Phase Clinical Trial Network📍 17 sites📅 Started Jun 2025View details ↗
Phase 2RecruitingNCT06161974

Study of Olutasidenib and Temozolomide in HGG

👨‍⚕️ Santosh Valvi, FRACP, MSc, Perth Children's Hospital📍 18 sites📅 Started Mar 2025View details ↗
RecruitingNCT06915649

Exploration and Evaluation of Amygdalo-Hippocampectomy According to Prof. Coubes' Technique: An Anatomical, Clinical, and Educational Approach

👨‍⚕️ Gaetan POULEN, MD, PhD, CHU de MONTPELLIER, FRANCE📍 1 site📅 Started Aug 2024View details ↗
Phase 2RecruitingNCT05843253

Study of Ribociclib and Everolimus in HGG and DIPG or Ribociclib and Temozolomide in DHG, H3G34-mutant

👨‍⚕️ Margot Lazow, MD, Nationwide Children's Hospital📍 21 sites📅 Started Aug 2024View details ↗
RecruitingNCT05839379

Targeted Pediatric High-Grade Glioma Therapy

👨‍⚕️ Maryam Fouladi, MD, Nationwide Children's Hospital📍 21 sites📅 Started Aug 2024View details ↗
Phase 2RecruitingNCT06264388

DB107-Retroviral Replicating Vector (RRV) Combined With DB107-Flucytosine (FC) in Patients With Recurrent Glioblastoma or Anaplastic Astrocytoma

👨‍⚕️ Ashish Shah, MD, University of Miami📍 1 site📅 Started May 2024View details ↗
Phase 1, PHASE2RecruitingNCT06047379

Safety and Efficacy of NEO212 in Patients With Astrocytoma IDH-mutant, Glioblastoma IDH-wildtype or Brain Metastasis

👨‍⚕️ Tom Chen, MD, PhD, NeOnc Technologies📍 6 sites📅 Started Nov 2023View details ↗
Phase 1RecruitingNCT05879367

Evaluation of Eflornithine Plus Temozolomide in Patients With Newly Diagnosed Glioblastoma or Astrocytoma

👨‍⚕️ Howard Colman, MD, PhD, Huntsman Cancer Institute/ University of Utah📍 8 sites📅 Started Jul 2023View details ↗
Phase 1RecruitingNCT05698524

A Study of Temodar With Abexinostat (PCI-24781) for Patients With Recurrent Glioma

👨‍⚕️ Nicole A Shonka, MD, University of Nebraska📍 1 site📅 Started Jun 2023View details ↗
Phase 1, PHASE2RecruitingNCT05084430

Study of Pembrolizumab and M032 (NSC 733972)

👨‍⚕️ James Markert, MD, The University of Alabama at Birmingham📍 1 site📅 Started Feb 2022View details ↗
EARLY_Phase 1RecruitingNCT04135807

Implantable Microdevice In Primary Brain Tumors

👨‍⚕️ Pier Paolo Peruzzi, MD, PhD, Brigham and Women's Hospital📍 1 site📅 Started Mar 2020View details ↗
Phase 2RecruitingNCT04623931

Chemotherapy and Radiation Therapy for the Treatment of IDH Wildtype Gliomas or Non-histological (Molecular) Glioblastomas

👨‍⚕️ Debra N Yeboa, M.D. Anderson Cancer Center📍 1 site📅 Started Jan 2020View details ↗
Phase 1RecruitingNCT03911388

HSV G207 in Children With Recurrent or Refractory Cerebellar Brain Tumors

👨‍⚕️ Gregory Friedman, MD, M.D. Anderson Cancer Center📍 3 sites📅 Started Sep 2019View details ↗
NARecruitingNCT03861299

The SAFE-Trial: Awake Craniotomy Versus Surgery Under General Anesthesia for Glioblastoma Patients.

👨‍⚕️ Arnaud Vincent, MD PhD, Erasmus Medical Center📍 5 sites📅 Started Apr 2019View details ↗
Phase 1RecruitingNCT03896568

MSC-DNX-2401 in Treating Patients With Recurrent High-Grade Glioma

👨‍⚕️ Frederick F Lang, M.D. Anderson Cancer Center📍 1 site📅 Started Feb 2019View details ↗
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