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Showing 20 of 98 recruiting trials for “Squamous cell carcinoma of the esophagus

Phase 2RecruitingNCT07457528

Efficacy and Safety of Neo-CRT Plus Serplulimab, Nimotuzumab in Patients With Locally Advanced Resectable ESCC

🏥 Tianjin Medical University Cancer Institute and Hospital📍 1 site📅 Started Mar 2026View details ↗
Phase 2RecruitingNCT07331155

A Phase II Clinical Study of LBL-024 Combination Therapy in Patients With Advanced Solid Tumour[Substudy 03(ESCC)]

👨‍⚕️ Lin Shen, Peking University Cancer Hospital & Institute📍 7 sites📅 Started Feb 2026View details ↗
Phase 1RecruitingNCT07503808

A Study of IDE034 in Adult Participants With Locally Advanced/Metastatic Solid Tumors Types

🏥 IDEAYA Biosciences📍 5 sites📅 Started Feb 2026View details ↗
Phase 2RecruitingNCT07403136

Vebrekotuzumab ± Anti-PD-1 in Pretreated Advanced ESCC

🏥 Fudan University📍 1 site📅 Started Feb 2026View details ↗
Phase 1, PHASE2RecruitingNCT07385001

A Prospective, Multicenter, Phase Ib/II Trial of Ivonescimab (AK112) Combined With Albumin-Paclitaxel and Cisplatin as Neoadjuvant Therapy for ESCC

🏥 Tang-Du Hospital📍 1 site📅 Started Jan 2026View details ↗
Phase 2RecruitingNCT07263919

Perioperative Cadonilimab Combined With Neoadjuvant Chemotherapy in Resectable Esophageal Squamous Cell Carcinoma (ESCC)

👨‍⚕️ Xiaolong Yan, The Second Affiliated Hospital of Air Force Medical University📍 1 site📅 Started Dec 2025View details ↗
Phase 2RecruitingNCT07481058

KC1036 in Combination With PD-1 Antibody and Platinum-based Chemotherapy for First-line Advanced Esophageal Cancer

🏥 Beijing Konruns Pharmaceutical Co., Ltd.📍 1 site📅 Started Dec 2025View details ↗
Phase 1RecruitingNCT07217171

A Study Evaluating the Safety, Efficacy, and Pharmacokinetics (PK) of EVOLVE104 in Participants With Advanced Urothelial and Squamous Cell Carcinomas

👨‍⚕️ EvolveImmune Study Team, EvolveImmune United, Inc📍 8 sites📅 Started Nov 2025View details ↗
Phase 2Enrolling by InvitationNCT07312578

Nimotuzumab,Camrelizumab, and Neoadjuvant Chemotherapy(nCT) in the Treatment of Esophageal Squamous Cell Carcinoma

👨‍⚕️ Zhihao MM Lu, PHD, Peking University Cancer Hospital & Institute📍 1 site📅 Started Nov 2025View details ↗
Phase 2RecruitingNCT07039162

Study of Tislelizumab Combined With Chemoradiotherapy and Surgery for Unresectable Esophageal Squamous Cell Carcinoma

🏥 Ming-Yu Lien📍 8 sites📅 Started Sep 2025View details ↗
Phase 2RecruitingNCT07290010

The Efficacy and Safety of Iparomlimab and Tuvonralimab Injection Combined With Chemotherapy as the First-line Treatment for Esophageal Squamous Cell Carcinoma

🏥 Hebei Medical University Fourth Hospital📍 1 site📅 Started Sep 2025View details ↗
Phase 1, PHASE2RecruitingNCT06753747

A Trial of the Combination of Afatinib and Palbociclib in Previously Treated Advanced Esophageal Squamous Cell Carcinoma

👨‍⚕️ Jin Zhou, West China Hospital📍 1 site📅 Started Sep 2025View details ↗
Phase 1RecruitingNCT07085091

A First in Human Study of ALX2004 With Advanced or Metastatic Selected Solid Tumors

🏥 ALX Oncology Inc.📍 7 sites📅 Started Aug 2025View details ↗
Phase 2RecruitingNCT07162506

DCRT vs. Surgery in Resectable ESCC Patient Achiving cCR/PR After nCI

👨‍⚕️ Wencheng Zhang, M.D., Tianjin Cancer Hospital📍 1 site📅 Started Aug 2025View details ↗
Phase 1, PHASE2RecruitingNCT06780111

Substudy 06E: Umbrella Study of Combination Therapies in Esophageal Cancer (MK-3475-06E/KEYMAKER-U06)

👨‍⚕️ Medical Director, Merck Sharp & Dohme LLC📍 42 sites📅 Started Jul 2025View details ↗
Phase 2RecruitingNCT06764355

Neoadjuvant Immunochemotherapy and Chemoradiotherapy Followed by Surgery for Advanced Esophageal Squamous Cell Carcinoma

🏥 National Taiwan University Hospital📍 1 site📅 Started Jul 2025View details ↗
Phase 2RecruitingNCT07086469

Surufatinib in Combination With Neoadjuvant Chemo-immunotherapy and Concurrent Chemoradiotherapy for Patients With Unresectable Locally Advanced Esophageal Squamous Cell Carcinoma

👨‍⚕️ Hui Liu, Sun yat-sen universtiy cancer center📍 1 site📅 Started Jul 2025View details ↗
Phase 1RecruitingNCT07317609

Neoadjuvant Immunotherapy Combined With Chemotherapy Sequenced With Endoscopic Resection for Esophageal Cancer (Endosurgery-02)

🏥 Shanghai Zhongshan Hospital📍 1 site📅 Started Jul 2025View details ↗
Phase 2RecruitingNCT07188103

Ivonescimab Plus Short-Course Hypofractionated Radiotherapy as Second-Line Therapy for Esophageal Squamous Cell Carcinoma

🏥 Anhui Provincial Hospital📍 1 site📅 Started Jul 2025View details ↗
Phase 1RecruitingNCT07359417

MR-Guided Radiotherapy Dose Escalation Trial for Esophageal Squamous Cell Carcinoma

🏥 UMC Utrecht📍 1 site📅 Started May 2025View details ↗
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