🧪 UPDATED DAILY FROM CLINICALTRIALS.GOVSynced Apr 1

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8+ recruiting trials across all rare diseases. Filter by phase, location, and condition.

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Showing 8 of 8 recruiting trials for “PIK3CA-related overgrowth syndrome

Phase 2RecruitingNCT06997588

EPIK-P4: A Phase II Single-arm Study to Assess the Efficacy, Safety and Pharmacokinetics of Alpelisib (BYL719) in Pediatric and Adult Patients With PIK3CA-related Overgrowth Spectrum (PROS)

👨‍⚕️ Novartis Pharmaceuticals, Novartis Pharmaceuticals📍 22 sites📅 Started Oct 2025View details ↗
NARecruitingNCT06840015

Use of Airpod Pros as Assistive Technology

👨‍⚕️ Linda Thibodeau, Ph.D., The University of Texas at Dallas📍 1 site📅 Started Jul 2025View details ↗
Phase 2RecruitingNCT06789913

A Phase 2 Study of Mutant-selective PI3Kα Inhibitor, RLY-2608, in Adults and Children With PIK3CA Related Overgrowth Spectrum and Malformations Driven by PIK3CA Mutation

🏥 Relay Therapeutics, Inc.📍 25 sites📅 Started Jun 2025View details ↗
RecruitingNCT06956248

Innovating Access to Novel Therapies Through Standardized Prospective Integration of Response Evaluations (IMPACT-INSPIRE)

👨‍⚕️ Daniel SW Tan, BSc(Hons), MBBS, MRCP, PhD, National Cancer Centre, Singapore📍 1 site📅 Started Sep 2024View details ↗
RecruitingNCT06364579

Patient Reported Outcomes (PROs) in Anal Cancer Patient Treated by Intensity Modulated Radiotherapy (IMRT).

👨‍⚕️ Stefania Manfrida, Fondazione Policlinico Universitario A. Gemelli, IRCCS📍 1 site📅 Started Mar 2024View details ↗
Phase 1, PHASE2RecruitingNCT06975618

Study to Evaluate the Safety, Tolerability, Pharmacokinetics and Preliminary Efficacy of CYH33 in Patients With PIK3CA-related Overgrowth Spectrum (PROS) and PIK3CA-related Vascular Malformations (PRVM)

🏥 Haihe Biopharma Co., Ltd.📍 4 sites📅 Started Aug 2023View details ↗
RecruitingNCT05898932

Enhanced Clinical Decisions for Management of Benign Prostatic Hyperplasia Using Patient-Reported Outcomes

👨‍⚕️ James W. Griffith, PhD, University of Chicago📍 1 site📅 Started Jun 2023View details ↗
Phase 2RecruitingNCT04356209

Improving Theempowerment in Patients With Severe Breast Fibrosis Radio-induced Treated by Pravastatin : Benefit of e-PROs (Electronic " Patient Reported Outcome ") on Breast-related Quality of Life

🏥 Institut du Cancer de Montpellier - Val d'Aurelle📍 1 site📅 Started Jan 2020View details ↗

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