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Showing 20 of 63 recruiting trials for “Clear cell renal carcinoma

Phase 1RecruitingNCT07128680

Immunotherapy (Nivolumab and Ipilimumab) With and Without a Live Biotherapeutic Product (EXL01) for the Treatment of Metastatic Renal Cell Cancer

👨‍⚕️ Sumanta K Pal, City of Hope Medical Center📍 2 sites📅 Started Apr 2026View details ↗
Phase 2RecruitingNCT06863311

Trial of Zanzalintinib (XL092) in Combination With Immunotherapy in Patients Who Progress on Adjuvant Therapy in Clear Cell RCC

👨‍⚕️ Karie Runcie, MD, Columbia University📍 2 sites📅 Started Mar 2026View details ↗
Phase 2RecruitingNCT07397611

Pre-NEOSHIFT-RCC: Neoadjuvant HIF-Inhibitor Immunotherapy in RCC

👨‍⚕️ Wenxin Xu, MD, Dana-Farber Cancer Institute📍 3 sites📅 Started Mar 2026View details ↗
Phase 2RecruitingNCT07188896

A Randomized Trial of Fianlimab and Cemiplimab +/- Ipilimumab or Ipilimumab Plus Nivolumab in First-line Advanced Renal Cell Carcinoma (RCC)

👨‍⚕️ Brian Rini, MD, Vanderbilt-Ingram Cancer Center📍 1 site📅 Started Mar 2026View details ↗
Phase 2RecruitingNCT07469683

An Open-label, Randomized Phase 2 Clinical Trial to Evaluate the Efficacy and Safety of the Combination Therapy of SLC-3010 and Axitinib Compared to Axitinib Monotherapy as a Second-line Treatment for Locally Advanced or Metastatic Clear Cell Renal Cell Carcinoma

🏥 Yonsei University📍 1 site📅 Started Mar 2026View details ↗
Phase 1, PHASE2RecruitingNCT07227415

A Study to Learn About the Medicine Called PF-08634404 Dosed Alone and in Combination With Other Anticancer Therapies in Adults With Locally Advanced or Metastatic Renal Cell Cancer

👨‍⚕️ Pfizer CT.gov Call Center, Pfizer📍 14 sites📅 Started Feb 2026View details ↗
Phase 2RecruitingNCT07223541

Cemiplimab or Cemiplimab and Fianlimab After Stereotactic Body Radiotherapy in Clear Cell Renal Cell Carcinoma

👨‍⚕️ Adanma Ayanambakkam, MD, University of Oklahoma📍 1 site📅 Started Jan 2026View details ↗
Phase 2RecruitingNCT07187778

Phase II Trial of Single Agent Belzutifan or Pembrolizumab Versus Combination as Neoadjuvant Therapy in Clear Cell Renal Cell Carcinoma (BLAZE)

👨‍⚕️ Eric Jonasch, MD, M.D. Anderson Cancer Center📍 1 site📅 Started Dec 2025View details ↗
Phase 1RecruitingNCT07300241

Open-Label Phase 1/2 Study of NEO-811 in Subjects With Locally Advanced or Metastatic Non-Resectable Clear Cell Renal Cell Carcinoma

👨‍⚕️ Klaus Wagner, MD, PhD, Neomorph, Inc📍 7 sites📅 Started Dec 2025View details ↗
Phase 2RecruitingNCT07123090

A Study of Sasanlimab, Palbociclib and Axitinib in Metastatic Renal Cell Carcinoma

👨‍⚕️ Stephanie Berg, DO, Dana-Farber Cancer Institute📍 2 sites📅 Started Nov 2025View details ↗
Phase 2RecruitingNCT07389629

Iparomlimab and Tuvonralimab (QL1706) Combination With Lenvatinib as Neoadjuvant Therapy for ccRCC

🏥 Sun Yat-sen University📍 1 site📅 Started Nov 2025View details ↗
RecruitingNCT07240610

Abscopal Effect of Ultra-Hypofractionated Radiation Plus Immunotherapy in Metastatic Renal Cell Carcinoma

👨‍⚕️ Hiroshi Onishi, MD, PhD, University of Yamanashi📍 1 site📅 Started Nov 2025View details ↗
Phase 2Enrolling by InvitationNCT07488572

Safety and Efficacy of Yiwoxidan Anti (AK112) Monotherapy in Patients With Metastatic Renal Clear Cell Carcinoma Who Are Intolerant to TKI Treatment: a Prospective, Single Arm, Phase II Clinical Study

🏥 Sun Yat-sen University📍 1 site📅 Started Nov 2025View details ↗
Phase 2RecruitingNCT06794229

Neoadjuvant Zanzalintinib Plus Nivolumab in Patients With Locally Advanced and/or Inoperable Clear Cell Renal Cell Carcinoma With or Without Non-measurable Metastasis

👨‍⚕️ Qian Qin, MD, University of Texas📍 1 site📅 Started Oct 2025View details ↗
RecruitingNCT07234656

Patient-partnered Research in Investigating Fear of Cancer Recurrence in Kidney Cancer

👨‍⚕️ Brigitta R Villumsen, PhD, Gødstrup Hospital📍 3 sites📅 Started Sep 2025View details ↗
Phase 1RecruitingNCT07072234

Phase I Study of Allogeneic Transforming Growth Factor-beta Receptor Type 2 Knockout CD70 CAR NK Cells in Treatment Refractory Clear Cell Renal Cell Carcinoma

👨‍⚕️ Andrew C Johns, MD, M.D. Anderson Cancer Center📍 1 site📅 Started Sep 2025View details ↗
Phase 1RecruitingNCT07179770

Effects of Belzutifan on 89Zr-DFO-girentuximab PET Uptake in Patients With Renal Cell Carcinoma (RCC)

👨‍⚕️ Minas Economides, MD, NYU Langone Health📍 1 site📅 Started Sep 2025View details ↗
Phase 3RecruitingNCT07011719

Study of Casdatifan and Cabozantinib Versus Placebo and Cabozantinib in Patients With Advanced Clear Cell Renal Cell Carcinoma

👨‍⚕️ Medical Director, Arcus Biosciences📍 29 sites📅 Started Sep 2025View details ↗
Phase 1, PHASE2RecruitingNCT06866262

Inulin Gel in Combination With Ipilimumab and Nivolumab for the Treatment of Metastatic or Locally Advanced Kidney Cell Cancer, ICON Trial

👨‍⚕️ Ulka N Vaishampayan, University of Michigan Rogel Cancer Center📍 1 site📅 Started Aug 2025View details ↗
Phase 1, PHASE2RecruitingNCT07049926

Substudy 03C: A Study of Combination Therapies in Participants With Renal Cell Carcinoma With Recurrent Disease During or After Anti-PD-(L)1 Therapy (MK-3475-03C/KEYMAKER-U03)

👨‍⚕️ Medical Director, Merck Sharp & Dohme LLC📍 27 sites📅 Started Jul 2025View details ↗
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