RecruitingPHASE1, PHASE2NCT07187401
A First-in-Human Safety and Efficacy Study of ALN-CFB, a Small Interfering RNA (siRNA) Targeting Complement Factor B, in Adult Participants With Paroxysmal Nocturnal Hemoglobinuria With Persistent Anemia on a C5 Inhibitor
Studying Paroxysmal nocturnal hemoglobinuria
Last synced from ClinicalTrials.gov
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Clinical trial records are synced from ClinicalTrials.gov through automated extraction.
Report missing dataKey facts
- Sponsor
- Regeneron Pharmaceuticals
- Principal Investigator
- Clinical Trial ManagementRegeneron Pharmaceuticals
- Intervention
- ALN-CFB(drug)
- Enrollment
- 24 enrolled
- Eligibility
- 18 years · All sexes
- Timeline
- 2026 – 2031
Study locations (7)
- Toronto General Hospital, Toronto, Ontario, Canada
- St. Vincent Hospital - The Catholic University of Korea, Suwon, Gyeonggi-do, South Korea
- Seoul National University Hospital, Seoul, South Korea
- The Catholic University of Korea, Seoul St. Mary's Hospital, Seoul, South Korea
- Severance Hospital, Seoul, South Korea
- Samsung Medical Center, Seoul, South Korea
- St. James's University Hospital, Leeds, West Yorkshire, United Kingdom
Primary source
Recruitment status, site addresses, contacts, and full eligibility criteria can change between syncs. Always verify with the trial team before planning travel or treatment.
Open NCT07187401 on ClinicalTrials.govOther trials for Paroxysmal nocturnal hemoglobinuria
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