Active, not recruitingPhase 3NCT05537220

Oral N-acetylcysteine for Retinitis Pigmentosa

Studying Retinitis pigmentosa

Last synced from ClinicalTrials.gov May 7, 2026

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Key facts

Sponsor: Johns Hopkins University
Principal Investigator: Peter A Campochiaro, MD
Johns Hopkins University
Intervention: N-acetylcysteine(drug)
Enrollment: 485 enrolled
Eligibility: 18-65 years · All sexes
Timeline: 2023 – 2030

Study locations (30)

University of California - Davis, Department of Ophthalmology & Vision Science, Davis, California, United States
University of Southern California, Keck School of Medicine, Los Angeles, California, United States
University of California - San Francisco, Department of Ophthalmology, San Francisco, California, United States
Stanford University, Byers Eye Institute, Stanford, California, United States
Vitreo Retinal Associates, Gainesville, Florida, United States
University of Florida - Jacksonville, UF Health Jacksonville, Jacksonville, Florida, United States
University of Miami, Bascom Palmer Eye Institute, Miami, Florida, United States
Emory University, Emory Eye Center, Atlanta, Georgia, United States
University Of Illinois At Chicago, Chicago, Illinois, United States
Northwestern University, Evanston, Illinois, United States
University of Iowa, Carver College of Medicine, Iowa City, Iowa, United States
Wilmer Eye Institute- Johns Hopkins University, Baltimore, Maryland, United States
Harvard University, Mass. Eye and Ear, Boston, Massachusetts, United States
University of Michigan, Kellogg Eye Center, Ann Arbor, Michigan, United States
University of Minnesota, Department of Ophthalmology and Visual Neurosciences, Minneapolis, Minnesota, United States
+15 more locations on ClinicalTrials.gov

Collaborators

National Eye Institute (NEI) · Duke University · Emory University · Massachusetts Eye and Ear Infirmary · Mayo Clinic · Medical College of Wisconsin · Retina Foundation of the Southwest · Stanford University · University of California, Davis · University of Florida · University of Iowa · University of Miami · University of Michigan · University of Minnesota · University of Oklahoma · University of Southern California · University of Utah · University of Washington · University of Wisconsin, Madison · Vanderbilt University · Vitreo Retinal Associates, PA · University of Houston · Medical University of Graz · McGill University · Universität Tübingen · Radboud University Medical Center · University of Amsterdam · University Hospital, Basel, Switzerland · University College London Hospitals · Northwestern University · University of Pennsylvania

Primary source

Recruitment status, site addresses, contacts, and full eligibility criteria can change between syncs. Always verify with the trial team before planning travel or treatment.

Open NCT05537220 on ClinicalTrials.gov

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