Limbal Stem Cell Deficiency (LSCD) Treatment With Cultivated Stem Cell (CALEC) Graft

Key facts

Sponsor

Massachusetts Eye and Ear Infirmary

Principal Investigator

Ula Jurkunas, MD

Massachusetts Eye and Ear Infirmary

Intervention

Biopsy to collect limbal epithelial stem cells that will be cultivated into a graft(procedure)

Enrollment

23 enrolled

Eligibility

18-89 years · All sexes

Timeline

2016 – 2023

Study locations (1)

• Massachusetts Eye and Ear Infirmary, Boston, Massachusetts, United States

Collaborators

Dana-Farber Cancer Institute

Primary source

Recruitment status, site addresses, contacts, and full eligibility criteria can change between syncs. Always verify with the trial team before planning travel or treatment.

Other trials for Limbal stem cell deficiency

Additional recruiting or active studies for the same condition.

• RECRUITINGNCT07119580
  Association Between Limbal Function and Tear Proteomics in Chronic Ocular Diseases: Focusing on Glaucoma
  National Taiwan University Hospital
• RECRUITINGNANCT06265298
  Implementation of a Protocol for the Transdifferentiation of Buccal Mucosal Epithelium Into Corneal Epithelium
  University Hospital, Montpellier
• RECRUITINGPHASE1NCT06452316
  Study to Evaluate the Safety and Efficacy of CSB-001 Ophthalmic Solution 0.1% in Subjects With Limbal Stem Cell Deficiency
  Claris Biotherapeutics, Inc.
• RECRUITINGNANCT04995926
  Labial Mucosal Epithelium Grafting for Corneal Limbus Substitution
  The S.N. Fyodorov Eye Microsurgery State Institution
• RECRUITINGPHASE1, PHASE2NCT03949881
  Cultured Autologous Oral Mucosa Epithelial Sheet for the Treatment of Bilateral Limbal Stem Cell Deficiency
  Hospices Civils de Lyon
• ACTIVE NOT RECRUITINGPHASE1NCT03957954
  Stem Cell Therapy for Limbal Stem Cell Deficiency
  University of California, Los Angeles
• RECRUITINGNCT02886611
  Limbal Stem Cell Deficiency of Genetic Origin: Genotype-phenotype Correlation
  Fondation Ophtalmologique Adolphe de Rothschild
• RECRUITINGNANCT01756365
  Autologous Cultured Corneal Epithelium (CECA) for the Treatment of Limbal Stem Cell Deficiency
  CHU de Quebec-Universite Laval

See all trials for Limbal stem cell deficiency →