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🏅 FDA Orphan Designation

Vonjo

PACRITINIB

Manufacturer: Sobi, Inc.

Indicated for:
Acquired secondary polycythemiaAccel.Primary myelofibrosisAccel.OBSOLETE: Inherited predisposition to essential thrombocythemiaAccel.

FDA-Approved Indications (3)

indicated for the treatment of adults with intermediate or high-risk secondary (post-polycythemia vera) myelofibrosis (MF) with a platelet count below 50 × 10 9 /L

Population: adults

Primary myelofibrosisAccelerated Approval

indicated for the treatment of adults with intermediate or high-risk primary myelofibrosis (MF) with a platelet count below 50 × 10 9 /L

Population: adults

indicated for the treatment of adults with intermediate or high-risk secondary (post-essential thrombocythemia) myelofibrosis (MF) with a platelet count below 50 × 10 9 /L

Population: adults

Indications & Usage

1 INDICATIONS AND USAGE VONJO is indicated for the treatment of adults with intermediate or high-risk primary or secondary (post-polycythemia vera or post-essential thrombocythemia) myelofibrosis (MF) with a platelet count below 50 × 10 9 /L. This indication is approved under accelerated approval based on spleen volume reduction [see Clinical Studies (14.2)] . Continued approval for this indication may be contingent upon verification and description of clinical benefit in a confirmatory trial(s). VONJO is a kinase inhibitor indicated for the treatment of adults with intermediate or high-risk primary or secondary (post-polycythemia vera or post-essential thrombocythemia) myelofibrosis with a platelet count below 50 × 10 9 /L ( 1 ). This indication is approved under accelerated approval based on spleen volume reduction. Continued approval for this indication may be contingent upon verification and description of clinical benefit in a confirmatory trial(s).

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Vonjo
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Medical disclaimer: This information is for educational purposes only. Always consult a qualified healthcare provider before making treatment decisions. Data sourced from FDA and current as of our last update.