ResearchPUBMEDMar 26
The LMSz method - an automatable scalable approach to constructing gene-specific growth charts in rare disorders.
Researchers created a new method to build growth charts for children with rare genetic disorders. Instead of needing thousands of patients, this method uses a smaller group of patients and compares their growth to standard growth charts. They tested it on six rare genetic disorders and found it works well, which could help doctors track whether children with these conditions are growing normally.
WHY IT MATTERSParents and doctors caring for children with ANKRD11, ARID1B, ASXL3, DDX3X, KMT2A, or SATB2-related disorders can now use gene-specific growth charts to monitor their child's growth instead of comparing to general population standards that don't apply to their condition.