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ResearchRSSWednesday, April 22, 2026 · 2 days ago

High pulmonary resistance indicates worse outcomes in new PH study

WHY IT MATTERS

If you have pulmonary hypertension related to heart disease, knowing that high pulmonary vascular resistance predicts worse outcomes could help your doctor decide whether to start more aggressive treatment earlier or monitor you more closely.

A study from Japan found that people with pulmonary hypertension (a condition where blood vessels in the lungs become stiff and narrow) who have higher pulmonary vascular resistance—a measure of how hard the heart has to work to pump blood through the lungs—tend to have worse health outcomes. The study also looked at whether a type of diabetes medication called SGLT2 inhibitors might help these patients.

Elevated pulmonary vascular resistance (PVR), a measure of how difficult it is for blood to move from the heart to the lungs, was associated with a higher risk of poor outcomes in people with pulmonary hypertension (PH) due to left heart disease, a real-world study in Japan shows. The study also found that SGLT2 inhibitors, […] The post High pulmonary resistance indicates worse outcomes in new PH study appeared first on Pulmonary Hypertension News .

ASK YOUR DOCTOR

Ask your doctor at your next appointment whether your pulmonary vascular resistance has been measured and what your specific number means for your treatment plan.

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pulmonary hypertensionheart diseaseprognosistreatment outcomesreal-world evidence

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