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Clinical trialUNITERARESunday, April 5, 2026 · April 5, 2026

New Recruiting Trial: Autologous T Cells Transduced With Retroviral Vectors Expressing TCRs for Participant-specific Neoantigens in Patients With Hematologic Malignancies

WHY IT MATTERS

This trial offers patients with hematologic malignancies access to a cutting-edge personalized immunotherapy that targets their cancer's unique mutations, potentially offering a new treatment option for those who may have limited alternatives.

Researchers are testing a new cancer treatment that takes a patient's own immune cells, modifies them in a lab to recognize and attack their specific cancer, and then puts them back into the body. This Phase 1 trial is for people with blood cancers like leukemia and lymphoma. The treatment is personalized—each patient's cells are customized based on their individual cancer's unique mutations.

NCT ID: NCT06904066 Title: Autologous T Cells Transduced With Retroviral Vectors Expressing TCRs for Participant-specific Neoantigens in Patients With Hematologic Malignancies Status: RECRUITING Phase: PHASE1 Sponsor: National Cancer Institute (NCI) Start date: 2026-04-05 URL: https://clinicaltrials.gov/study/NCT06904066 Source: UniteRare clinical trials database

YOU CAN ACT ON THIS

If you have a hematologic malignancy (blood cancer), check the trial's eligibility requirements at clinicaltrials.gov/study/NCT06904066 and contact the National Cancer Institute to ask if you qualify—enrollment is currently open.

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immunotherapyt-cell therapypersonalized medicinehematologic malignancyneoantigen

Related conditions

Acute lymphoblastic leukemiaT-cell prolymphocytic leukemiaAcute myeloid leukemiaB-cell chronic lymphocytic leukemiaChronic myeloid leukemia