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ResearchCLINICALTRIALSThursday, March 26, 2026 · March 26, 2026

Trial Completed: Effect of the MindUP Program on Depression, Anxiety, and Stress in Pakistani Orphan Adolescents (NCT07468994)

WHY IT MATTERS

This research demonstrates that mindfulness-based interventions can be effective mental health tools for vulnerable adolescent populations in resource-limited settings, potentially offering low-cost psychological support for orphaned youth.

Researchers in Pakistan completed a study testing whether a mindfulness program called MindUP could help orphan teenagers feel less depressed, anxious, and stressed. The program teaches techniques to calm the mind and manage difficult emotions. This study involved 61 teenagers living in orphan care institutions who often experience sadness and worry from losing their parents and living in institutional settings.

NCT ID: NCT07468994 Status: COMPLETED Conditions: Depression, Anxiety, Stress Phase: NA Enrollment: 61 Sponsor: Quaid-e-Azam University Summary: This study evaluates the effectiveness of the MindUP mindfulness-based program in reducing depression, anxiety, and stress among orphan adolescents in Pakistan. Adolescents living in orphan care institutions often experience significant psychological distress due to early life adversity, loss of parental support, and institutional living conditions. A school-based quasi-experimental design was used to examine whether participation in the MindUP program improves mental health outcomes among orph

Read the original at clinicaltrials
mental healthadolescent psychologymindfulness interventionorphan caredepression anxiety