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Clinical trialCLINICALTRIALSThursday, March 26, 2026 · March 26, 2026

Trial Now Recruiting: Vascular Disease Discovery Protocol (NCT03538639)

WHY IT MATTERS

This is a large-scale discovery study actively recruiting now that could help identify new genetic causes of inherited heart and vascular diseases, potentially leading to earlier diagnosis and treatment options for affected families.

Researchers at the National Heart, Lung, and Blood Institute are looking for 1,000 people to join a study about heart and blood vessel diseases that run in families. They want to collect information and blood samples from people who have these genetic diseases, their relatives, and healthy volunteers to better understand how genes affect the heart and blood vessels. This study is open to anyone age 2 and older who may have a genetic condition affecting their heart or blood vessels.

NCT ID: NCT03538639 Status: RECRUITING Conditions: Vascular Dysfunction, Genetic Mutations, Genetic Predisposition Enrollment: 1000 Sponsor: National Heart, Lung, and Blood Institute (NHLBI) Summary: Background: Some genetic diseases put increase the risk of heart and blood diseases, which are the number one cause of death and disability in the U.S. Researchers want to study diseases of the heart and/or blood vessels. They want to collect data and specimens from affected people, their family members, and healthy people. Objective: To study diseases of the heart and/or blood vessels. Eligibility: People age 2 and older who may have genetic disease affecting the heart and/or blood vessels

YOU CAN ACT ON THIS

If you or a family member has a genetic heart or blood vessel condition, check if you meet the age and eligibility requirements and contact the study team at clinicaltrials.gov using NCT03538639 to learn how to enroll.

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