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NewsNEJMSaturday, November 15, 2025 · November 15, 2025

Trikafta Five-Year Data Shows Sustained Lung Function in CF

WHY IT MATTERS

Confirms Trikafta as transformative long-term CF therapy. 90% of CF patients now have a modulator.

Long-term data shows sustained improvement in lung function over five years in cystic fibrosis patients with at least one F508del mutation.

Read the original at NEJM
ResearchDrug

Related conditions

Cystic fibrosis