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Clinical trialCLINICALTRIALSMonday, April 20, 2026 · 4 days ago

Trial Now Recruiting: Novel Genetic Disorders of the Immune System (NCT02257892)

WHY IT MATTERS

This trial is actively recruiting 500 participants with four specific genetic immune disorders (PI3KCD, CTLA4, STAT3GOF, and MAGT1 deficiency) — if you or a family member has one of these diagnoses, you may be eligible to enroll now and contribute to understanding these rare conditions.

Researchers are looking for adults and children with certain immune system disorders to join a study. The immune system normally helps your body fight infections, but in some people it doesn't work properly, causing frequent infections and other health problems. This study wants to understand why some immune systems fail and how to help people with these conditions. Relatives of affected people may also be able to join.

NCT ID: NCT02257892 Status: RECRUITING Conditions: PI3KCD, CTLA4, STAT3GOF, MAGT1 Enrollment: 500 Sponsor: National Institute of Allergy and Infectious Diseases (NIAID) Summary: Background: \- The immune system helps the body fight infection and disease. People with immune system problems can get infections, blood disorders, and other health problems. Researchers want to learn more about the immune system, like what causes it to not work properly. Objectives: \- To evaluate people with certain types of immune system disorders. Eligibility: \- Adults and children with an immune disorder or symptoms of one, and their relatives. Some disorders are not included in this

YOU CAN ACT ON THIS

If you have been diagnosed with PI3KCD, CTLA4, STAT3GOF, or MAGT1 deficiency, contact your doctor now to ask about enrollment or visit clinicaltrials.gov (NCT02257892) to find participating sites near you.

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immunodeficiencygenetic disorderclinical trial recruitingniaidprimary immunodeficiency

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