White platelet syndrome

White platelet syndrome is an extremely rare inherited bleeding disorder that affects how your blood clots. In this condition, the platelets — the tiny blood cells that help stop bleeding by forming clots — appear unusually pale or white under the microscope because they lack the normal internal granules (small storage packets) that contain important clotting chemicals. These granules normally release substances that help platelets stick together and form a proper clot when you are injured. Because the platelets in white platelet syndrome are missing or have reduced numbers of these granules, people with this condition tend to bruise easily and bleed more than expected from cuts, dental procedures, or surgeries. The condition is sometimes grouped with other platelet storage pool disorders. Symptoms can range from mild to moderate bleeding problems. There is currently no cure for white platelet syndrome. Treatment focuses on managing and preventing bleeding episodes. Platelet transfusions may be used for serious bleeding or before surgical procedures. Medications that help reduce bleeding, such as desmopressin (DDAVP) or antifibrinolytic drugs like tranexamic acid, may also be helpful in some patients.

Bring these to your next appointment

• Q1.How severe is my (or my child's) bleeding risk based on the test results?,What medications should I avoid because they could worsen bleeding?,Should I take any special precautions before dental procedures or surgeries?,Is desmopressin (DDAVP) an option for managing my bleeding episodes?,Should my family members be tested for this condition?,What should I do if I experience a bleeding episode that won't stop?,Are there any activities or sports I should avoid?

Common questions about White platelet syndrome

Related conditions

Other rare diseases commonly researched alongside White platelet syndrome.

• Bernard-Soulier syndrome→
• Glanzmann thrombasthenia→
• Gray platelet syndrome→
• Hermansky-Pudlak syndrome→