Visual snow syndrome

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2Active trials5Specialists8Treatment centers

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Overview

Visual snow syndrome (VSS) is a neurological condition where a person sees constant static or 'snow' across their entire visual field — similar to the static on an old television screen. This happens all the time, even with eyes closed, and is not caused by a problem with the eyes themselves. Instead, it is thought to be caused by the brain processing visual information in an unusual way. The condition is also sometimes called 'visual snow' or 'persistent positive visual phenomenon.' Along with the static, most people with VSS experience a range of other visual and non-visual symptoms. These can include seeing trails behind moving objects, light sensitivity, floaters, and difficulty seeing at night. Many people also experience tinnitus (ringing in the ears), headaches, and symptoms that overlap with migraine. The condition can range from mildly annoying to significantly disabling, depending on how severe the symptoms are. There is currently no cure for visual snow syndrome, and no FDA-approved medication specifically for it. Treatment focuses on managing individual symptoms and improving quality of life. Research into the condition is still growing, and awareness among doctors has increased significantly in recent years. Many people with VSS live full lives, though some find the symptoms affect their daily activities, work, and mental well-being.

Key symptoms:

Constant static or 'snow' across the entire field of visionSeeing trails or after-images behind moving objects (palinopsia)Increased floaters in visionSensitivity to light (photophobia)Difficulty seeing in low light or at nightSeeing patterns or colors when looking at plain surfaces (pattern glare)Ringing or buzzing in the ears (tinnitus)Feeling of unreality or detachment (depersonalization/derealization)Headaches or migrainesFatigue and difficulty concentratingAnxiety or depression related to symptomsSeeing flashes of lightHalos or starbursts around lights

Clinical phenotype terms (24)— hover any for plain English
Vitreous floatersHP:0100832Bipolar affective disorderHP:0007302PhotopsiaHP:0030786Diminished ability to concentrateHP:0031987DepersonalizationHP:5200217DerealizationHP:5200218Entoptic phenomenonHP:6001103
Inheritance

Multifactorial

Caused by a mix of several genes and environmental factors

Age of Onset

Variable

Can begin at different ages, from infancy through adulthood

Orphanet ↗NORD ↗

FDA & Trial Timeline

3 events
Sep 2025Study of Visual Perception Phenomena: Phosphene Mapping Induced by TMS and Its Relationship With Eye Movements

Skolkovo Institute of Science and Technology — NA

TrialRECRUITING
Apr 2025Investigating Brain Function in People With and Without Visual Snow Syndrome Using Adaptation to Visual Stimuli

University of Minnesota — NA

TrialRECRUITING
Jan 2024MBCT-vision VSS RCT

Guy's and St Thomas' NHS Foundation Trust — NA

TrialNOT YET RECRUITING

Data sourced from FDA regulatory filings and ClinicalTrials.gov. Updated periodically.

Treatments

No FDA-approved treatments are currently listed for Visual snow syndrome.

2 clinical trialsare actively recruiting — trials can provide access to cutting-edge therapies.

View clinical trials →

Clinical Trials

2 recruitingView all trials with filters →
N/A2 trials
Investigating Brain Function in People With and Without Visual Snow Syndrome Using Adaptation to Visual Stimuli
N/A
Actively Recruiting
PI: Michael-Paul Schallmo, Ph.D. (University of Minnesota, Department of Psychiatry ) · Sites: Minneapolis, Minnesota · Age: 1860 yrs
Study of Visual Perception Phenomena: Phosphene Mapping Induced by TMS and Its Relationship With Eye Movements
N/A
Actively Recruiting
· Sites: Moscow · Age: 1865 yrs

Specialists

5 foundView all specialists →
MP
Michael-Paul Schallmo, Ph.D.
Specialist
PI on 1 active trial
KP
Koen Van Laere, MD PhD
Specialist
PI on 1 active trial
SM
Sui H Wong, MD
MIAMI, FL
Specialist
PI on 1 active trial
PN
Patrick Freund, Prof. Dr. med. Dr. rer. nat.
PLANO, TX
Specialist
PI on 1 active trial
SW
Sui Wong
MIAMI, FL
Specialist
PI on 1 active trial

Treatment Centers

8 centers
🏥 NORD

Baylor College of Medicine Rare Disease Center

Baylor College of Medicine

📍 Houston, TX

🏥 NORD

Stanford Medicine Rare Disease Center

Stanford Medicine

📍 Stanford, CA

🔬 UDN

NIH Clinical Center Undiagnosed Diseases Program

National Institutes of Health

📍 Bethesda, MD

🔬 UDN

UCLA UDN Clinical Site

UCLA Health

📍 Los Angeles, CA

🔬 UDN

Baylor College of Medicine UDN Clinical Site

Baylor College of Medicine

📍 Houston, TX

🔬 UDN

Harvard/MGH UDN Clinical Site

Massachusetts General Hospital

📍 Boston, MA

🏥 NORD

Mayo Clinic Center for Individualized Medicine

Mayo Clinic

📍 Rochester, MN

👤 Mayo Clinic Center for Individualized Medicine

🏥 NORD

UCLA Rare Disease Day Program

UCLA Health

📍 Los Angeles, CA

Travel Grants

No travel grants are currently matched to Visual snow syndrome.

Search all travel grants →NORD Financial Assistance ↗

Community

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Latest news about Visual snow syndrome

Disease timeline:

New recruiting trial: Investigating Brain Function in People With and Without Visual Snow Syndrome Using Adaptation to Visual Stimuli

A new clinical trial is recruiting patients for Visual snow syndrome

Caregiver Resources

NORD Caregiver Resources

Support, advocacy, and financial assistance for caregivers of rare disease patients.

Mental Health Support

Rare disease caregiving can be isolating. Connect with counseling and peer support.

Family & Caregiver Grants

Financial assistance programs specifically for caregivers of rare disease patients.

Social Security Disability

Learn how rare disease patients may qualify for SSDI/SSI benefits.

Questions for your doctor

Bring these to your next appointment

  • Q1.Can you confirm that my symptoms fit the diagnosis of visual snow syndrome and that other causes have been ruled out?,Are there any treatments or medications you would recommend trying for my specific symptoms?,Should I see a neuro-ophthalmologist or migraine specialist in addition to you?,Are there lifestyle changes or triggers I should avoid to help manage my symptoms?,How will we monitor whether my condition is getting better or worse over time?,Are there any clinical trials or research studies I could participate in?,Can you refer me to a mental health professional who has experience with chronic neurological conditions?

Common questions about Visual snow syndrome

What is Visual snow syndrome?

Visual snow syndrome (VSS) is a neurological condition where a person sees constant static or 'snow' across their entire visual field — similar to the static on an old television screen. This happens all the time, even with eyes closed, and is not caused by a problem with the eyes themselves. Instead, it is thought to be caused by the brain processing visual information in an unusual way. The condition is also sometimes called 'visual snow' or 'persistent positive visual phenomenon.' Along with the static, most people with VSS experience a range of other visual and non-visual symptoms. These

How is Visual snow syndrome inherited?

Visual snow syndrome follows a multifactorial inheritance pattern. Genetic counseling can help families understand recurrence risk and testing options.

Are there clinical trials for Visual snow syndrome?

Yes — 2 recruiting clinical trials are currently listed for Visual snow syndrome on UniteRare. See the clinical trials section on this page for phase, sponsor, and site details sourced from ClinicalTrials.gov.

Which specialists treat Visual snow syndrome?

5 specialists and care centers treating Visual snow syndrome are listed on UniteRare, sourced from ClinicalTrials.gov principal investigators, published research, and the NPPES NPI registry.