T-cell prolymphocytic leukemiaNews & Research

8 curated articles for T-cell prolymphocytic leukemia — FDA updates, peer-reviewed research, clinical-trial milestones, and sponsor press releases. Sorted newest-first.

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  1. Haematologica Apr 23, 2026

    Long-term outcome of allogeneic hematopoietic cell transplantation for T-cell prolymphocytic leukemia - a study on behalf of the Chronic Malignancies Working Party of the EBMT.

    Not available.

    Why it matters: Recent peer-reviewed research on T-cell prolymphocytic leukemia that may be relevant for patients and caregivers.

  2. Annals of hematology Apr 12, 2026

    A case of T-prolymphocytic leukemia harboring RAS mutation.

    The text reports the clinical case of a 61-year-old woman with a long history of generalized pruritus who was eventually diagnosed with T-cell prolymphocytic leukemia (T-PLL), a rare and aggressive T-cell lymphoproliferative disorder. At presentation, the patient had fever, skin lesions, lymphocytos...

    Why it matters: Recent peer-reviewed research on T-cell prolymphocytic leukemia that may be relevant for patients and caregivers.

  3. Leukemia & lymphoma Apr 6, 2026

    Allogeneic transplant outcomes in T-cell prolymphocytic leukemia: a single-center retrospective study.

    T-cell prolymphocytic leukemia (T-PLL) is a rare and aggressive malignancy with a poor prognosis. Allogeneic hematopoietic stem cell transplantation (HCT) is often used for treatment, but its effectiveness remains unclear. In this study of 33 adult patients with T-PLL who underwent HCT, 5-year progr...

    Why it matters: Recent peer-reviewed research on T-cell prolymphocytic leukemia that may be relevant for patients and caregivers.

  4. Cancers Mar 28, 2026

    How We Evaluate and Treat Leukemic Presentations of Mature T-Cell Lymphomas.

    T-cell non-Hodgkin lymphomas, which arise from post-thymic mature T cells, constitute approximately 10-15% of all non-Hodgkin lymphomas. Their leukemic presentations, referred to here as mature T-cell leukemias, are relatively uncommon and present significant diagnostic and therapeutic challenges re...

    Why it matters: Recent peer-reviewed research on T-cell prolymphocytic leukemia that may be relevant for patients and caregivers.

  5. Journal of cutaneous pathology Mar 9, 2026

    Cutaneous-Only Relapse in T-Cell Prolymphocytic Leukemia With JAK2 Rearrangement.

    Cutaneous-Only Relapse in T-Cell Prolymphocytic Leukemia With JAK2 Rearrangement.

    Why it matters: Recent peer-reviewed research on T-cell prolymphocytic leukemia that may be relevant for patients and caregivers.

  6. International journal of laboratory hematology Mar 3, 2026

    Splenic B-Cell Lymphoma/Leukemia With TCL1 Gene Rearrangement.

    Splenic B-cell lymphoma/leukemia includes a group of indolent small B-cell lymphomas/leukemias that share overlapping morphological and immunophenotypic features, making accurate diagnosis challenging. Specific gene rearrangements have not been commonly associated with splenic B-cell lymphomas/leuke...

    Why it matters: Recent peer-reviewed research on T-cell prolymphocytic leukemia that may be relevant for patients and caregivers.

  7. Journal of hematology Mar 2, 2026

    A Rare Presentation of T-cell Prolymphocytic Leukemia With Abnormal Uterine Bleeding.

    T-cell prolymphocytic leukemia (T-PLL) is a rare and clinically aggressive T-cell neoplasm, which is composed of lymphoid cells that are of post-thymic T-cell origin. This is a case of a 57-year-old female with no significant medical history, who presented with a 4-month history of facial swelling, ...

    Why it matters: Recent peer-reviewed research on T-cell prolymphocytic leukemia that may be relevant for patients and caregivers.

  8. Blood neoplasia Jan 15, 2026

    Phase 1B pilot study of itacitinib with alemtuzumab in patients with T-cell prolymphocytic leukemia.

    T-cell prolymphocytic leukemia (T-PLL) is a mature T-cell neoplasm with an aggressive clinical course. Overall prognosis is poor, and treatment relies on alemtuzumab because of inadequate response to conventional chemotherapy. Three-quarters of cases harbor activating mutations in the JAK-STAT pathw...

    Why it matters: Recent peer-reviewed research on T-cell prolymphocytic leukemia that may be relevant for patients and caregivers.

More on T-cell prolymphocytic leukemia

Articles aggregated from peer-reviewed journals (PubMed), sponsor press releases, SEC 8-K filings, and FDA announcements. Original-source links are preserved on each article page. Editorial tags (Breaking / Notable / Update) reflect UniteRare's curation-time priority assessment.