Clinical trials for Sickle cell anemia
48 recruiting or active trials synced from ClinicalTrials.gov.
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Clinical trial records are synced from ClinicalTrials.gov through automated extraction.
Report missing data- RECRUITINGPhase 2NCT07369024Sub-dissociative Dose Ketamine in Treatment of Vaso-occlusive Pain Event in Children and Young AdultsMohsen Saidinejad
- RECRUITINGNCT07373639A Long-term Follow-up Study in Patients Who Received BEAM-101Beam Therapeutics Inc.
- RECRUITINGN/ANCT07402811Mindfulness-Based Intervention for Pain and Sleep in Adolescents and Young Adults With Sickle Cell DiseaseUniversity of Illinois at Chicago · PI: Dahee Wi, PhD, RN
- RECRUITINGPhase 1NCT06647979Hematopoietic Stem Cell BCL11A Enhancer Gene Editing for Severe β-HemoglobinopathiesDaniel Bauer
- RECRUITINGN/ANCT06555939Promoting Resilience Among Adolescents and Young Adults With Sickle Cell DiseaseBoston Children's Hospital
- RECRUITINGPhase 3NCT06975865The Efficacy and Safety of Rilzabrutinib in Participants Aged 10 to 65 Years With Sickle-cell DiseaseSanofi
- RECRUITINGNCT06944067Study to Understand the Genetic Risk of Developing an Immune Response After Blood Transfusions Among Individuals With Sickle Cell DiseaseNational Human Genome Research Institute (NHGRI) · PI: Neil A Hanchard, M.D.
- RECRUITINGNCT06923111PASS of Xromi Comparing Safety and Effectiveness in Children Under 2 Years With Sickle Cell Disease [PRECISE PASS]Nova Laboratories Limited · PI: Hussain Dr Mulla, PhD
- RECRUITINGPHASE1, PHASE2NCT06930703Cannabidiol in Sickle Cell DiseaseIcahn School of Medicine at Mount Sinai · PI: Susanna Curtis
- RECRUITINGN/ANCT06374238Peer Support for Adolescents and Emerging Adults With Sickle Cell PainUniversity of Pittsburgh · PI: Charles Jonassaint, PhD
- RECRUITINGNCT07001189Impact of Regional Anesthesia on Inflammatory Mechanisms During Vaso-occlusive Crisis in Sickle Cell PatientsCentre Hospitalier Universitaire de la Guadeloupe · PI: Amelie Rolle, MD
- RECRUITINGPhase 1NCT05904093Study to Evaluate the Safety and Tolerability of Escalating Doses of Fostamatinib in Subjects With Stable Sickle Cell DiseaseNational Heart, Lung, and Blood Institute (NHLBI) · PI: Swee Lay Thein, M.D.
- RECRUITINGNCT06581900Study of Vitamin B12 Metabolism in Children With Sickle Cell Disease Exposed to MEOPACHU de Reims
- ENROLLING BY INVITATIONNCT06529042SCRIPT: Sickle Cell Risk in Pregnancy ToolMount Sinai Hospital, Canada · PI: A. Kinga Malinowski, MD, MSc
- RECRUITINGPHASE1, PHASE2NCT06546670A Phase I/II Study of ITU512 in Healthy Participants and Patients With Sickle Cell DiseaseNovartis Pharmaceuticals
- RECRUITINGPhase 4NCT06526117Stroke Prevention in Nigeria 2 TrialVanderbilt University Medical Center · PI: Michael R DeBaun, MD, MPH
- RECRUITINGN/ANCT06318143mAnaging siCkle CELl disEase Through incReased AdopTion of hydroxyurEa in NigeriaNew York University
- RECRUITINGNCT06941389Comparing the Effectiveness of Matched Related Donor Hematopoietic Stem Cell Transplantation to Disease Modifying Therapy in Pediatric Patients With Sickle Cell DiseaseUniversity of Rochester
- RECRUITINGPHASE1, PHASE2NCT06417411LEARNER- Low dosE AspiRiN prEterm tRial (Angola)Instituto Nacional de Investigacao em Saude, Angola · PI: JOANA MORAIS, PhD
- RECRUITINGN/ANCT06529874Pressure Pain Tolerance in Relation to Balance and Strength in ChildrenAdly A Adam · PI: Shimaa A Ahmed, PHD
- ACTIVE NOT RECRUITINGPhase 2NCT05861453Pharmacokinetics, Pharmacodynamics and Safety of Epeleuton in Patients With Sickle Cell DiseaseAfimmune
- RECRUITINGPhase 3NCT05285917Promoting Utilization and Safety of Hydroxyurea Using Precision in AfricaBrown University · PI: Patrick T McGann, MD, MS
- RECRUITINGPhase 2NCT05583721Relationship Between Abnormal Myocardial Perfusion and Diastolic Dysfunction in Sickle Cell Disease Using PETSt. Jude Children's Research Hospital · PI: Parul Rai, MD
- ACTIVE NOT RECRUITINGN/ANCT05758766Study on Use of Omega-3 Fatty Acids to Improve Outcomes in Individuals With Sickle Cell DiseaseUniversity of Alabama at Birmingham
- RECRUITINGPHASE1, PHASE2NCT05685368Acceptance and Commitment Therapy for Adolescents and Young Adults With Sickle Cell DiseaseChildren's Hospital Los Angeles · PI: Xzania Lee, PhD
- RECRUITINGNCT07116772Serial Assessment of Fertility ExperiencesChildren's Hospital Medical Center, Cincinnati · PI: Russell E Ware, MD, PhD
- RECRUITINGPhase 3NCT05378555Oral Ketamine for Treatment of Vaso-Occlusive PainBoston Children's Hospital
- RECRUITINGN/ANCT06464458Optimizing the Management of Sickle Cell Patients on Hydroxyurea: The Value of Therapeutic Pharmacological MonitoringUniversity Hospital, Strasbourg, France · PI: Paillard
- RECRUITINGNCT06250595European Rare Blood Disorders Platform (ENROL)Hospital Universitari Vall d'Hebron Research Institute · PI: María del Mar Manú Pereira, PhD
- RECRUITINGNCT05213572Observational Study to Deeply Phenotype Major Organs in Sickle Cell Disease After Curative TherapiesNational Heart, Lung, and Blood Institute (NHLBI) · PI: Courtney F Joseph, M.D.
- RECRUITINGPhase 2NCT04201210A Trial to Assess Haploidentical T-depleted Stem Cell Transplantation in Patients With SCDUniversity of Regensburg · PI: Selim Corbacioglu, MD
- RECRUITINGN/ANCT04406818Metabolic and Hemodynamic Reserve in Pediatric SCAWashington University School of Medicine · PI: Kristin P Guilliams, MD
- ACTIVE NOT RECRUITINGNCT04808778Stroke Prevention in Young Adults With Sickle Cell AnemiaVanderbilt University Medical Center · PI: Michael R DeBaun, MD, MPH
- ENROLLING BY INVITATIONPhase 3NCT04208529A Long-term Follow-up Study in Participants Who Received CTX001Vertex Pharmaceuticals Incorporated
- RECRUITINGN/ANCT04109820Effect of MitoQ on Platelet Function and Reactive Oxygen Species Generation in Patients With Sickle Cell AnemiaUniversity of Pittsburgh · PI: Ramasubramanian Kalpatthi, MD
- RECRUITINGPHASE1, PHASE2NCT04156893RH Genotype Matched RBC TransfusionsChildren's Hospital of Philadelphia · PI: Stella Chou, MD
- RECRUITINGNCT04166526A Pilot Study on Neuroimaging in SCD: Part of The Boston Consortium to Cure Sickle Cell DiseaseBoston Children's Hospital · PI: Ellen Grant, MD
- ACTIVE NOT RECRUITINGPhase 2NCT04053803An Extension Study of IMR-687 in Adult Patients With Sickle Cell AnemiaImara, Inc. · PI: Karen Tang, MD
- ENROLLING BY INVITATIONPhase 2NCT03948867Stroke Prevention With Hydroxyurea Enabled Through Research and Education (SPHERE)Children's Hospital Medical Center, Cincinnati
- RECRUITINGN/ANCT03786549Pediatric -Adult Care Transition Program of Patients With Sickle Cell DiseaseHospices Civils de Lyon
- RECRUITINGNCT03685721Genotype -Phenotype Correlation of PKLR Variants With Pyruvate Kinase, 2,3-Diphosphglycerate and Adenosine Triphosphate Activities in Red Blood Cells of People With Sickle Cell DiseaseNational Heart, Lung, and Blood Institute (NHLBI) · PI: Swee Lay Thein, M.D.
- ACTIVE NOT RECRUITINGPhase 1NCT03664830Safety of Blood Stem Cell Mobilization With Plerixafor in Patients With Sickle Cell DiseaseCity of Hope Medical Center · PI: Leo Wang, MD
- RECRUITINGPhase 1NCT03653338T-Cell Depleted Alternative Donor Bone Marrow Transplant for Sickle Cell Disease (SCD) and Other AnemiasPaul Szabolcs · PI: Paul Szabolcs, MD
- RECRUITINGPHASE1, PHASE2NCT02447874Arginine Therapy for the Treatment of Pain in Children With Sickle Cell DiseaseEmory University · PI: Claudia Morris, MD
- RECRUITINGNCT02824471Sickle Cell Disease Biofluid Chip Technology (SCD BioChip)University Hospitals Cleveland Medical Center · PI: Amma Owusu-Ansah, MD
- ACTIVE NOT RECRUITINGPHASE1, PHASE2NCT01966731Realizing Effectiveness Across Continents With Hydroxyurea (REACH)Children's Hospital Medical Center, Cincinnati · PI: Russell Ware, MD, PhD
- RECRUITINGNCT02098863Sickle Cell Clinical Research and Intervention ProgramSt. Jude Children's Research Hospital · PI: Clifford Takemoto, MD
- ACTIVE NOT RECRUITINGPHASE1, PHASE2NCT00977691Haploidentical PBMC Transplant for Severe Congenital AnemiasNational Heart, Lung, and Blood Institute (NHLBI) · PI: Courtney D Fitzhugh, M.D.