Overview
Secondary ectropion is a condition in which the eyelid, most commonly the lower eyelid, turns outward (everts) away from the surface of the eye. Unlike primary or involutional ectropion, secondary ectropion occurs as a consequence of another identifiable cause, such as scarring from trauma, surgery, burns, or skin conditions (cicatricial ectropion), facial nerve palsy (paralytic ectropion), or mechanical forces from eyelid tumors or tissue swelling. The condition primarily affects the ocular and periorbital structures. When the eyelid turns outward, the inner conjunctival surface becomes exposed, leading to symptoms such as excessive tearing (epiphora), eye irritation, redness, dryness of the exposed conjunctiva, foreign body sensation, and increased susceptibility to conjunctivitis or keratitis. If left untreated, chronic exposure of the cornea can lead to corneal ulceration and potential vision impairment. The condition may affect one or both eyes depending on the underlying cause. Treatment of secondary ectropion is directed at both the underlying cause and the ectropion itself. Conservative measures include lubricating eye drops and ointments to protect the corneal surface. Definitive treatment is usually surgical and varies depending on the etiology. Cicatricial ectropion may require skin grafting or flap procedures to release scar tissue, while paralytic ectropion may be managed with tarsorrhaphy or eyelid tightening procedures. Mechanical causes are addressed by removing the offending lesion. Early intervention is important to prevent corneal complications and preserve vision.
Variable
Can begin at different ages, from infancy through adulthood
Treatments
No FDA-approved treatments are currently listed for Secondary ectropion.
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Specialists
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Treatment Centers
8 centersBaylor College of Medicine Rare Disease Center ↗
Baylor College of Medicine
📍 Houston, TX
🏥 NORDStanford Medicine Rare Disease Center ↗
Stanford Medicine
📍 Stanford, CA
🔬 UDNNIH Clinical Center Undiagnosed Diseases Program ↗
National Institutes of Health
📍 Bethesda, MD
🔬 UDNUCLA UDN Clinical Site ↗
UCLA Health
📍 Los Angeles, CA
🔬 UDNBaylor College of Medicine UDN Clinical Site ↗
Baylor College of Medicine
📍 Houston, TX
🔬 UDNHarvard/MGH UDN Clinical Site ↗
Massachusetts General Hospital
📍 Boston, MA
🏥 NORDMayo Clinic Center for Individualized Medicine ↗
Mayo Clinic
📍 Rochester, MN
👤 Mayo Clinic Center for Individualized Medicine
🏥 NORDUCLA Rare Disease Day Program ↗
UCLA Health
📍 Los Angeles, CA
Travel Grants
No travel grants are currently matched to Secondary ectropion.
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Common questions about Secondary ectropion
What is Secondary ectropion?
Secondary ectropion is a condition in which the eyelid, most commonly the lower eyelid, turns outward (everts) away from the surface of the eye. Unlike primary or involutional ectropion, secondary ectropion occurs as a consequence of another identifiable cause, such as scarring from trauma, surgery, burns, or skin conditions (cicatricial ectropion), facial nerve palsy (paralytic ectropion), or mechanical forces from eyelid tumors or tissue swelling. The condition primarily affects the ocular and periorbital structures. When the eyelid turns outward, the inner conjunctival surface becomes expo