Rheumatoid factor-positive polyarticular juvenile idiopathic arthritis

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2FDA treatments8Treatment centers1Financial resources

Where are you in your journey?

UniteRare data is sourced from FDA.gov, ClinicalTrials.gov, Orphanet, OMIM, and NORD.
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Overview

Also known as:

Clinical phenotype terms— hover any for plain English:

Abnormal circulating interleukin concentrationHP:0011117Rheumatoid factor positiveHP:0002923Polyarticular arthritisHP:0005764Abnormal limb bone morphologyHP:0002813Progressive joint destructionHP:0005187Interphalangeal joint erosionsHP:0006252Symmetric polyarthritisHP:0040311SynovitisHP:0100769Premature epimetaphyseal fusionHP:0010588Asymmetric growthHP:0100555
Orphanet ↗NORD ↗

FDA & Trial Timeline

3 events
Jan 2026AVTOZMA: New indication approved
FDAcompleted
Apr 2017

Xatmep: FDA approved

Management of pediatric patients with active polyarticular juvenile idiopathic arthritis (pJIA) who have had an insufficient therapeutic response to, or are intolerant of, an adequate trial of first-line therapy including full dose non-steroidal anti-inflammatory agents (NSAIDs).

FDAcompleted
Apr 2013

Actemra: FDA approved

ACTEMRA® (tocilizumab) for subcutaneous injection is indicated for the treatment of active polyarticular juvenile idiopathic arthritis in patients 2 years of age and older

FDAcompleted

Data sourced from FDA regulatory filings and ClinicalTrials.gov. Updated periodically.

Treatments

2 available

Xatmep

methotrexate oral solution· Silvergate Pharmaeuticals, Inc.■ Boxed WarningOrphan Drug
Management of pediatric patients with active polyarticular juvenile idiopathic arthritis (pJIA) who have had an insufficient therapeutic response to, or are intolerant of, an adequate trial of first-l

Management of pediatric patients with active polyarticular juvenile idiopathic arthritis (pJIA) who have had an insufficient therapeutic response to, or are intolerant of, an adequate trial of first-line therapy including full dose non-steroidal anti-inflammatory agents (NSAIDs).

Actemra

tocilizumab· Genentech, Inc.■ Boxed WarningOrphan Drug

ACTEMRA� (tocilizumab) for subcutaneous injection is indicated for the treatment of active polyarticular juvenile idiopathic arthritis in patients 2 years of age and older

No actively recruiting trials found for Rheumatoid factor-positive polyarticular juvenile idiopathic arthritis at this time.

New trials open frequently. Follow this disease to get notified.

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No specialists are currently listed for Rheumatoid factor-positive polyarticular juvenile idiopathic arthritis.

View NORD Rare Disease Centers ↗Undiagnosed Disease Network ↗

Treatment Centers

8 centers
🏥 NORD

Baylor College of Medicine Rare Disease Center

Baylor College of Medicine

📍 Houston, TX

🏥 NORD

Stanford Medicine Rare Disease Center

Stanford Medicine

📍 Stanford, CA

🔬 UDN

NIH Clinical Center Undiagnosed Diseases Program

National Institutes of Health

📍 Bethesda, MD

🔬 UDN

UCLA UDN Clinical Site

UCLA Health

📍 Los Angeles, CA

🔬 UDN

Baylor College of Medicine UDN Clinical Site

Baylor College of Medicine

📍 Houston, TX

🔬 UDN

Harvard/MGH UDN Clinical Site

Massachusetts General Hospital

📍 Boston, MA

🏥 NORD

Mayo Clinic Center for Individualized Medicine

Mayo Clinic

📍 Rochester, MN

👤 Mayo Clinic Center for Individualized Medicine

🏥 NORD

UCLA Rare Disease Day Program

UCLA Health

📍 Los Angeles, CA

Financial Resources

1 resources
Actemra(tocilizumab)Genentech, Inc.

Travel Grants

No travel grants are currently matched to Rheumatoid factor-positive polyarticular juvenile idiopathic arthritis.

Search all travel grants →NORD Financial Assistance ↗

Community

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Latest news about Rheumatoid factor-positive polyarticular juvenile idiopathic arthritis

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Caregiver Resources

NORD Caregiver Resources

Support, advocacy, and financial assistance for caregivers of rare disease patients.

Mental Health Support

Rare disease caregiving can be isolating. Connect with counseling and peer support.

Family & Caregiver Grants

Financial assistance programs specifically for caregivers of rare disease patients.

Social Security Disability

Learn how rare disease patients may qualify for SSDI/SSI benefits.

Common questions about Rheumatoid factor-positive polyarticular juvenile idiopathic arthritis

What treatment and support options exist for Rheumatoid factor-positive polyarticular juvenile idiopathic arthritis?

1 patient support program are currently tracked on UniteRare for Rheumatoid factor-positive polyarticular juvenile idiopathic arthritis. See the treatments and support programs sections for copay assistance, eligibility, and contact details.