Rare carcinoma of stomach

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9Specialists8Treatment centers

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UniteRare data is sourced from FDA.gov, ClinicalTrials.gov, Orphanet, OMIM, and NORD.
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Overview

Rare carcinoma of the stomach refers to a group of uncommon cancers that start in the lining or walls of the stomach. Unlike the more common types of stomach cancer (such as typical adenocarcinoma), these rare forms include subtypes like squamous cell carcinoma of the stomach, adenosquamous carcinoma, small cell carcinoma of the stomach, hepatoid adenocarcinoma, and other unusual tissue types. Because these cancers are so uncommon, they are often grouped together under the umbrella term 'rare gastric carcinoma' or 'rare stomach cancer.' These cancers affect the stomach, which is the organ responsible for breaking down food and passing it along to the intestines. When cancer grows in the stomach, it can interfere with digestion, cause pain, and spread to nearby organs or lymph nodes if not caught early. Symptoms often include persistent stomach pain or discomfort, unexplained weight loss, difficulty swallowing, nausea, vomiting, and feeling full very quickly after eating. Some people notice blood in their stool or vomit, which is a serious warning sign. Treatment depends on the specific subtype, how advanced the cancer is, and the patient's overall health. Options typically include surgery to remove part or all of the stomach, chemotherapy, radiation therapy, and in some cases targeted therapies or immunotherapy. Because these rare subtypes behave differently from common stomach cancers, treatment can be more challenging, and patients are often encouraged to seek care at specialized cancer centers with experience in rare gastrointestinal tumors.

Also known as:

Key symptoms:

Persistent stomach pain or discomfortUnexplained weight lossFeeling full very quickly after eating small amountsNausea and vomitingDifficulty swallowingLoss of appetiteBloating after mealsBlood in vomit or black, tarry stoolsFatigue and low energyHeartburn or indigestion that does not go awaySwelling in the abdomen

Inheritance

Multifactorial

Caused by a mix of several genes and environmental factors

Age of Onset

Adult

Begins in adulthood (age 18 or older)

Orphanet ↗NORD ↗

FDA & Trial Timeline

1 event
Mar 2014Whole Exome Sequencing in Finding Causative Variants in Germline DNA Samples From Patients With Peripheral Neuropathy Receiving Paclitaxel for Breast Cancer

National Cancer Institute (NCI) — NA

TrialRECRUITING

Data sourced from FDA regulatory filings and ClinicalTrials.gov. Updated periodically.

Treatments

No FDA-approved treatments are currently listed for Rare carcinoma of stomach.

View clinical trials →

No actively recruiting trials found for Rare carcinoma of stomach at this time.

New trials open frequently. Follow this disease to get notified.

Search ClinicalTrials.gov ↗Join the Rare carcinoma of stomach community →

Specialists

9 foundView all specialists →
BP
BioNTech Responsible Person
Specialist
PI on 18 active trials
GM
Giles W. Robinson, MD
MEMPHIS, TN
Specialist
PI on 4 active trials1 Rare carcinoma of stomach publication
SP
Sandip P Patel
Birmingham, Alabama
Specialist

Rare Disease Specialist

PI on 1 active trial
JM
Jeeyun Lee, MD,PhD
Specialist
PI on 1 active trial
BS
Bryan P Schneider
Boston, Massachusetts
Specialist

Rare Disease Specialist

24 Rare carcinoma of stomach publications

Treatment Centers

8 centers
🏥 NORD

Baylor College of Medicine Rare Disease Center

Baylor College of Medicine

📍 Houston, TX

🏥 NORD

Stanford Medicine Rare Disease Center

Stanford Medicine

📍 Stanford, CA

🔬 UDN

NIH Clinical Center Undiagnosed Diseases Program

National Institutes of Health

📍 Bethesda, MD

🔬 UDN

UCLA UDN Clinical Site

UCLA Health

📍 Los Angeles, CA

🔬 UDN

Baylor College of Medicine UDN Clinical Site

Baylor College of Medicine

📍 Houston, TX

🔬 UDN

Harvard/MGH UDN Clinical Site

Massachusetts General Hospital

📍 Boston, MA

🏥 NORD

Mayo Clinic Center for Individualized Medicine

Mayo Clinic

📍 Rochester, MN

👤 Mayo Clinic Center for Individualized Medicine

🏥 NORD

UCLA Rare Disease Day Program

UCLA Health

📍 Los Angeles, CA

Travel Grants

No travel grants are currently matched to Rare carcinoma of stomach.

Search all travel grants →NORD Financial Assistance ↗

Community

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Latest news about Rare carcinoma of stomach

Disease timeline:

New trial: Whole Exome Sequencing in Finding Causative Variants in Germline DNA Samples From Patients With Peri

Phase NA trial recruiting. Laboratory Biomarker Analysis

Caregiver Resources

NORD Caregiver Resources

Support, advocacy, and financial assistance for caregivers of rare disease patients.

Mental Health Support

Rare disease caregiving can be isolating. Connect with counseling and peer support.

Family & Caregiver Grants

Financial assistance programs specifically for caregivers of rare disease patients.

Social Security Disability

Learn how rare disease patients may qualify for SSDI/SSI benefits.

Questions for your doctor

Bring these to your next appointment

  • Q1.What specific subtype of rare stomach carcinoma do I have, and how does that affect my treatment options?,Has my tumor been tested for HER2, PD-L1, microsatellite instability, and other markers that might guide treatment?,Should I consider genetic testing to see if my cancer is linked to an inherited syndrome that could affect my family members?,Am I a candidate for surgery, and if so, what will my digestion and eating be like afterward?,Are there any clinical trials for my specific type of stomach cancer that I should consider?,What support services — such as nutrition counseling, mental health support, or palliative care — are available to me?,How will we know if the treatment is working, and what is the plan if the cancer comes back or spreads?

Common questions about Rare carcinoma of stomach

What is Rare carcinoma of stomach?

Rare carcinoma of the stomach refers to a group of uncommon cancers that start in the lining or walls of the stomach. Unlike the more common types of stomach cancer (such as typical adenocarcinoma), these rare forms include subtypes like squamous cell carcinoma of the stomach, adenosquamous carcinoma, small cell carcinoma of the stomach, hepatoid adenocarcinoma, and other unusual tissue types. Because these cancers are so uncommon, they are often grouped together under the umbrella term 'rare gastric carcinoma' or 'rare stomach cancer.' These cancers affect the stomach, which is the organ res

How is Rare carcinoma of stomach inherited?

Rare carcinoma of stomach follows a multifactorial inheritance pattern. Genetic counseling can help families understand recurrence risk and testing options.

At what age does Rare carcinoma of stomach typically begin?

Typical onset of Rare carcinoma of stomach is adult. Age of onset can vary across affected individuals.

Which specialists treat Rare carcinoma of stomach?

9 specialists and care centers treating Rare carcinoma of stomach are listed on UniteRare, sourced from ClinicalTrials.gov principal investigators, published research, and the NPPES NPI registry.