Overview
Radiculomegaly of canine teeth with congenital cataract is an extremely rare genetic condition that combines two main features: unusually long roots on the canine teeth (called radiculomegaly) and cataracts that are present at birth (congenital cataracts). Radiculomegaly means that the roots of certain teeth, especially the canine teeth (the pointed teeth on either side of your front teeth), grow much longer than normal. This can sometimes cause problems with dental alignment, tooth eruption, or may require special dental care. Congenital cataracts mean that the lens of the eye is cloudy from birth, which can affect vision and may need surgical treatment early in life to prevent long-term vision problems. Because this condition is so rare, very few cases have been described in the medical literature. The exact genetic cause is not fully understood, though it appears to run in families. Treatment focuses on managing each symptom individually. Eye surgery may be needed to remove cataracts and restore vision, and regular dental monitoring is important to address any complications from the abnormally long tooth roots. Patients benefit from a team approach involving eye doctors, dentists, and geneticists working together to provide the best care.
Also known as:
Key symptoms:
Unusually long roots on canine teethCloudy lenses in the eyes present from birth (congenital cataracts)Vision problems or blurred vision from birthPossible delayed eruption of teethDental crowding or misalignmentPossible difficulty with tooth extraction due to long rootsSensitivity to light due to cataracts
Autosomal dominant
Passed on from just one parent; each child has about a 50% chance of inheriting it
Neonatal
Begins at or shortly after birth (first 4 weeks)
Treatments
No FDA-approved treatments are currently listed for Radiculomegaly of canine teeth- congenital cataract.
View clinical trials →Clinical Trials
View all trials with filters →No actively recruiting trials found for Radiculomegaly of canine teeth- congenital cataract at this time.
New trials open frequently. Follow this disease to get notified.
Specialists
View all specialists →No specialists are currently listed for Radiculomegaly of canine teeth- congenital cataract.
Treatment Centers
8 centersBaylor College of Medicine Rare Disease Center ↗
Baylor College of Medicine
📍 Houston, TX
🏥 NORDStanford Medicine Rare Disease Center ↗
Stanford Medicine
📍 Stanford, CA
🔬 UDNNIH Clinical Center Undiagnosed Diseases Program ↗
National Institutes of Health
📍 Bethesda, MD
🔬 UDNUCLA UDN Clinical Site ↗
UCLA Health
📍 Los Angeles, CA
🔬 UDNBaylor College of Medicine UDN Clinical Site ↗
Baylor College of Medicine
📍 Houston, TX
🔬 UDNHarvard/MGH UDN Clinical Site ↗
Massachusetts General Hospital
📍 Boston, MA
🏥 NORDMayo Clinic Center for Individualized Medicine ↗
Mayo Clinic
📍 Rochester, MN
👤 Mayo Clinic Center for Individualized Medicine
🏥 NORDUCLA Rare Disease Day Program ↗
UCLA Health
📍 Los Angeles, CA
Travel Grants
No travel grants are currently matched to Radiculomegaly of canine teeth- congenital cataract.
Community
No community posts yet. Be the first to share your experience with Radiculomegaly of canine teeth- congenital cataract.
Start the conversation →Latest news about Radiculomegaly of canine teeth- congenital cataract
No recent news articles for Radiculomegaly of canine teeth- congenital cataract.
Follow this condition to be notified when news becomes available.
Caregiver Resources
NORD Caregiver Resources
Support, advocacy, and financial assistance for caregivers of rare disease patients.
Mental Health Support
Rare disease caregiving can be isolating. Connect with counseling and peer support.
Family & Caregiver Grants
Financial assistance programs specifically for caregivers of rare disease patients.
Social Security Disability
Learn how rare disease patients may qualify for SSDI/SSI benefits.
Questions for your doctor
Bring these to your next appointment
- Q1.How soon should my child have cataract surgery, and what are the risks?,What kind of vision correction will my child need after surgery?,How often should we get dental X-rays to monitor the tooth roots?,Will my child need orthodontic treatment, and does the long root issue affect that?,Is genetic testing available to confirm the diagnosis or help with family planning?,Are there other health problems we should watch for with this condition?,Should other family members be screened for this condition?
Common questions about Radiculomegaly of canine teeth- congenital cataract
What is Radiculomegaly of canine teeth- congenital cataract?
Radiculomegaly of canine teeth with congenital cataract is an extremely rare genetic condition that combines two main features: unusually long roots on the canine teeth (called radiculomegaly) and cataracts that are present at birth (congenital cataracts). Radiculomegaly means that the roots of certain teeth, especially the canine teeth (the pointed teeth on either side of your front teeth), grow much longer than normal. This can sometimes cause problems with dental alignment, tooth eruption, or may require special dental care. Congenital cataracts mean that the lens of the eye is cloudy from
How is Radiculomegaly of canine teeth- congenital cataract inherited?
Radiculomegaly of canine teeth- congenital cataract follows a autosomal dominant inheritance pattern. Genetic counseling can help families understand recurrence risk and testing options.
At what age does Radiculomegaly of canine teeth- congenital cataract typically begin?
Typical onset of Radiculomegaly of canine teeth- congenital cataract is neonatal. Age of onset can vary across affected individuals.