Psychogenic movement disorders

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3Active trials6Specialists8Treatment centers

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UniteRare data is sourced from FDA.gov, ClinicalTrials.gov, Orphanet, OMIM, and NORD.
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Overview

Psychogenic movement disorders (PMDs), also called functional movement disorders (FMDs), are conditions where a person experiences involuntary movements — such as tremors, jerks, or abnormal postures — that are not caused by a structural brain disease or a known neurological condition. Instead, these movements arise from how the brain is processing and generating movement signals, often linked to psychological stress, trauma, or emotional distress. The condition is also sometimes called conversion disorder with motor symptoms, or functional neurological symptom disorder (FND). Despite the name 'psychogenic,' the symptoms are very real and not made up or faked. The brain is genuinely producing these movements, just not in the usual way. People with PMDs may experience shaking, sudden jerking movements, difficulty walking, muscle spasms, or weakness that can come and go or be constant. Symptoms can be disabling and significantly affect daily life. The condition is more common than many people realize and is one of the more frequent reasons people visit neurology clinics. Treatment focuses on a combination of physical therapy, psychological therapy (especially cognitive behavioral therapy), and education about the condition. With the right support, many people see meaningful improvement. Early diagnosis and a compassionate, team-based approach are key to better outcomes.

Also known as:

Key symptoms:

Tremors or shaking that may come and goSudden jerking movements of the limbs or body (myoclonus-like jerks)Abnormal postures or muscle spasms (dystonia-like movements)Difficulty walking or an unusual walking patternWeakness or paralysis in one or more limbsSlurred or difficult speechInvoluntary facial movements or grimacingSymptoms that change or shift over timeSymptoms that improve when distractedFatigue and low energyAnxiety or depression alongside movement symptomsSensitivity to stress — symptoms often worsen during stressful periodsEpisodes that look like seizures but without typical brain wave changes

Clinical phenotype terms (3)— hover any for plain English
Inheritance

Sporadic

Usually appears on its own, not inherited from a parent

Age of Onset

Variable

Can begin at different ages, from infancy through adulthood

Orphanet ↗NORD ↗

FDA & Trial Timeline

3 events
Sep 2024Pilot Neurobehavioral Therapy for Functional Neurological Disorder

Rhode Island Hospital — NA

TrialRECRUITING
Apr 2021Heart Rate Variability Biofeedback Training in Psychogenic Disorders

University Hospital, Montpellier — NA

TrialRECRUITING
Jul 2017Modulating Movement Intention Via Cortical Stimulation

NYU Langone Health — NA

TrialRECRUITING

Data sourced from FDA regulatory filings and ClinicalTrials.gov. Updated periodically.

Treatments

No FDA-approved treatments are currently listed for Psychogenic movement disorders.

3 clinical trialsare actively recruiting — trials can provide access to cutting-edge therapies.

View clinical trials →

Clinical Trials

3 recruitingView all trials with filters →
N/A3 trials
Heart Rate Variability Biofeedback Training in Psychogenic Disorders
N/A
Actively Recruiting
PI: Philippe COUBES, MD, PhD (Montpellier University Hospital) · Sites: Montpellier · Age: 1875 yrs
Modulating Movement Intention Via Cortical Stimulation
N/A
Actively Recruiting
PI: Biyu He, MD (NYU Langone Health) · Sites: New York, New York · Age: 1865 yrs
Pilot Neurobehavioral Therapy for Functional Neurological Disorder
N/A
Actively Recruiting
PI: W. Curt LaFrance Jr, MD, MPH (Brown University Health) · Sites: Providence, Rhode Island · Age: 1870 yrs

Specialists

6 foundView all specialists →
WM
W. Curt LaFrance Jr, MD, MPH
Specialist
PI on 1 active trial
PP
Philippe COUBES, MD, PhD
Specialist
PI on 1 active trial
BM
Biyu He, MD
Specialist
PI on 1 active trial
HM
Hyun Joo Cho, M.D.
Specialist
PI on 1 active trial
XM
Xin Xin Yu, MD
Specialist
PI on 2 active trials

Treatment Centers

8 centers
🏥 NORD

Baylor College of Medicine Rare Disease Center

Baylor College of Medicine

📍 Houston, TX

🏥 NORD

Stanford Medicine Rare Disease Center

Stanford Medicine

📍 Stanford, CA

🔬 UDN

NIH Clinical Center Undiagnosed Diseases Program

National Institutes of Health

📍 Bethesda, MD

🔬 UDN

UCLA UDN Clinical Site

UCLA Health

📍 Los Angeles, CA

🔬 UDN

Baylor College of Medicine UDN Clinical Site

Baylor College of Medicine

📍 Houston, TX

🔬 UDN

Harvard/MGH UDN Clinical Site

Massachusetts General Hospital

📍 Boston, MA

🏥 NORD

Mayo Clinic Center for Individualized Medicine

Mayo Clinic

📍 Rochester, MN

👤 Mayo Clinic Center for Individualized Medicine

🏥 NORD

UCLA Rare Disease Day Program

UCLA Health

📍 Los Angeles, CA

Travel Grants

No travel grants are currently matched to Psychogenic movement disorders.

Search all travel grants →NORD Financial Assistance ↗

Community

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Latest news about Psychogenic movement disorders

Disease timeline:

New recruiting trial: Pilot Neurobehavioral Therapy for Functional Neurological Disorder

A new clinical trial is recruiting patients for Psychogenic movement disorders

New recruiting trial: Modulating Movement Intention Via Cortical Stimulation

A new clinical trial is recruiting patients for Psychogenic movement disorders

New recruiting trial: Heart Rate Variability Biofeedback Training in Psychogenic Disorders

A new clinical trial is recruiting patients for Psychogenic movement disorders

Caregiver Resources

NORD Caregiver Resources

Support, advocacy, and financial assistance for caregivers of rare disease patients.

Mental Health Support

Rare disease caregiving can be isolating. Connect with counseling and peer support.

Family & Caregiver Grants

Financial assistance programs specifically for caregivers of rare disease patients.

Social Security Disability

Learn how rare disease patients may qualify for SSDI/SSI benefits.

Questions for your doctor

Bring these to your next appointment

  • Q1.How confident are you in this diagnosis, and what specific signs led you to it?,What type of therapy do you recommend, and how do I find a therapist experienced in functional movement disorders?,Are there any medications that might help my symptoms or any co-existing conditions like anxiety or depression?,What should I do if I have a severe episode at home — is there an emergency plan I should follow?,How long does treatment usually take, and what does improvement look like?,Are there any activities or situations I should avoid, or is it better to stay as active as possible?,Can you refer me to a multidisciplinary team or a specialist center that treats functional neurological disorders?

Common questions about Psychogenic movement disorders

What is Psychogenic movement disorders?

Psychogenic movement disorders (PMDs), also called functional movement disorders (FMDs), are conditions where a person experiences involuntary movements — such as tremors, jerks, or abnormal postures — that are not caused by a structural brain disease or a known neurological condition. Instead, these movements arise from how the brain is processing and generating movement signals, often linked to psychological stress, trauma, or emotional distress. The condition is also sometimes called conversion disorder with motor symptoms, or functional neurological symptom disorder (FND). Despite the name

How is Psychogenic movement disorders inherited?

Psychogenic movement disorders follows a sporadic inheritance pattern. Genetic counseling can help families understand recurrence risk and testing options.

Are there clinical trials for Psychogenic movement disorders?

Yes — 3 recruiting clinical trials are currently listed for Psychogenic movement disorders on UniteRare. See the clinical trials section on this page for phase, sponsor, and site details sourced from ClinicalTrials.gov.

Which specialists treat Psychogenic movement disorders?

6 specialists and care centers treating Psychogenic movement disorders are listed on UniteRare, sourced from ClinicalTrials.gov principal investigators, published research, and the NPPES NPI registry.